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The map label for this gene is folQ

Identifier: 125624155

GI number: 125624155

Start: 1311762

End: 1312262

Strand: Reverse

Name: folQ

Synonym: llmg_1335

Alternate gene names: 125624155

Gene position: 1312262-1311762 (Counterclockwise)

Preceding gene: 125624156

Following gene: 125624154

Centisome position: 51.88

GC content: 33.53

Gene sequence:

>501_bases
ATGAATGAGGATTTGATTTCTCAAATAAAAGAAGTGGTAACTGCTGAAAATCAGGAAAAATTGATAAAAATTATTCAATT
ACTGGAAAGTTCAAATTATGAGTTACGTGGTAAAATTAACCCAGATTTGCAACTTTCAGCCAGTGCCCTAGTTTTCAAAG
AAGATAAATTGTTTTTTATTGAGCATCCTTATCAGAAGGAGCTCTTACTTCCTGCTGGGCATGTTGAATTGAAAGAAAGC
CCGTTGGACACTGCGATTCGCGAGTTTCATGAAGAGACAGGTTTTTTTGCAAAAAAAATGGGTAAGCTAGTAGATGTTAA
TTTGATTGATATTCCATTTAATGAAACAAAAAATGAAAAAAAACATCAGCACATTGATTTTCGCTATCTCTTGGAGTTGG
AAGAACAAGAAGCTGAGCTTGCTGAGCTACCTTTTTTTCTCCTTGAACTAGAAGAAGCACCAGAAGAGTTTAAAAAGTAT
TATCGTTATAAGAACATATAA

Upstream 100 bases:

>100_bases
GACAAATGGTTGCTGATGGTGGACGTATCCTTAGAGTTCATGATGTGAAAGAAACGAAACGTTTGCTTGACGCAATTGAA
ATTTATAAGGAATTTTAATC

Downstream 100 bases:

>100_bases
TAGAAAAGGTCAAAAATGTCTATTGAACAAGCATTAGAATGGATACATTCACGATTAAAATTTAATATTCGCCCAGGGCT
AAATCGAGTTTCAGCACTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Dihydroneopterin triphosphate pyrophosphohydrolase

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MNEDLISQIKEVVTAENQEKLIKIIQLLESSNYELRGKINPDLQLSASALVFKEDKLFFIEHPYQKELLLPAGHVELKES
PLDTAIREFHEETGFFAKKMGKLVDVNLIDIPFNETKNEKKHQHIDFRYLLELEEQEAELAELPFFLLELEEAPEEFKKY
YRYKNI

Sequences:

>Translated_166_residues
MNEDLISQIKEVVTAENQEKLIKIIQLLESSNYELRGKINPDLQLSASALVFKEDKLFFIEHPYQKELLLPAGHVELKES
PLDTAIREFHEETGFFAKKMGKLVDVNLIDIPFNETKNEKKHQHIDFRYLLELEEQEAELAELPFFLLELEEAPEEFKKY
YRYKNI
>Mature_166_residues
MNEDLISQIKEVVTAENQEKLIKIIQLLESSNYELRGKINPDLQLSASALVFKEDKLFFIEHPYQKELLLPAGHVELKES
PLDTAIREFHEETGFFAKKMGKLVDVNLIDIPFNETKNEKKHQHIDFRYLLELEEQEAELAELPFFLLELEEAPEEFKKY
YRYKNI

Specific function: Probably mediates the removal of pyrophosphate from dihydroneopterin triphosphate (DHNTP), a possible step in the pterin branch of the folate synthesis pathway

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FOLQ_LACLM (P0CI35)

Other databases:

- EMBL:   AY156932
- EMBL:   AM406671
- RefSeq:   YP_001032638.1
- GeneID:   4797940
- KEGG:   llm:llmg_1335
- eggNOG:   COG0494
- HOGENOM:   HBG516999
- OMA:   INCAVRE
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: NA

Molecular weight: Translated: 19613; Mature: 19613

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEDLISQIKEVVTAENQEKLIKIIQLLESSNYELRGKINPDLQLSASALVFKEDKLFFI
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEECCEEEEEECCCEEEE
EHPYQKELLLPAGHVELKESPLDTAIREFHEETGFFAKKMGKLVDVNLIDIPFNETKNEK
ECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCEEEECCCCCCCCCH
KHQHIDFRYLLELEEQEAELAELPFFLLELEEAPEEFKKYYRYKNI
HHHCCCHHHEEEEHHHHHHHHHCCHHHHHHHHCHHHHHHHHHCCCC
>Mature Secondary Structure
MNEDLISQIKEVVTAENQEKLIKIIQLLESSNYELRGKINPDLQLSASALVFKEDKLFFI
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEECCEEEEEECCCEEEE
EHPYQKELLLPAGHVELKESPLDTAIREFHEETGFFAKKMGKLVDVNLIDIPFNETKNEK
ECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCEEEECCCCCCCCCH
KHQHIDFRYLLELEEQEAELAELPFFLLELEEAPEEFKKYYRYKNI
HHHCCCHHHEEEEHHHHHHHHHCCHHHHHHHHCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788700