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The map label for this gene is nrdF [H]

Identifier: 125624347

GI number: 125624347

Start: 1516864

End: 1517841

Strand: Direct

Name: nrdF [H]

Synonym: llmg_1544

Alternate gene names: 125624347

Gene position: 1516864-1517841 (Clockwise)

Preceding gene: 125624346

Following gene: 125624351

Centisome position: 59.97

GC content: 36.61

Gene sequence:

>978_bases
ATGTCTGAAACTGAAAATCTTACTGTCCCCACTTATTATAGTGCGATTGACTGGAATTCTATTGAAGATTCAATCGATAA
ATACACTTGGGAGAAATTAACTAGCCAATTCTGGTTGGATACACGTGTTCCTGTCTCTAATGACTTGGACGATTGGCGTA
AATTGCCACAGCTTGAGCGTGATACTTTTGCTAAAGCCTTCGCTGGATTGACTCTCCTTGATACTTTACAATCAGTAGAT
GGGGCTGAAGTCCTCAAACATGATGCGAGAACTCCTCAAGAAATTGCTTGTTTCAATAATATCCAATTTATGGAGTCAGT
CCATGCTAAATCTTATTCTACAATTTTCTCAACTTTAAATACTAAAAAGGAAATTGAAGAACTCTTTAACTGGGTGGATA
CCAATGTCTATATGCAGACAAAGGCTGAAATCATCAATAAGATTTATGAATCTGGCACCGCTCTTCAAAAGAAAGTGGCT
TCTGTATTTCTTGAAACTTGCCTCTTCTATTCAGGATTCTATACACCTTTACTTTATCTTGGAAATAATAAGATGATTAA
CTCAGCAGAAATTATCAAGTTGATTATTCGTGATGAATCTGTACACGGTACTTATATTGGTTATAAATTCCAGCTTGGTT
TTAATGAATTATCTGAAGATGAGCAAAGTGAATTCCGTGATTGGATGTATGAGCTCCTCTACAAACTCTACGAAAATGAA
GAAAACTACTCTCATTTACTTTATGATAAAGTGGGTTGGACTGATGAAGTCTTAACTTTCTTACGCTATAACGCTAATAA
GGCCTTAATGAATCTCGGACAAGACCCACTTTTCCCTGATACTGCAGCCGATGTCAATCCTGTTGTCATGAACGGAATTT
CAACTTCTTCATCAAACCATGACTTCTTCTCACAAGTTGGTAATTCTTACCTCCTTGGTGAAGTGGAAGCAATGTCTGAC
GAAGATTATGACATTTAA

Upstream 100 bases:

>100_bases
AGTTTTTGGTGTCATGAGCTAGCTATTTTTACTGACGACATTGTCAGTGATAAAAAATTTACTGACAGTAATTGTCGGTA
GCTAAAAAGAGAGAAATAAT

Downstream 100 bases:

>100_bases
TTAAATAAATTTTAAAGTCTGTCAGTAATTAAGTTATAAACTTAATTACTGACAGACTTTTTATTTGAACAAAAAAAGAG
AAGATAAATCTTCTCTTTCA

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSETENLTVPTYYSAIDWNSIEDSIDKYTWEKLTSQFWLDTRVPVSNDLDDWRKLPQLERDTFAKAFAGLTLLDTLQSVD
GAEVLKHDARTPQEIACFNNIQFMESVHAKSYSTIFSTLNTKKEIEELFNWVDTNVYMQTKAEIINKIYESGTALQKKVA
SVFLETCLFYSGFYTPLLYLGNNKMINSAEIIKLIIRDESVHGTYIGYKFQLGFNELSEDEQSEFRDWMYELLYKLYENE
ENYSHLLYDKVGWTDEVLTFLRYNANKALMNLGQDPLFPDTAADVNPVVMNGISTSSSNHDFFSQVGNSYLLGEVEAMSD
EDYDI

Sequences:

>Translated_325_residues
MSETENLTVPTYYSAIDWNSIEDSIDKYTWEKLTSQFWLDTRVPVSNDLDDWRKLPQLERDTFAKAFAGLTLLDTLQSVD
GAEVLKHDARTPQEIACFNNIQFMESVHAKSYSTIFSTLNTKKEIEELFNWVDTNVYMQTKAEIINKIYESGTALQKKVA
SVFLETCLFYSGFYTPLLYLGNNKMINSAEIIKLIIRDESVHGTYIGYKFQLGFNELSEDEQSEFRDWMYELLYKLYENE
ENYSHLLYDKVGWTDEVLTFLRYNANKALMNLGQDPLFPDTAADVNPVVMNGISTSSSNHDFFSQVGNSYLLGEVEAMSD
EDYDI
>Mature_324_residues
SETENLTVPTYYSAIDWNSIEDSIDKYTWEKLTSQFWLDTRVPVSNDLDDWRKLPQLERDTFAKAFAGLTLLDTLQSVDG
AEVLKHDARTPQEIACFNNIQFMESVHAKSYSTIFSTLNTKKEIEELFNWVDTNVYMQTKAEIINKIYESGTALQKKVAS
VFLETCLFYSGFYTPLLYLGNNKMINSAEIIKLIIRDESVHGTYIGYKFQLGFNELSEDEQSEFRDWMYELLYKLYENEE
NYSHLLYDKVGWTDEVLTFLRYNANKALMNLGQDPLFPDTAADVNPVVMNGISTSSSNHDFFSQVGNSYLLGEVEAMSDE
DYDI

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI42544136, Length=199, Percent_Identity=25.6281407035176, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789031, Length=312, Percent_Identity=48.7179487179487, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1788567, Length=333, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 37548; Mature: 37417

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETENLTVPTYYSAIDWNSIEDSIDKYTWEKLTSQFWLDTRVPVSNDLDDWRKLPQLER
CCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHH
DTFAKAFAGLTLLDTLQSVDGAEVLKHDARTPQEIACFNNIQFMESVHAKSYSTIFSTLN
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHC
TKKEIEELFNWVDTNVYMQTKAEIINKIYESGTALQKKVASVFLETCLFYSGFYTPLLYL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEE
GNNKMINSAEIIKLIIRDESVHGTYIGYKFQLGFNELSEDEQSEFRDWMYELLYKLYENE
CCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHCC
ENYSHLLYDKVGWTDEVLTFLRYNANKALMNLGQDPLFPDTAADVNPVVMNGISTSSSNH
CCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHEECCCCCCCCC
DFFSQVGNSYLLGEVEAMSDEDYDI
HHHHHCCCCEEEEEHHHCCCCCCCC
>Mature Secondary Structure 
SETENLTVPTYYSAIDWNSIEDSIDKYTWEKLTSQFWLDTRVPVSNDLDDWRKLPQLER
CCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHH
DTFAKAFAGLTLLDTLQSVDGAEVLKHDARTPQEIACFNNIQFMESVHAKSYSTIFSTLN
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHC
TKKEIEELFNWVDTNVYMQTKAEIINKIYESGTALQKKVASVFLETCLFYSGFYTPLLYL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEE
GNNKMINSAEIIKLIIRDESVHGTYIGYKFQLGFNELSEDEQSEFRDWMYELLYKLYENE
CCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHCC
ENYSHLLYDKVGWTDEVLTFLRYNANKALMNLGQDPLFPDTAADVNPVVMNGISTSSSNH
CCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHEECCCCCCCCC
DFFSQVGNSYLLGEVEAMSDEDYDI
HHHHHCCCCEEEEEHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]