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The map label for this gene is llrB [H]

Identifier: 125623899

GI number: 125623899

Start: 1027727

End: 1028437

Strand: Reverse

Name: llrB [H]

Synonym: llmg_1068

Alternate gene names: 125623899

Gene position: 1028437-1027727 (Counterclockwise)

Preceding gene: 125623905

Following gene: 125623898

Centisome position: 40.66

GC content: 33.61

Gene sequence:

>711_bases
ATGAAAAAAATTTTAATTGCTGATGATGATCGGGCAATTTTGACCCTATTATCTTATAATTTTCGGCAAAATGATTACGA
AGTAACCATCGTATCAGACGGAAAAAAAGCTTATGATAAAGCTCGAAAAAATCCCTTTGATTTGCTTCTTCTTGATTTAA
TGATGCCTGAATTTTCCGGAATTGAAGTCACTAAAAAGCTTCGTAAAGAAGGTAATTTTACACCAATTTTAATTTTAACT
GCTCGCGATGATGATGAAATGAAACTGACAGGTCTGTCAGCAGGTTCTGATGAGTATTTAGATAAAACGACTCCAATGAA
AGAAATCATTGTCAGAGCTGAAGGGCTCATTCGTAGAAATCAAATGTATAATCAAACAGCTTCTGATTCTGTCAGTGAAT
CTTTGGACGAAAGTCCTGCAACACTTGTTACTGACAGACTGGTCATTGATTTTACAAAAAAAGAAGTCACTTTTGATGCA
AAAGTTTTAGACTTAACCAAAAGAGAATTTGAAATTCTAGAACTCTTAGCAAAAAGACAAGGCGAAATCATCAGCCGTGA
AGAACTTCTTCAACATTTTTGGGGAATTTCGGATACAGCAGAAACACGGACAATTGATGTCCTCATCTCAAAAATCCGTA
AAAAACTAAATAATCATTATATCAAAACAAAACGAGGATTCGGTTACTATTTTGAAGAAAATGAAACTTAA

Upstream 100 bases:

>100_bases
TTTTTTAACTCGTTTCTGCTGCCATTACCCCTTCATTTTTTTATTCAAAAATAATAATTTATTCTATACAAAGCTCCCTG
TTTTCGTTATAATTAAAAGT

Downstream 100 bases:

>100_bases
ACACATCATGCTGATGACAGTGCTGTACATCATTGCAACACTAAGCTTGGTGATTCTATCGAACCAAAATATCTTAGAAA
ATGATACAAATAGGGTATTA

Product: two-component system regulator llrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEFSGIEVTKKLRKEGNFTPILILT
ARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRAEGLIRRNQMYNQTASDSVSESLDESPATLVTDRLVIDFTKKEVTFDA
KVLDLTKREFEILELLAKRQGEIISREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET

Sequences:

>Translated_236_residues
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEFSGIEVTKKLRKEGNFTPILILT
ARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRAEGLIRRNQMYNQTASDSVSESLDESPATLVTDRLVIDFTKKEVTFDA
KVLDLTKREFEILELLAKRQGEIISREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET
>Mature_236_residues
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEFSGIEVTKKLRKEGNFTPILILT
ARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRAEGLIRRNQMYNQTASDSVSESLDESPATLVTDRLVIDFTKKEVTFDA
KVLDLTKREFEILELLAKRQGEIISREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=37.1794871794872, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=31.3304721030043, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=30.4166666666667, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786784, Length=234, Percent_Identity=28.6324786324786, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786599, Length=236, Percent_Identity=30.0847457627119, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=28.6324786324786, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=27.7056277056277, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=30.0429184549356, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=26.9230769230769, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=28.0172413793103, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=31.6666666666667, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=27.7056277056277, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786911, Length=237, Percent_Identity=26.1603375527426, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790437, Length=99, Percent_Identity=34.3434343434343, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27274; Mature: 27274

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEFSG
CCEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHCCCCCC
IEVTKKLRKEGNFTPILILTARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRAEGLIRRN
HHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHH
QMYNQTASDSVSESLDESPATLVTDRLVIDFTKKEVTFDAKVLDLTKREFEILELLAKRQ
HHHCCHHHHHHHHHHCCCCHHHEECCEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHC
GEIISREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCC
>Mature Secondary Structure
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEFSG
CCEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHCCCCCC
IEVTKKLRKEGNFTPILILTARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRAEGLIRRN
HHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHH
QMYNQTASDSVSESLDESPATLVTDRLVIDFTKKEVTFDAKVLDLTKREFEILELLAKRQ
HHHCCHHHHHHHHHHCCCCHHHEECCEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHC
GEIISREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]