Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 125623490

GI number: 125623490

Start: 620956

End: 621615

Strand: Direct

Name: coaE [H]

Synonym: llmg_0630

Alternate gene names: 125623490

Gene position: 620956-621615 (Clockwise)

Preceding gene: 125623489

Following gene: 125623491

Centisome position: 24.55

GC content: 32.42

Gene sequence:

>660_bases
ATGATAAAGGTAATTGGATTAACAGGCGGAATTGCGAGTGGGAAATCAACGGTGGTTGATTTTTTGATTTCTGAAGGTTA
TCAAGTAATTGATGCTGACAAAGTTGTTCGTCAGTTGCAAGAACCTGATGGGAAACTTTTTAATGCAATAATGGAAACTT
TCGGTTCAGATTTTACTGACGAAAATGGGAAATTAAACCGAGCAAAATTGAGTGCTTTAGTTTTTTCTGACCCAAATCAA
CGTCAAAAATTATCGAATTTACAAGACGAGATTATTCGTAAAGAATTATATGCTAGACGGGACCAGCTGATAAAAGAGCT
CGGTGAAAAGTCTGTCAGTAACAAAGTTGACGCAGAAGAGCAACCAAAAAAATCGTCAGTAAATCAAATCATATTTATGG
ATATTCCATTATTATTAGAATATCATTATGAAGGTTTTGATGAAATTTGGTTAGTTGCGATACCTGAAAATTTACAAATT
GAAAGATTAATGGCAAGAAATAGCTTTACAGAAGAAGAAGCTAAAAAACGAATTTCTTCACAAATGTCATTGTCAGAAAA
GAAAAAATATGCAGATATAATTTTAGATAATTCTGGAACTATTGATACACTAAAGAAACAAATCCAGCAAGAATTGGCTA
GGATAATCAAAGAGAAATAG

Upstream 100 bases:

>100_bases
TCAGTTCTACTGACAGACTTTTTTTCTATAAATTAATTATAATAGTTAAAAACTATTATTTTTAGTTTAAGAAAAATAAA
ATTTGTGCTAAAATAGATGA

Downstream 100 bases:

>100_bases
GGGTGAATCACACGAAAACAGTTAATTGGAAAAGGAATTTATTTATAACATGGATTGGCTGCTTTTTTGTAGGTTCTTCA
TTTTCACTAGTGATGCCCTT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MIKVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPDGKLFNAIMETFGSDFTDENGKLNRAKLSALVFSDPNQ
RQKLSNLQDEIIRKELYARRDQLIKELGEKSVSNKVDAEEQPKKSSVNQIIFMDIPLLLEYHYEGFDEIWLVAIPENLQI
ERLMARNSFTEEEAKKRISSQMSLSEKKKYADIILDNSGTIDTLKKQIQQELARIIKEK

Sequences:

>Translated_219_residues
MIKVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPDGKLFNAIMETFGSDFTDENGKLNRAKLSALVFSDPNQ
RQKLSNLQDEIIRKELYARRDQLIKELGEKSVSNKVDAEEQPKKSSVNQIIFMDIPLLLEYHYEGFDEIWLVAIPENLQI
ERLMARNSFTEEEAKKRISSQMSLSEKKKYADIILDNSGTIDTLKKQIQQELARIIKEK
>Mature_219_residues
MIKVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPDGKLFNAIMETFGSDFTDENGKLNRAKLSALVFSDPNQ
RQKLSNLQDEIIRKELYARRDQLIKELGEKSVSNKVDAEEQPKKSSVNQIIFMDIPLLLEYHYEGFDEIWLVAIPENLQI
ERLMARNSFTEEEAKKRISSQMSLSEKKKYADIILDNSGTIDTLKKQIQQELARIIKEK

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=207, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI191252795, Length=207, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI110227607, Length=214, Percent_Identity=26.6355140186916, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI110227605, Length=214, Percent_Identity=26.6355140186916, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI110227603, Length=214, Percent_Identity=26.6355140186916, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI110227601, Length=214, Percent_Identity=26.6355140186916, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI205277394, Length=214, Percent_Identity=26.6355140186916, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1786292, Length=211, Percent_Identity=26.0663507109005, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17554944, Length=215, Percent_Identity=32.5581395348837, Blast_Score=119, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI25143409, Length=215, Percent_Identity=29.3023255813954, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=219, Percent_Identity=34.703196347032, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24658602, Length=216, Percent_Identity=31.4814814814815, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24644728, Length=201, Percent_Identity=30.3482587064677, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 24969; Mature: 24969

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPDGKLFNAIMETFGSDFTD
CEEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
ENGKLNRAKLSALVFSDPNQRQKLSNLQDEIIRKELYARRDQLIKELGEKSVSNKVDAEE
CCCCCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QPKKSSVNQIIFMDIPLLLEYHYEGFDEIWLVAIPENLQIERLMARNSFTEEEAKKRISS
CCCHHHHCEEEEEHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHH
QMSLSEKKKYADIILDNSGTIDTLKKQIQQELARIIKEK
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPDGKLFNAIMETFGSDFTD
CEEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
ENGKLNRAKLSALVFSDPNQRQKLSNLQDEIIRKELYARRDQLIKELGEKSVSNKVDAEE
CCCCCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QPKKSSVNQIIFMDIPLLLEYHYEGFDEIWLVAIPENLQIERLMARNSFTEEEAKKRISS
CCCHHHHCEEEEEHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHH
QMSLSEKKKYADIILDNSGTIDTLKKQIQQELARIIKEK
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]