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The map label for this gene is glcK [H]

Identifier: 125624066

GI number: 125624066

Start: 1212077

End: 1212787

Strand: Direct

Name: glcK [H]

Synonym: llmg_1241

Alternate gene names: 125624066

Gene position: 1212077-1212787 (Clockwise)

Preceding gene: 125624065

Following gene: 125624067

Centisome position: 47.92

GC content: 36.85

Gene sequence:

>711_bases
ATGAAAAAAGAAACGGTCTTAGGGGTAGACCTTGGTGGGACTAAGATTCTCATTGGAGAACTTGACCAAGCTGGAAATAT
TTTGGAAAGTAAATCTTTTCGTTCAAAGGTAACTTCTCAAGTTGAAGCAGTCGAGCAAATAAAAGAAGTGATTGCTTCGT
ATTTAGAAAATGAAAAGCTCCAAGGTCAATTAGTAGCTATCAGTATTGATTTAGTAGGGAGAGTTGACTCTGAAAAAGGA
ATTTGGCATGAAATTCACCCTGAGAATGCTAAAGAGATTCCATTAGCCCAAGAAATTAGTCAAAGATTCAATTTACCAGT
TGTTATTAATAATGATGTTTCTAGTGCTAGTCTTGCAGAAATGGAGTTAGGCATCGGCAAAAAAACCAAGGATTTTATTT
ATTTGAATATCGGAACAGGAATTGCCGGCCGAATAATTGCTGAGGGTCAATTGCTAAAAGGCGGTCATTCTAATGCTGGA
GAAATCGGTCATAGTCTTGTTGGAATAAATAATCATGTAAGATGTGTCTGCGGCCGAATCGCATGTGTAGAAACTTTTGC
CTCTGGTTTAGGAATGAGTAATGAGGTTCATCGTTTAAAAAATAAATATCCAACTCAATTAGAAATTACTGACAAACATC
GTGTCAGCGGGGAGGAGATAATCAAAGCTTTTCAAAAAAATGACCCACTTGCTAAAGAAGTCGTTGAGTAA

Upstream 100 bases:

>100_bases
AGAGGGAATCATTTAAGTCAGAGGATTTATACAGATTTTGGTCTTGCAATGAAGAGTAAAACTAAGCCTGGCGATTACGC
TTAGTTAAAAAGGGGAAATC

Downstream 100 bases:

>100_bases
GCTACTAAGGGAATTGCTGAACTTATCATGAACTTAGTCAGGACGTCAGACCCAGAAGCGGTAATTTTGGGTGGAGGATT
AGCAAATAATGATATCTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKKETVLGVDLGGTKILIGELDQAGNILESKSFRSKVTSQVEAVEQIKEVIASYLENEKLQGQLVAISIDLVGRVDSEKG
IWHEIHPENAKEIPLAQEISQRFNLPVVINNDVSSASLAEMELGIGKKTKDFIYLNIGTGIAGRIIAEGQLLKGGHSNAG
EIGHSLVGINNHVRCVCGRIACVETFASGLGMSNEVHRLKNKYPTQLEITDKHRVSGEEIIKAFQKNDPLAKEVVE

Sequences:

>Translated_236_residues
MKKETVLGVDLGGTKILIGELDQAGNILESKSFRSKVTSQVEAVEQIKEVIASYLENEKLQGQLVAISIDLVGRVDSEKG
IWHEIHPENAKEIPLAQEISQRFNLPVVINNDVSSASLAEMELGIGKKTKDFIYLNIGTGIAGRIIAEGQLLKGGHSNAG
EIGHSLVGINNHVRCVCGRIACVETFASGLGMSNEVHRLKNKYPTQLEITDKHRVSGEEIIKAFQKNDPLAKEVVE
>Mature_236_residues
MKKETVLGVDLGGTKILIGELDQAGNILESKSFRSKVTSQVEAVEQIKEVIASYLENEKLQGQLVAISIDLVGRVDSEKG
IWHEIHPENAKEIPLAQEISQRFNLPVVINNDVSSASLAEMELGIGKKTKDFIYLNIGTGIAGRIIAEGQLLKGGHSNAG
EIGHSLVGINNHVRCVCGRIACVETFASGLGMSNEVHRLKNKYPTQLEITDKHRVSGEEIIKAFQKNDPLAKEVVE

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=202, Percent_Identity=29.7029702970297, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI298566315, Length=202, Percent_Identity=29.7029702970297, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4885285, Length=202, Percent_Identity=29.7029702970297, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI298566325, Length=202, Percent_Identity=29.7029702970297, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1786891, Length=235, Percent_Identity=30.2127659574468, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87081733, Length=235, Percent_Identity=26.3829787234043, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1787878, Length=136, Percent_Identity=35.2941176470588, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787363, Length=238, Percent_Identity=25.6302521008403, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082230, Length=192, Percent_Identity=29.6875, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87082127, Length=174, Percent_Identity=23.5632183908046, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 25703; Mature: 25703

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKETVLGVDLGGTKILIGELDQAGNILESKSFRSKVTSQVEAVEQIKEVIASYLENEKL
CCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QGQLVAISIDLVGRVDSEKGIWHEIHPENAKEIPLAQEISQRFNLPVVINNDVSSASLAE
CCEEEEEEEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHHHCCCCEEECCCCCCHHHHH
MELGIGKKTKDFIYLNIGTGIAGRIIAEGQLLKGGHSNAGEIGHSLVGINNHVRCVCGRI
HHHCCCCCCCCEEEEEECCCCCCEEEECCEEECCCCCCHHHHHHEEECCCCCHHHHHHHH
ACVETFASGLGMSNEVHRLKNKYPTQLEITDKHRVSGEEIIKAFQKNDPLAKEVVE
HHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MKKETVLGVDLGGTKILIGELDQAGNILESKSFRSKVTSQVEAVEQIKEVIASYLENEKL
CCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QGQLVAISIDLVGRVDSEKGIWHEIHPENAKEIPLAQEISQRFNLPVVINNDVSSASLAE
CCEEEEEEEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHHHCCCCEEECCCCCCHHHHH
MELGIGKKTKDFIYLNIGTGIAGRIIAEGQLLKGGHSNAGEIGHSLVGINNHVRCVCGRI
HHHCCCCCCCCEEEEEECCCCCCEEEECCEEECCCCCCHHHHHHEEECCCCCHHHHHHHH
ACVETFASGLGMSNEVHRLKNKYPTQLEITDKHRVSGEEIIKAFQKNDPLAKEVVE
HHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]