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The map label for this gene is kinB [H]

Identifier: 125623898

GI number: 125623898

Start: 1026184

End: 1027737

Strand: Reverse

Name: kinB [H]

Synonym: llmg_1067

Alternate gene names: 125623898

Gene position: 1027737-1026184 (Counterclockwise)

Preceding gene: 125623899

Following gene: 125623897

Centisome position: 40.63

GC content: 34.36

Gene sequence:

>1554_bases
ATGAAACTTAAACACATCATGCTGATGACAGTGCTGTACATCATTGCAACACTAAGCTTGGTGATTCTATCGAACCAAAA
TATCTTAGAAAATGATACAAATAGGGTATTAAAAACAATAGATCAAATACAGCTTTTTTTAGAAAAACATCCTGATAATC
CCTTACCCGCTAACTTTGAACATCTTTCAAAAAATACGGTAAATTCAGATACTAAAAAAATTAAAAATGGCGCTGCCTAT
GCTCGAAGTTTAGATTCTAAAGATATTACTGTTACCAGCCCTATCTTTAGTGAAGGACAAATCGATGGCTATTTGAAAGT
TACAGAAAATCGCACGTCTACTTTCTTTACCGATTTTGCAATTATCATTTTTGCTATTATATTTTACTTGGCAGTTGCCA
TACAGGTTTTGAAATCTGCTCAGAGAGCTTATGTTTTTCGCGAAAATACTGTGGCTAAGATTAAAAATATTGAGCGAAGT
CCTTTAACGCAAAGTTATCTGATGAATGAAAATGATGACAAAATTACAACTGAGCTCAATAAATTAGGCGAAAAAATCCA
AAAGCAAGCCTTATCACACACTGAAAAGAAAGAAAATCTCTACGAATTCATCGAGTTTTTCCAATTTCCCATTTTTATTT
ATAATAATAAGGGAAAAATTCGTCGAACAAATGCTTCTTTCAAAAATGAGTTTTCAGACACCGAGAATCTTGATATTTTC
AGTCCTTATGCCGATTTCTTAAATTTTCTAGTTGACAAAATTTTACATCCAGATATACAAGAAAAACTTTTCTTCTTTGA
AAAGCTTGGCGCTTATTATCAAGTCCGCATCACTCCACTGCCCGATCTTGATAGTCGCTTCATGGTAACCATGAATGATG
TAAGTTCTTATCGTCGAACAGTTGATGCTCATAATGCCTTTATTGCCAACGTTTCTCATGAATTGAAAACACCGCTCACT
TCAATAAAGGGCTTTGCCGAATTACTTGAAACAGACACTGTTTCTCCTTCTGAAACCAAAAACTTTGCTTCAATTATCCA
TAAAGAAAGTTCTCGTTTGATGAGCCTTGTTCAGGATACTCTACTACTAACTAAGCAAAATCAACGTATTGAGAAAAAGA
AACTCAGCCTTTCTGCTCTAATTCAAAATATTTTACAAAGCTCAAGTCCCCAAATTTCTGAAAAATCTCTTCGTTTAGAA
ACACAAATTGAAGAGATTACTTTCAAAACAAATGAACAAATGGTACACAGTATTTTTGAAAATCTGATTGAAAATGCCAT
CAAATATACTCCTGCTCAGGGTCAAATTTTTGTCAGCTTACACCATGAACAAGATAAAATTATCTTCAGTGTTACTGACA
ATGGTCCTGGTTTAAGTGAAATTCAAAAAGAAAGAATCTTTGATCGCTTCTATCGTGCTGATGAGAGCCGAGCAGAGGTC
AGCGGAACAGGATTAGGACTCGCCATTGTTGAAAAGAATGTCCAAGAACTTCATGGCACAATTGATGTGGTATCTATTCT
TGGAAAAGGAACCACCTTTACCGTTAATCTTTGA

Upstream 100 bases:

>100_bases
GAAACACGGACAATTGATGTCCTCATCTCAAAAATCCGTAAAAAACTAAATAATCATTATATCAAAACAAAACGAGGATT
CGGTTACTATTTTGAAGAAA

Downstream 100 bases:

>100_bases
GTGGTCATCAGTAAATTTACTTATCAAAATAAAAAAATATTAAGACCAAGTCTCTCCAATTACGATAGAATCAACTTATC
AAGATTGGAGATTTTTTATG

Product: sensor protein kinase kinB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MKLKHIMLMTVLYIIATLSLVILSNQNILENDTNRVLKTIDQIQLFLEKHPDNPLPANFEHLSKNTVNSDTKKIKNGAAY
ARSLDSKDITVTSPIFSEGQIDGYLKVTENRTSTFFTDFAIIIFAIIFYLAVAIQVLKSAQRAYVFRENTVAKIKNIERS
PLTQSYLMNENDDKITTELNKLGEKIQKQALSHTEKKENLYEFIEFFQFPIFIYNNKGKIRRTNASFKNEFSDTENLDIF
SPYADFLNFLVDKILHPDIQEKLFFFEKLGAYYQVRITPLPDLDSRFMVTMNDVSSYRRTVDAHNAFIANVSHELKTPLT
SIKGFAELLETDTVSPSETKNFASIIHKESSRLMSLVQDTLLLTKQNQRIEKKKLSLSALIQNILQSSSPQISEKSLRLE
TQIEEITFKTNEQMVHSIFENLIENAIKYTPAQGQIFVSLHHEQDKIIFSVTDNGPGLSEIQKERIFDRFYRADESRAEV
SGTGLGLAIVEKNVQELHGTIDVVSILGKGTTFTVNL

Sequences:

>Translated_517_residues
MKLKHIMLMTVLYIIATLSLVILSNQNILENDTNRVLKTIDQIQLFLEKHPDNPLPANFEHLSKNTVNSDTKKIKNGAAY
ARSLDSKDITVTSPIFSEGQIDGYLKVTENRTSTFFTDFAIIIFAIIFYLAVAIQVLKSAQRAYVFRENTVAKIKNIERS
PLTQSYLMNENDDKITTELNKLGEKIQKQALSHTEKKENLYEFIEFFQFPIFIYNNKGKIRRTNASFKNEFSDTENLDIF
SPYADFLNFLVDKILHPDIQEKLFFFEKLGAYYQVRITPLPDLDSRFMVTMNDVSSYRRTVDAHNAFIANVSHELKTPLT
SIKGFAELLETDTVSPSETKNFASIIHKESSRLMSLVQDTLLLTKQNQRIEKKKLSLSALIQNILQSSSPQISEKSLRLE
TQIEEITFKTNEQMVHSIFENLIENAIKYTPAQGQIFVSLHHEQDKIIFSVTDNGPGLSEIQKERIFDRFYRADESRAEV
SGTGLGLAIVEKNVQELHGTIDVVSILGKGTTFTVNL
>Mature_517_residues
MKLKHIMLMTVLYIIATLSLVILSNQNILENDTNRVLKTIDQIQLFLEKHPDNPLPANFEHLSKNTVNSDTKKIKNGAAY
ARSLDSKDITVTSPIFSEGQIDGYLKVTENRTSTFFTDFAIIIFAIIFYLAVAIQVLKSAQRAYVFRENTVAKIKNIERS
PLTQSYLMNENDDKITTELNKLGEKIQKQALSHTEKKENLYEFIEFFQFPIFIYNNKGKIRRTNASFKNEFSDTENLDIF
SPYADFLNFLVDKILHPDIQEKLFFFEKLGAYYQVRITPLPDLDSRFMVTMNDVSSYRRTVDAHNAFIANVSHELKTPLT
SIKGFAELLETDTVSPSETKNFASIIHKESSRLMSLVQDTLLLTKQNQRIEKKKLSLSALIQNILQSSSPQISEKSLRLE
TQIEEITFKTNEQMVHSIFENLIENAIKYTPAQGQIFVSLHHEQDKIIFSVTDNGPGLSEIQKERIFDRFYRADESRAEV
SGTGLGLAIVEKNVQELHGTIDVVSILGKGTTFTVNL

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=277, Percent_Identity=27.4368231046931, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=34.703196347032, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=225, Percent_Identity=29.7777777777778, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI48994928, Length=269, Percent_Identity=28.6245353159851, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790346, Length=213, Percent_Identity=30.9859154929577, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=27.710843373494, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI145693157, Length=218, Percent_Identity=31.651376146789, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=32.8638497652582, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788393, Length=216, Percent_Identity=29.6296296296296, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=28.1818181818182, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082128, Length=218, Percent_Identity=26.1467889908257, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786783, Length=216, Percent_Identity=29.6296296296296, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790551, Length=217, Percent_Identity=28.110599078341, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789808, Length=209, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789149, Length=224, Percent_Identity=29.0178571428571, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=27.2340425531915, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87081816, Length=223, Percent_Identity=25.5605381165919, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788279, Length=214, Percent_Identity=27.5700934579439, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789403, Length=199, Percent_Identity=28.643216080402, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59065; Mature: 59065

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKHIMLMTVLYIIATLSLVILSNQNILENDTNRVLKTIDQIQLFLEKHPDNPLPANFE
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
HLSKNTVNSDTKKIKNGAAYARSLDSKDITVTSPIFSEGQIDGYLKVTENRTSTFFTDFA
HHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHH
IIIFAIIFYLAVAIQVLKSAQRAYVFRENTVAKIKNIERSPLTQSYLMNENDDKITTELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHH
KLGEKIQKQALSHTEKKENLYEFIEFFQFPIFIYNNKGKIRRTNASFKNEFSDTENLDIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCHHHCCCCCCCCCEE
SPYADFLNFLVDKILHPDIQEKLFFFEKLGAYYQVRITPLPDLDSRFMVTMNDVSSYRRT
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEHHHHHHHHH
VDAHNAFIANVSHELKTPLTSIKGFAELLETDTVSPSETKNFASIIHKESSRLMSLVQDT
HHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLLTKQNQRIEKKKLSLSALIQNILQSSSPQISEKSLRLETQIEEITFKTNEQMVHSIFE
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
NLIENAIKYTPAQGQIFVSLHHEQDKIIFSVTDNGPGLSEIQKERIFDRFYRADESRAEV
HHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
SGTGLGLAIVEKNVQELHGTIDVVSILGKGTTFTVNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MKLKHIMLMTVLYIIATLSLVILSNQNILENDTNRVLKTIDQIQLFLEKHPDNPLPANFE
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
HLSKNTVNSDTKKIKNGAAYARSLDSKDITVTSPIFSEGQIDGYLKVTENRTSTFFTDFA
HHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHH
IIIFAIIFYLAVAIQVLKSAQRAYVFRENTVAKIKNIERSPLTQSYLMNENDDKITTELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHH
KLGEKIQKQALSHTEKKENLYEFIEFFQFPIFIYNNKGKIRRTNASFKNEFSDTENLDIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCHHHCCCCCCCCCEE
SPYADFLNFLVDKILHPDIQEKLFFFEKLGAYYQVRITPLPDLDSRFMVTMNDVSSYRRT
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEHHHHHHHHH
VDAHNAFIANVSHELKTPLTSIKGFAELLETDTVSPSETKNFASIIHKESSRLMSLVQDT
HHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLLTKQNQRIEKKKLSLSALIQNILQSSSPQISEKSLRLETQIEEITFKTNEQMVHSIFE
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
NLIENAIKYTPAQGQIFVSLHHEQDKIIFSVTDNGPGLSEIQKERIFDRFYRADESRAEV
HHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
SGTGLGLAIVEKNVQELHGTIDVVSILGKGTTFTVNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]