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The map label for this gene is pepO [H]

Identifier: 125623558

GI number: 125623558

Start: 689385

End: 691268

Strand: Direct

Name: pepO [H]

Synonym: llmg_0702

Alternate gene names: 125623558

Gene position: 689385-691268 (Clockwise)

Preceding gene: 125623557

Following gene: 125623559

Centisome position: 27.25

GC content: 34.87

Gene sequence:

>1884_bases
ATGACAAGGATTCAAGATGATTTATTCGCTACTGTTAATGCTGAATGGTTAGAAAATGCAGAAATTCCTGCAGACAAACC
AAGAATTTCAGCTTTTGATGAATTAGTACTAAAAAATGAGAAAAATTTGGCTAAAGATTTAGCTGATTTATCACAAAACC
TACCTACTGATAATCCAGAGTTGCTTGAAGCAATCAAATTTTATAATAAAGCAGGAGATTGGCAAGCAAGAGAAAAAGCG
GATTTTTCTGCCGTAAAAAATGAACTTGCTAAAGTTGAAACTTTAAATACTTTTGAAGATTTTAAAAATAATTTGACTCA
ACTCGTTTTCCATTCACAGGCTCCTCTTCCATTTTCTTTTAGTGTTGAACCTGATATGAAAGATGCTATTCACTATTCTC
TTGGATTCTCTGGTCCGGGCTTGATTTTACCTGATACCACTTATTATAATGATGAACACCCTAGAAAAAAAGAATTACTT
GATTTTTGGGCTAAAAATACAAGCGAAATTTTAAAGACATTTGATGTTGAAAATGCAGAAGAGATTGCAAAGTCTGCCCT
TAAATTCGATGCTCTTTTAGTTCCATCAGCAAATACTTCTGAAGAGTGGGCAAAATATGCTGAACTTTATCATCCAATTT
CTACTGACAACTTTGTCAGTAAAGTTAAAAACCTGGATTTAAAATCTTTAATTAAAGATTTAGTAAAAACTGAACCTGAT
AAAGTCATTGTTTATGAAGACCGTTTTTACGAATCATTTGATTCACTTATCAATGAAGAAAATTGGTCACTCATTAAAGC
TTGGATGCTGACTAAAATTGCACGTGGCGCTACTTCTTTCTTCAATGAAGACCTTAGAATTCTTGGTGGAGCTTACGGAC
GTTTCCTTTCAAATGTTCAAGAAGCAAGAAGTCAAGAAAAACATCAACTTGATTTGACTGAGTCTTATTTTAGCCAAGTG
ATTGGTTTATTCTATGGTAAAAAATATTTTGGTGAAGCTGCTAAGGCCGATGTCAAACGGATGGTTACTGCGATGATTAA
AGTTTACCAAGTGCGTTTGTCTAAAAATGAGTGGCTTAGTCAAGAAACAGCTGAAAAAGCCATTGAAAAATTGGATGCTA
TTACTCCTTTCATTGGTTTCCCAGATAAATTGCCTGAAATTTATAGTCGTTTAAAAACAACTTCTGGCTCTCTCTATGAA
GATGCCCTTAAATTCGATAAAATTTTGACTGCTCGAACTTTTGAAAAATTCTCAGAAGATGTTGATAAAACAAGCTGGCA
TATGCCTGCTCATATGGTCAATGCTTATTATAGTCCTGATAGTAATACAATTGTTTTTCCAGCAGCAATTTTGCAAGCTC
CTTTTTACTCTCTTGAACAATCTTCATCACAAAATTACGGTGGAATTGGCGCTGTCATTGCTCATGAAATTTCTCATGCT
TTTGATAACAACGGTGCCCAATTCGATAAAGAAGGAAATTTGAACAAATGGTGGTTAGATGAAGATTATGAAGCTTTTGA
AGAAAAGCAAAAAGAAATGATTGCACTCTTTGACGGCGTAGAAACTGAAGCTGGTCCAGCAAACGGAAAACTCATTGTGT
CAGAAAATATTGCTGACCAAGGAGGAATTACAGCGGCACTGACAGCCGCTAAAGATGAGAAAGACGTTGATTTGAAAGCT
TTCTTTAGTCAGTGGGCTAAGATTTGGCGCATGAAAGCAAGTAAAGAATTCCAACAAATGCTTTTGTCAATGGATGTTCA
TGCACCCGCTAAACTTCGTGCCAATATTCCTCCAACAAATCTCGAAGAATTTTACGAAACTTTTGATGTTAAAGAAACAG
ATAAGATGTATCGTGCACCAGAAAATCGTCTTAAAATTTGGTAA

Upstream 100 bases:

>100_bases
TTTTTTTGTAAAAATACCCTCACTTTAGTTTTCGCAATTCTAAAGTCACAGAAGTTCAAATTTATGATTTGAGCTTCTTT
TATTAAAAAAGGAGTTTGAT

Downstream 100 bases:

>100_bases
TCATTTAATTTATATTAATGATATATTGAAATTGAGTCAAATAATTTAGAAAAAGCACCTATAATCACAAAGTTATGAGT
GCTTTTTCCACTTTTTGATA

Product: endopeptidase O

Products: NA

Alternate protein names: Endopeptidase O [H]

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MTRIQDDLFATVNAEWLENAEIPADKPRISAFDELVLKNEKNLAKDLADLSQNLPTDNPELLEAIKFYNKAGDWQAREKA
DFSAVKNELAKVETLNTFEDFKNNLTQLVFHSQAPLPFSFSVEPDMKDAIHYSLGFSGPGLILPDTTYYNDEHPRKKELL
DFWAKNTSEILKTFDVENAEEIAKSALKFDALLVPSANTSEEWAKYAELYHPISTDNFVSKVKNLDLKSLIKDLVKTEPD
KVIVYEDRFYESFDSLINEENWSLIKAWMLTKIARGATSFFNEDLRILGGAYGRFLSNVQEARSQEKHQLDLTESYFSQV
IGLFYGKKYFGEAAKADVKRMVTAMIKVYQVRLSKNEWLSQETAEKAIEKLDAITPFIGFPDKLPEIYSRLKTTSGSLYE
DALKFDKILTARTFEKFSEDVDKTSWHMPAHMVNAYYSPDSNTIVFPAAILQAPFYSLEQSSSQNYGGIGAVIAHEISHA
FDNNGAQFDKEGNLNKWWLDEDYEAFEEKQKEMIALFDGVETEAGPANGKLIVSENIADQGGITAALTAAKDEKDVDLKA
FFSQWAKIWRMKASKEFQQMLLSMDVHAPAKLRANIPPTNLEEFYETFDVKETDKMYRAPENRLKIW

Sequences:

>Translated_627_residues
MTRIQDDLFATVNAEWLENAEIPADKPRISAFDELVLKNEKNLAKDLADLSQNLPTDNPELLEAIKFYNKAGDWQAREKA
DFSAVKNELAKVETLNTFEDFKNNLTQLVFHSQAPLPFSFSVEPDMKDAIHYSLGFSGPGLILPDTTYYNDEHPRKKELL
DFWAKNTSEILKTFDVENAEEIAKSALKFDALLVPSANTSEEWAKYAELYHPISTDNFVSKVKNLDLKSLIKDLVKTEPD
KVIVYEDRFYESFDSLINEENWSLIKAWMLTKIARGATSFFNEDLRILGGAYGRFLSNVQEARSQEKHQLDLTESYFSQV
IGLFYGKKYFGEAAKADVKRMVTAMIKVYQVRLSKNEWLSQETAEKAIEKLDAITPFIGFPDKLPEIYSRLKTTSGSLYE
DALKFDKILTARTFEKFSEDVDKTSWHMPAHMVNAYYSPDSNTIVFPAAILQAPFYSLEQSSSQNYGGIGAVIAHEISHA
FDNNGAQFDKEGNLNKWWLDEDYEAFEEKQKEMIALFDGVETEAGPANGKLIVSENIADQGGITAALTAAKDEKDVDLKA
FFSQWAKIWRMKASKEFQQMLLSMDVHAPAKLRANIPPTNLEEFYETFDVKETDKMYRAPENRLKIW
>Mature_626_residues
TRIQDDLFATVNAEWLENAEIPADKPRISAFDELVLKNEKNLAKDLADLSQNLPTDNPELLEAIKFYNKAGDWQAREKAD
FSAVKNELAKVETLNTFEDFKNNLTQLVFHSQAPLPFSFSVEPDMKDAIHYSLGFSGPGLILPDTTYYNDEHPRKKELLD
FWAKNTSEILKTFDVENAEEIAKSALKFDALLVPSANTSEEWAKYAELYHPISTDNFVSKVKNLDLKSLIKDLVKTEPDK
VIVYEDRFYESFDSLINEENWSLIKAWMLTKIARGATSFFNEDLRILGGAYGRFLSNVQEARSQEKHQLDLTESYFSQVI
GLFYGKKYFGEAAKADVKRMVTAMIKVYQVRLSKNEWLSQETAEKAIEKLDAITPFIGFPDKLPEIYSRLKTTSGSLYED
ALKFDKILTARTFEKFSEDVDKTSWHMPAHMVNAYYSPDSNTIVFPAAILQAPFYSLEQSSSQNYGGIGAVIAHEISHAF
DNNGAQFDKEGNLNKWWLDEDYEAFEEKQKEMIALFDGVETEAGPANGKLIVSENIADQGGITAALTAAKDEKDVDLKAF
FSQWAKIWRMKASKEFQQMLLSMDVHAPAKLRANIPPTNLEEFYETFDVKETDKMYRAPENRLKIW

Specific function: Endopeptidase with broad substrate specificity for several oligopeptides [H]

COG id: COG3590

COG function: function code O; Predicted metalloendopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M13 family [H]

Homologues:

Organism=Homo sapiens, GI164519140, Length=559, Percent_Identity=26.4758497316637, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI164519136, Length=559, Percent_Identity=26.4758497316637, Blast_Score=219, Evalue=6e-57,
Organism=Homo sapiens, GI164519138, Length=559, Percent_Identity=26.4758497316637, Blast_Score=219, Evalue=7e-57,
Organism=Homo sapiens, GI4503443, Length=559, Percent_Identity=26.4758497316637, Blast_Score=219, Evalue=8e-57,
Organism=Homo sapiens, GI239049391, Length=677, Percent_Identity=27.3264401772526, Blast_Score=206, Evalue=6e-53,
Organism=Homo sapiens, GI82617560, Length=660, Percent_Identity=23.9393939393939, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI153945836, Length=660, Percent_Identity=23.9393939393939, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI153945761, Length=660, Percent_Identity=23.9393939393939, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI153945771, Length=660, Percent_Identity=23.9393939393939, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI157426891, Length=664, Percent_Identity=22.289156626506, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI116256333, Length=330, Percent_Identity=33.6363636363636, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI116256331, Length=330, Percent_Identity=33.6363636363636, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI116256329, Length=330, Percent_Identity=33.6363636363636, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI116256327, Length=330, Percent_Identity=33.6363636363636, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI90403592, Length=690, Percent_Identity=24.2028985507246, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI4557691, Length=357, Percent_Identity=24.3697478991597, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI86562497, Length=683, Percent_Identity=25.9150805270864, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI25148650, Length=683, Percent_Identity=25.4758418740849, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17533333, Length=404, Percent_Identity=26.7326732673267, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI32563993, Length=310, Percent_Identity=29.6774193548387, Blast_Score=168, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17564342, Length=433, Percent_Identity=26.7898383371824, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71987442, Length=319, Percent_Identity=28.5266457680251, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534401, Length=322, Percent_Identity=27.9503105590062, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17570047, Length=598, Percent_Identity=22.2408026755853, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71998977, Length=293, Percent_Identity=26.962457337884, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71998975, Length=293, Percent_Identity=26.962457337884, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988640, Length=236, Percent_Identity=27.1186440677966, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994787, Length=324, Percent_Identity=22.2222222222222, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17533319, Length=352, Percent_Identity=22.7272727272727, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17532485, Length=297, Percent_Identity=24.2424242424242, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24643425, Length=664, Percent_Identity=24.2469879518072, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI45551938, Length=536, Percent_Identity=25.5597014925373, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI45550777, Length=536, Percent_Identity=25.5597014925373, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17737761, Length=403, Percent_Identity=30.0248138957816, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24640050, Length=659, Percent_Identity=23.3687405159332, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24640052, Length=659, Percent_Identity=23.3687405159332, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24650487, Length=369, Percent_Identity=24.1192411924119, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI221474862, Length=365, Percent_Identity=24.9315068493151, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24650765, Length=272, Percent_Identity=26.8382352941176, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281362760, Length=354, Percent_Identity=25.1412429378531, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24650885, Length=348, Percent_Identity=26.4367816091954, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24650889, Length=349, Percent_Identity=24.3553008595989, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355943, Length=359, Percent_Identity=22.2841225626741, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641622, Length=202, Percent_Identity=29.7029702970297, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000718
- InterPro:   IPR018497
- InterPro:   IPR008753 [H]

Pfam domain/function: PF01431 Peptidase_M13; PF05649 Peptidase_M13_N [H]

EC number: NA

Molecular weight: Translated: 71532; Mature: 71401

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIQDDLFATVNAEWLENAEIPADKPRISAFDELVLKNEKNLAKDLADLSQNLPTDNPE
CCCCCCHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHH
LLEAIKFYNKAGDWQAREKADFSAVKNELAKVETLNTFEDFKNNLTQLVFHSQAPLPFSF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
SVEPDMKDAIHYSLGFSGPGLILPDTTYYNDEHPRKKELLDFWAKNTSEILKTFDVENAE
CCCCCHHHHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHH
EIAKSALKFDALLVPSANTSEEWAKYAELYHPISTDNFVSKVKNLDLKSLIKDLVKTEPD
HHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCC
KVIVYEDRFYESFDSLINEENWSLIKAWMLTKIARGATSFFNEDLRILGGAYGRFLSNVQ
EEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARSQEKHQLDLTESYFSQVIGLFYGKKYFGEAAKADVKRMVTAMIKVYQVRLSKNEWLS
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
QETAEKAIEKLDAITPFIGFPDKLPEIYSRLKTTSGSLYEDALKFDKILTARTFEKFSED
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VDKTSWHMPAHMVNAYYSPDSNTIVFPAAILQAPFYSLEQSSSQNYGGIGAVIAHEISHA
HHHHCCCCCHHHHHHEECCCCCEEEEHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHH
FDNNGAQFDKEGNLNKWWLDEDYEAFEEKQKEMIALFDGVETEAGPANGKLIVSENIADQ
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC
GGITAALTAAKDEKDVDLKAFFSQWAKIWRMKASKEFQQMLLSMDVHAPAKLRANIPPTN
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCC
LEEFYETFDVKETDKMYRAPENRLKIW
HHHHHHHCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRIQDDLFATVNAEWLENAEIPADKPRISAFDELVLKNEKNLAKDLADLSQNLPTDNPE
CCCCCHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHH
LLEAIKFYNKAGDWQAREKADFSAVKNELAKVETLNTFEDFKNNLTQLVFHSQAPLPFSF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
SVEPDMKDAIHYSLGFSGPGLILPDTTYYNDEHPRKKELLDFWAKNTSEILKTFDVENAE
CCCCCHHHHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHH
EIAKSALKFDALLVPSANTSEEWAKYAELYHPISTDNFVSKVKNLDLKSLIKDLVKTEPD
HHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCC
KVIVYEDRFYESFDSLINEENWSLIKAWMLTKIARGATSFFNEDLRILGGAYGRFLSNVQ
EEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARSQEKHQLDLTESYFSQVIGLFYGKKYFGEAAKADVKRMVTAMIKVYQVRLSKNEWLS
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
QETAEKAIEKLDAITPFIGFPDKLPEIYSRLKTTSGSLYEDALKFDKILTARTFEKFSED
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VDKTSWHMPAHMVNAYYSPDSNTIVFPAAILQAPFYSLEQSSSQNYGGIGAVIAHEISHA
HHHHCCCCCHHHHHHEECCCCCEEEEHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHH
FDNNGAQFDKEGNLNKWWLDEDYEAFEEKQKEMIALFDGVETEAGPANGKLIVSENIADQ
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC
GGITAALTAAKDEKDVDLKAFFSQWAKIWRMKASKEFQQMLLSMDVHAPAKLRANIPPTN
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCC
LEEFYETFDVKETDKMYRAPENRLKIW
HHHHHHHCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8244921; 11337471 [H]