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The map label for this gene is uxuA [H]

Identifier: 125623704

GI number: 125623704

Start: 826582

End: 827658

Strand: Direct

Name: uxuA [H]

Synonym: llmg_0859

Alternate gene names: 125623704

Gene position: 826582-827658 (Clockwise)

Preceding gene: 125623703

Following gene: 125623705

Centisome position: 32.68

GC content: 39.37

Gene sequence:

>1077_bases
ATGGAAATGACAATGCGTTGGTTTGGTTCAAATGCAGATAAGGTAGAACTTTCTGAAATTGCCCAAGTTCCAGGTGTTAA
AGGAGTTGTTGGAATGATTATGGATATTCCAGCAGGAGAAGTTTGGCCCAAAGAGAGAATTAAGGCCCTTAAAGAGGAAA
TTGAAGCCGCAGGTTTAAGTTTAAAAGTAATTGAATCTGTCAATATTCATGATGATATCAAGATTGGTCTACCGACTCGT
GATAAATATATTGAGAACTATAAAGAAACGATTCGTAATCTTGCTGAATTTGGAATTGAGGTCATTTGTTATAACTTCAT
GCCTGTATTTGACTGGCTGAAATCAGATTTGGATTATCGTTTAGCTGATAATTCGCAAACGATGGCTTTTGTTGCTGAGG
ACATTCCAGAAAATCCTCAAGAAATTATTGACCGTGTTCAAGCAGCCGATGGTGGCTTTTCACTCCCAGGTTGGGAACCA
GAAAGATTGTCAGAAGTGAAAGACCTCTTTGAAGCCTACAAAAATGTCGATGAGCATAAATTGCGCGAAAACTTTGCCTA
CTTTCTAAAAGCAATCATTCCCACTTGTGAAGAAGTTGGAATTAAAATGGCGGTTCACCCAGATGACCCACCATATCCTA
TGTTTGGTCTCCCTCGTGTTGTGAAAAATCGTGAGGATTTAGATTGGATATGTAATGTCGTAGATAGTCCGTCAAACGCG
ATTACGCTTTGTACGGGGTCAATTGCCGAAGATCCAGCCAATAATGTCTATGAAATTATGGCCGAATTTGTCAAAAGAGA
CCGAATTCCTTTTGCACATGTGCGAAATATCAAATTTTTGCCAAGTGGTGAAAAAGATTTTTACGAAGCTCCTCATATGT
CGGAGTATGGTTCCCTTGATATGTATAAAATACTGAAAGCCATGTATGATAATGGTTTTGATGGATATATTCGTCCAGAC
CATGGTCGAATGATTTGGGGAGAAACAGGACGTCCAGGCTATGGCTTATATGACCGAGCACTTGGAGCAAGTTATCTTAA
TGGGCTTTGGGAGGCTCTTGAAAAAAATAAGCAGTAA

Upstream 100 bases:

>100_bases
AGTTTATGTAGGACCTGTCAGCAAAAAATACTGACAATATGAGTCAATTAAAAGAAAGGAAAGTAAATTCTGACACTGAC
AGAATTTGCAATGTATAAAA

Downstream 100 bases:

>100_bases
ATAAAAGTTTTATGAAGGAATCTATTTTAAAGAACTTTTTGTGAAAAAATGTGCGGAGACTTTTCTCCGCTAAATTTAGA
ACGACGGAGTAAGCGTTTCA

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MEMTMRWFGSNADKVELSEIAQVPGVKGVVGMIMDIPAGEVWPKERIKALKEEIEAAGLSLKVIESVNIHDDIKIGLPTR
DKYIENYKETIRNLAEFGIEVICYNFMPVFDWLKSDLDYRLADNSQTMAFVAEDIPENPQEIIDRVQAADGGFSLPGWEP
ERLSEVKDLFEAYKNVDEHKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYPMFGLPRVVKNREDLDWICNVVDSPSNA
ITLCTGSIAEDPANNVYEIMAEFVKRDRIPFAHVRNIKFLPSGEKDFYEAPHMSEYGSLDMYKILKAMYDNGFDGYIRPD
HGRMIWGETGRPGYGLYDRALGASYLNGLWEALEKNKQ

Sequences:

>Translated_358_residues
MEMTMRWFGSNADKVELSEIAQVPGVKGVVGMIMDIPAGEVWPKERIKALKEEIEAAGLSLKVIESVNIHDDIKIGLPTR
DKYIENYKETIRNLAEFGIEVICYNFMPVFDWLKSDLDYRLADNSQTMAFVAEDIPENPQEIIDRVQAADGGFSLPGWEP
ERLSEVKDLFEAYKNVDEHKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYPMFGLPRVVKNREDLDWICNVVDSPSNA
ITLCTGSIAEDPANNVYEIMAEFVKRDRIPFAHVRNIKFLPSGEKDFYEAPHMSEYGSLDMYKILKAMYDNGFDGYIRPD
HGRMIWGETGRPGYGLYDRALGASYLNGLWEALEKNKQ
>Mature_358_residues
MEMTMRWFGSNADKVELSEIAQVPGVKGVVGMIMDIPAGEVWPKERIKALKEEIEAAGLSLKVIESVNIHDDIKIGLPTR
DKYIENYKETIRNLAEFGIEVICYNFMPVFDWLKSDLDYRLADNSQTMAFVAEDIPENPQEIIDRVQAADGGFSLPGWEP
ERLSEVKDLFEAYKNVDEHKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYPMFGLPRVVKNREDLDWICNVVDSPSNA
ITLCTGSIAEDPANNVYEIMAEFVKRDRIPFAHVRNIKFLPSGEKDFYEAPHMSEYGSLDMYKILKAMYDNGFDGYIRPD
HGRMIWGETGRPGYGLYDRALGASYLNGLWEALEKNKQ

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=396, Percent_Identity=38.1313131313131, Blast_Score=255, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 40811; Mature: 40811

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMTMRWFGSNADKVELSEIAQVPGVKGVVGMIMDIPAGEVWPKERIKALKEEIEAAGLS
CCCEEHECCCCCCCEEHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCE
LKVIESVNIHDDIKIGLPTRDKYIENYKETIRNLAEFGIEVICYNFMPVFDWLKSDLDYR
EEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEE
LADNSQTMAFVAEDIPENPQEIIDRVQAADGGFSLPGWEPERLSEVKDLFEAYKNVDEHK
ECCCCCCEEHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
LRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYPMFGLPRVVKNREDLDWICNVVDSPSNA
HHHHHHHHHHHHHCCHHHCCCEEEECCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCCE
ITLCTGSIAEDPANNVYEIMAEFVKRDRIPFAHVRNIKFLPSGEKDFYEAPHMSEYGSLD
EEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCEEECCCCCHHHHCCCCCCCCCCCH
MYKILKAMYDNGFDGYIRPDHGRMIWGETGRPGYGLYDRALGASYLNGLWEALEKNKQ
HHHHHHHHHCCCCCCCEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEMTMRWFGSNADKVELSEIAQVPGVKGVVGMIMDIPAGEVWPKERIKALKEEIEAAGLS
CCCEEHECCCCCCCEEHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCE
LKVIESVNIHDDIKIGLPTRDKYIENYKETIRNLAEFGIEVICYNFMPVFDWLKSDLDYR
EEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEE
LADNSQTMAFVAEDIPENPQEIIDRVQAADGGFSLPGWEPERLSEVKDLFEAYKNVDEHK
ECCCCCCEEHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
LRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYPMFGLPRVVKNREDLDWICNVVDSPSNA
HHHHHHHHHHHHHCCHHHCCCEEEECCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCCE
ITLCTGSIAEDPANNVYEIMAEFVKRDRIPFAHVRNIKFLPSGEKDFYEAPHMSEYGSLD
EEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCEEECCCCCHHHHCCCCCCCCCCCH
MYKILKAMYDNGFDGYIRPDHGRMIWGETGRPGYGLYDRALGASYLNGLWEALEKNKQ
HHHHHHHHHCCCCCCCEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]