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The map label for this gene is copR [H]

Identifier: 125624522

GI number: 125624522

Start: 1709460

End: 1709915

Strand: Reverse

Name: copR [H]

Synonym: llmg_1731

Alternate gene names: 125624522

Gene position: 1709915-1709460 (Counterclockwise)

Preceding gene: 125624523

Following gene: 125624521

Centisome position: 67.6

GC content: 35.75

Gene sequence:

>456_bases
ATGAACGAAATAGAATTTAATGTTTCAAATGCCGAATTAATCGTTATGCGTGTAATTTGGTCTTTAGGAGAAGCACGAGT
TGATGAGATTTATGCCCAGATTCCTCAAGAATTAGAATGGTCTTTAGCCACGGTAAAAACCTTGCTTGGCCGTTTAGTAA
AAAAAGAAATGCTGAGTACCGAAAAAGAAGGAAGAAAATTTGTTTATCGACCTTTGATGGAAGAATGTACAGCAATTAAT
TTGATGGCAGATGGACTGATTCAAAAAGTCTGCCAAACAAAACATGTAAATGTTTTACAAGAAATGATTGAAAAATCTAC
TTTAACTGCACAAGATTTGGAGTTTTTGCAAGAATCGCTTAAAGCCAAAGAAGCGGTTGAGCAAAAGCATTGTAATTGTC
TAGAAACCAGTGGTCTTTGCGCCTGCAAACATGAACATGAGCAAATTTCTGCTTAG

Upstream 100 bases:

>100_bases
TATGAGATTCGAATCTTTATTTTTTTGAGTTGAATACTTGACTTTTAGTGTTTACACGTGTAAACTTATTTTATGAAAAC
GAATATGGAAAGGAGAAAAA

Downstream 100 bases:

>100_bases
AAAAGAGAGAATTGAAAAATGAAAGAAACTTTAAAAATTGATGGAATGACTTGTGATCACTGCGTGATGCACGTAACAAA
TGCTTTAGAATCAGTTGAAG

Product: transcriptional regulator

Products: NA

Alternate protein names: CopAB ATPases metal-fist type repressor [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNEIEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLSTEKEGRKFVYRPLMEECTAIN
LMADGLIQKVCQTKHVNVLQEMIEKSTLTAQDLEFLQESLKAKEAVEQKHCNCLETSGLCACKHEHEQISA

Sequences:

>Translated_151_residues
MNEIEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLSTEKEGRKFVYRPLMEECTAIN
LMADGLIQKVCQTKHVNVLQEMIEKSTLTAQDLEFLQESLKAKEAVEQKHCNCLETSGLCACKHEHEQISA
>Mature_151_residues
MNEIEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLSTEKEGRKFVYRPLMEECTAIN
LMADGLIQKVCQTKHVNVLQEMIEKSTLTAQDLEFLQESLKAKEAVEQKHCNCLETSGLCACKHEHEQISA

Specific function: Acts as a copper responsive repressor. Binds to DNA in complex with Zn(2+), repressing the transcription of the copYZAB operon. Exchange of the bound zinc by two copper ions delivered by CopZ Cu(1+)-bound form causes release of CopY from the promoter, lea

COG id: COG3682

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BlaI transcriptional regulatory family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014071
- InterPro:   IPR005650
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03965 Pencillinase_R [H]

EC number: NA

Molecular weight: Translated: 17239; Mature: 17239

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEIEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLST
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKEGRKFVYRPLMEECTAINLMADGLIQKVCQTKHVNVLQEMIEKSTLTAQDLEFLQESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KAKEAVEQKHCNCLETSGLCACKHEHEQISA
HHHHHHHHHHCCHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNEIEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLST
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKEGRKFVYRPLMEECTAINLMADGLIQKVCQTKHVNVLQEMIEKSTLTAQDLEFLQESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KAKEAVEQKHCNCLETSGLCACKHEHEQISA
HHHHHHHHHHCCHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7876197 [H]