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The map label for this gene is adhR [H]

Identifier: 125624077

GI number: 125624077

Start: 1223857

End: 1224258

Strand: Reverse

Name: adhR [H]

Synonym: llmg_1252

Alternate gene names: 125624077

Gene position: 1224258-1223857 (Counterclockwise)

Preceding gene: 125624086

Following gene: 125624061

Centisome position: 48.4

GC content: 27.61

Gene sequence:

>402_bases
ATGTACACTATGAAAGAAGTTTGTGATTTATGTGATATGACATATGATATACTCAAATTTTATTGCAACAAAGGATTGAT
TCCTAATGTTAAAAGAGATAAAAATAATTATAGAGTTTTTAGTAAGCATGATGTAGATTGGATTAATAGTCTTTCATGTT
TAAAACAGTGCGGAATGTCAATTATAGAAATGCAACAATACTTGGAATACTGCCTTAAGGGACAAGATACAATTAATGAA
CGAAAAATTATGTTGGCTAAGAAAAAACAAGAGCTTTTGGCTAAACTTAAAACAGTTGAAAATTCAATAGAATATATTGA
TAATAAGCAAAAGTTCTATAATGATGTACTTAATGGTACTATAAGATATGAGAGCAATCTCATAGCCGAAAGTAAAGAGT
AA

Upstream 100 bases:

>100_bases
CATCTCCTTGTTTATATTATTAATTTCTGGTACTATTTAAGTATACTACTCGTGTGTAACACCCGGTCAAATAATAAATA
TTATTTTAGGAGATTTTTTT

Downstream 100 bases:

>100_bases
AAAATTATATTTAAAAAAATGACTACAATTATGTAGTCATTTTTTAGTATTTTAAATTATTTAGATTTGTTGAATTTAAT
AAAAATATAAATAGATTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MYTMKEVCDLCDMTYDILKFYCNKGLIPNVKRDKNNYRVFSKHDVDWINSLSCLKQCGMSIIEMQQYLEYCLKGQDTINE
RKIMLAKKKQELLAKLKTVENSIEYIDNKQKFYNDVLNGTIRYESNLIAESKE

Sequences:

>Translated_133_residues
MYTMKEVCDLCDMTYDILKFYCNKGLIPNVKRDKNNYRVFSKHDVDWINSLSCLKQCGMSIIEMQQYLEYCLKGQDTINE
RKIMLAKKKQELLAKLKTVENSIEYIDNKQKFYNDVLNGTIRYESNLIAESKE
>Mature_133_residues
MYTMKEVCDLCDMTYDILKFYCNKGLIPNVKRDKNNYRVFSKHDVDWINSLSCLKQCGMSIIEMQQYLEYCLKGQDTINE
RKIMLAKKKQELLAKLKTVENSIEYIDNKQKFYNDVLNGTIRYESNLIAESKE

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15777; Mature: 15777

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTMKEVCDLCDMTYDILKFYCNKGLIPNVKRDKNNYRVFSKHDVDWINSLSCLKQCGMS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCHH
IIEMQQYLEYCLKGQDTINERKIMLAKKKQELLAKLKTVENSIEYIDNKQKFYNDVLNGT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IRYESNLIAESKE
HHCCCCCCCCCCC
>Mature Secondary Structure
MYTMKEVCDLCDMTYDILKFYCNKGLIPNVKRDKNNYRVFSKHDVDWINSLSCLKQCGMS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCHH
IIEMQQYLEYCLKGQDTINERKIMLAKKKQELLAKLKTVENSIEYIDNKQKFYNDVLNGT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IRYESNLIAESKE
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]