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The map label for this gene is glmS [H]

Identifier: 125624065

GI number: 125624065

Start: 1210978

End: 1212060

Strand: Direct

Name: glmS [H]

Synonym: llmg_1240

Alternate gene names: 125624065

Gene position: 1210978-1212060 (Clockwise)

Preceding gene: 125624064

Following gene: 125624066

Centisome position: 47.87

GC content: 33.33

Gene sequence:

>1083_bases
ATGGTTGAAGAGAATAAACCAACAATGATGACCTATATCAAGGAGGAGCAAGAAGTATTATCCAATATTTTAAAAAACTA
TCCTGATAATTGTCCAGTTATCAAAGGTAATAACTGGTTGATTCTGGCGACTGGATCAAGTATTAATGCAGCTTATAGTG
CGAAATATTATATTGAGAAAATCCTTGATGTATATTTAACGATAGAAGAACCTTTTAAATTTCATTATTATGAAAAATTA
AAAGAAGAAACCGATAACGTTATCGGTATTTCTCAAAGTGGAGAAAGTACTTCAACCATTGACGCTCTTAAAGCCATTAA
AAAATTGAAACTAGAACTTACCATGTACGGATTGACAAGTAAAAGGGAAAGTGAGCTTGCCCAAGTAGTCAATGAAGTGA
TCGAAATTGAAAATGGGATTGAACGTGTTGGTTATGTCACAAAAGGATTCACAGCAACTATTTTTAAATTAATGTTAAGT
GGATTAAAAACGGCCAAAAATAAAGGTTTAATTAGTGAACAGGAAGAAGCAAAAGAACTGAGCAGTTTTGAAAAAGCTAT
CAATAAAATTTCAGATATTATTGAAAAAACGGAAAACTTTTATGAAAAATGGTCAGAGAAATTAGGCCAAGCAGAGCGTT
TTACTTCGTTATGCACTGGTGCCTTGATTGGAACAGCAATGGAAATGCAAACAAAATTTTCAGAAACGATTCGGATTCCA
AGTCAAGGAATGGATATAGAGGTTTTCATGCACGGTCCTTATTTTGAAGTCAATTCAAAGCACCAACACTTCTATATTGA
TAGTAATTCGCCAATGAATCAACGACTCTTTAACTTACGAGATTATGAAAAACGATATGTTGGTCAAGTATACACGATAA
GTTTAAATAAAAGTCAGAATGATTCTGAACTTGGATTGGACCTGGAGATTGATGAATACAAAGCAGGACTTTTTATAATT
ATTCCTTTTCAAATTTTGGCACACCATATTGCGGAAGCAAGAGGGAATCATTTAAGTCAGAGGATTTATACAGATTTTGG
TCTTGCAATGAAGAGTAAAACTAAGCCTGGCGATTACGCTTAG

Upstream 100 bases:

>100_bases
TAAAAACGTTTGCAAAAAATCCTTGACATCTTCTTTAGGATAATTTATAATAAATTTATGGAAACGTTACCGAAAACATA
AAATTTTAAAAAGGAGAGCG

Downstream 100 bases:

>100_bases
TTAAAAAGGGGAAATCATGAAAAAAGAAACGGTCTTAGGGGTAGACCTTGGTGGGACTAAGATTCTCATTGGAGAACTTG
ACCAAGCTGGAAATATTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MVEENKPTMMTYIKEEQEVLSNILKNYPDNCPVIKGNNWLILATGSSINAAYSAKYYIEKILDVYLTIEEPFKFHYYEKL
KEETDNVIGISQSGESTSTIDALKAIKKLKLELTMYGLTSKRESELAQVVNEVIEIENGIERVGYVTKGFTATIFKLMLS
GLKTAKNKGLISEQEEAKELSSFEKAINKISDIIEKTENFYEKWSEKLGQAERFTSLCTGALIGTAMEMQTKFSETIRIP
SQGMDIEVFMHGPYFEVNSKHQHFYIDSNSPMNQRLFNLRDYEKRYVGQVYTISLNKSQNDSELGLDLEIDEYKAGLFII
IPFQILAHHIAEARGNHLSQRIYTDFGLAMKSKTKPGDYA

Sequences:

>Translated_360_residues
MVEENKPTMMTYIKEEQEVLSNILKNYPDNCPVIKGNNWLILATGSSINAAYSAKYYIEKILDVYLTIEEPFKFHYYEKL
KEETDNVIGISQSGESTSTIDALKAIKKLKLELTMYGLTSKRESELAQVVNEVIEIENGIERVGYVTKGFTATIFKLMLS
GLKTAKNKGLISEQEEAKELSSFEKAINKISDIIEKTENFYEKWSEKLGQAERFTSLCTGALIGTAMEMQTKFSETIRIP
SQGMDIEVFMHGPYFEVNSKHQHFYIDSNSPMNQRLFNLRDYEKRYVGQVYTISLNKSQNDSELGLDLEIDEYKAGLFII
IPFQILAHHIAEARGNHLSQRIYTDFGLAMKSKTKPGDYA
>Mature_360_residues
MVEENKPTMMTYIKEEQEVLSNILKNYPDNCPVIKGNNWLILATGSSINAAYSAKYYIEKILDVYLTIEEPFKFHYYEKL
KEETDNVIGISQSGESTSTIDALKAIKKLKLELTMYGLTSKRESELAQVVNEVIEIENGIERVGYVTKGFTATIFKLMLS
GLKTAKNKGLISEQEEAKELSSFEKAINKISDIIEKTENFYEKWSEKLGQAERFTSLCTGALIGTAMEMQTKFSETIRIP
SQGMDIEVFMHGPYFEVNSKHQHFYIDSNSPMNQRLFNLRDYEKRYVGQVYTISLNKSQNDSELGLDLEIDEYKAGLFII
IPFQILAHHIAEARGNHLSQRIYTDFGLAMKSKTKPGDYA

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Escherichia coli, GI1790167, Length=317, Percent_Identity=24.6056782334385, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 41106; Mature: 41106

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEENKPTMMTYIKEEQEVLSNILKNYPDNCPVIKGNNWLILATGSSINAAYSAKYYIEK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHH
ILDVYLTIEEPFKFHYYEKLKEETDNVIGISQSGESTSTIDALKAIKKLKLELTMYGLTS
HHHHHEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCC
KRESELAQVVNEVIEIENGIERVGYVTKGFTATIFKLMLSGLKTAKNKGLISEQEEAKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SSFEKAINKISDIIEKTENFYEKWSEKLGQAERFTSLCTGALIGTAMEMQTKFSETIRIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
SQGMDIEVFMHGPYFEVNSKHQHFYIDSNSPMNQRLFNLRDYEKRYVGQVYTISLNKSQN
CCCCEEEEEEECCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCC
DSELGLDLEIDEYKAGLFIIIPFQILAHHIAEARGNHLSQRIYTDFGLAMKSKTKPGDYA
CCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVEENKPTMMTYIKEEQEVLSNILKNYPDNCPVIKGNNWLILATGSSINAAYSAKYYIEK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHH
ILDVYLTIEEPFKFHYYEKLKEETDNVIGISQSGESTSTIDALKAIKKLKLELTMYGLTS
HHHHHEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCC
KRESELAQVVNEVIEIENGIERVGYVTKGFTATIFKLMLSGLKTAKNKGLISEQEEAKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SSFEKAINKISDIIEKTENFYEKWSEKLGQAERFTSLCTGALIGTAMEMQTKFSETIRIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
SQGMDIEVFMHGPYFEVNSKHQHFYIDSNSPMNQRLFNLRDYEKRYVGQVYTISLNKSQN
CCCCEEEEEEECCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCC
DSELGLDLEIDEYKAGLFIIIPFQILAHHIAEARGNHLSQRIYTDFGLAMKSKTKPGDYA
CCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]