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The map label for this gene is nsr [H]

Identifier: 125624061

GI number: 125624061

Start: 1205420

End: 1206076

Strand: Reverse

Name: nsr [H]

Synonym: llmg_1235

Alternate gene names: 125624061

Gene position: 1206076-1205420 (Counterclockwise)

Preceding gene: 125624077

Following gene: 125624060

Centisome position: 47.68

GC content: 27.55

Gene sequence:

>657_bases
ATGGAAAAAATATCTTTTCAAGATTTCTGTAAAAATGAAACTTTGCACTACTTGCCAAAACTTCCCAAAAATGTTTTTGA
TGCTTCTTTTATTGTTAATTTTAAACACAACGAAACCATTATTCATGAGAATGAACCACTTAAAAATATTTACTATATTA
TTGATGGTAAGGCTAAAATAACAGATATCCAATATAATGGGAAATCTATTTTGCTTCAATTCTTAAAGAATAAGGATTGG
ATAGGCGAATTAACAATTTTAGGAGTTGAAGAGGAAACTAAAAATGTAACTGCAATTGGAAATCTCACTTGCCTTATGAT
TCCCTTGAACATAGTAGAACGATATTTACTAATTGATATAAATTTTTTTAAAGAGCTAAGTGTCTTTCTTTCGAAAAAGT
TATTGGACAGAACTAATCACTTTTCAAAAAATCAAAGTTACGAATTAAAACATCGATTGGCCACTTTTTTATTAGAATCT
TCAAACAATGATATCTATCAAGAATCACATATTGTTGTTGCTGAGTACCTTGGTGTTTCCTACCGTCACCTCCTGCAAAT
ATTTAGTGATTTTAAATCTTTAGGATACATAGAAAAAATCGGGAAAAATAATTATAAAATTAATCATCAGAAATTAATGG
AAATTTCGATTAAATAA

Upstream 100 bases:

>100_bases
ATATTTTTTACTCTTCAAAATAAATTCTCCTTTTTTTCTAATTAACAGTTTAGGTTATTTTTGGTAGAATATATATGAGA
TATCTCATATAGGAGTAAAA

Downstream 100 bases:

>100_bases
TACGATATACTATGTTCGGAATCATGATAATATTTTTTATAATAAGGAGTCCAATTACAAGAAAATCCTGTCATTACTGA
CAGGATTCTTTATTTTTTAT

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MEKISFQDFCKNETLHYLPKLPKNVFDASFIVNFKHNETIIHENEPLKNIYYIIDGKAKITDIQYNGKSILLQFLKNKDW
IGELTILGVEEETKNVTAIGNLTCLMIPLNIVERYLLIDINFFKELSVFLSKKLLDRTNHFSKNQSYELKHRLATFLLES
SNNDIYQESHIVVAEYLGVSYRHLLQIFSDFKSLGYIEKIGKNNYKINHQKLMEISIK

Sequences:

>Translated_218_residues
MEKISFQDFCKNETLHYLPKLPKNVFDASFIVNFKHNETIIHENEPLKNIYYIIDGKAKITDIQYNGKSILLQFLKNKDW
IGELTILGVEEETKNVTAIGNLTCLMIPLNIVERYLLIDINFFKELSVFLSKKLLDRTNHFSKNQSYELKHRLATFLLES
SNNDIYQESHIVVAEYLGVSYRHLLQIFSDFKSLGYIEKIGKNNYKINHQKLMEISIK
>Mature_218_residues
MEKISFQDFCKNETLHYLPKLPKNVFDASFIVNFKHNETIIHENEPLKNIYYIIDGKAKITDIQYNGKSILLQFLKNKDW
IGELTILGVEEETKNVTAIGNLTCLMIPLNIVERYLLIDINFFKELSVFLSKKLLDRTNHFSKNQSYELKHRLATFLLES
SNNDIYQESHIVVAEYLGVSYRHLLQIFSDFKSLGYIEKIGKNNYKINHQKLMEISIK

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=181, Percent_Identity=34.2541436464088, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 25584; Mature: 25584

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKISFQDFCKNETLHYLPKLPKNVFDASFIVNFKHNETIIHENEPLKNIYYIIDGKAKI
CCCCCHHHHHCCCHHHHHHCCCHHHCCCEEEEEECCCCEEEECCCCCCEEEEEEECCEEE
TDIQYNGKSILLQFLKNKDWIGELTILGVEEETKNVTAIGNLTCLMIPLNIVERYLLIDI
EEEEECCHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCEEEEEEEHHHHHHHHEEEH
NFFKELSVFLSKKLLDRTNHFSKNQSYELKHRLATFLLESSNNDIYQESHIVVAEYLGVS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHCCC
YRHLLQIFSDFKSLGYIEKIGKNNYKINHQKLMEISIK
HHHHHHHHHHHHHCCHHHHHCCCCEEECCEEEEEEECC
>Mature Secondary Structure
MEKISFQDFCKNETLHYLPKLPKNVFDASFIVNFKHNETIIHENEPLKNIYYIIDGKAKI
CCCCCHHHHHCCCHHHHHHCCCHHHCCCEEEEEECCCCEEEECCCCCCEEEEEEECCEEE
TDIQYNGKSILLQFLKNKDWIGELTILGVEEETKNVTAIGNLTCLMIPLNIVERYLLIDI
EEEEECCHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCEEEEEEEHHHHHHHHEEEH
NFFKELSVFLSKKLLDRTNHFSKNQSYELKHRLATFLLESSNNDIYQESHIVVAEYLGVS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHCCC
YRHLLQIFSDFKSLGYIEKIGKNNYKINHQKLMEISIK
HHHHHHHHHHHHHCCHHHHHCCCCEEECCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]