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The map label for this gene is rpoE

Identifier: 125623469

GI number: 125623469

Start: 596618

End: 597184

Strand: Direct

Name: rpoE

Synonym: llmg_0608

Alternate gene names: 125623469

Gene position: 596618-597184 (Clockwise)

Preceding gene: 125623468

Following gene: 125623470

Centisome position: 23.59

GC content: 36.33

Gene sequence:

>567_bases
TTGAAAATTACAGCCTTAGAAGGACAAAAAATCTCAGAACTTTCAATGATTGAAGTTGCCCATGCTTTACTAGAGCAAAA
TGGCAAAGAAATGCAATTTTCTGAAATCATCAGAGCGATTCAAGATTATTTGGAAAAATCAGATGATGAAATTAAAGCTA
GTATTTCTCGTTTTTATACAGAAATCAATACAGACGGTAGTTTCATTCCATTAGGAAATAACGTTTGGGCGCTTCGTTCG
TGGTATGCCATTGATGAAATTGATGAAGAAGTCATCGCTCTTGACGAAATTGAAGACGAAGAAGAAGAAGAAAAACCAGC
TAAAAAACGCAAAAAAGTTAACGCTTTTGGTATCGAAGACGAAATCGACCCAGAAGATGAAGAAGGCACAAAAGAAACAA
CAGAAGAAGATATGTCTTATGATACTCAAGCAGAAGATGAGGATAAAGATGACGTAGCTGCTTATGATGCTGAACTTGCT
GAGGTAGAACTTGATAATGTAGATGAAGAAGTTGACATCGAAGTGGAAGACGATGAAGACGATTCAGACGATACTGATGA
AGACTAA

Upstream 100 bases:

>100_bases
CAAGCCAATTTTGATATACACTATAAAAAGAAAATCTACAGAGGCGTTCGCTTTCTAGGAAACGAGCCCATATTATATTA
GGAAAAGAGAGAGTAAAAAC

Downstream 100 bases:

>100_bases
AACACATAAAAGTGAGGCATCAGCCTCACTTTTATGAATATTTTCTTTTTATTTGTAAAAGTTTAAAAGAACGGTTACAA
TTATAAAAAGAAAAATTTAA

Product: DNA-directed RNA polymerase subunit delta

Products: diphosphate; RNAn+1

Alternate protein names: RNAP delta factor

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKITALEGQKISELSMIEVAHALLEQNGKEMQFSEIIRAIQDYLEKSDDEIKASISRFYTEINTDGSFIPLGNNVWALRS
WYAIDEIDEEVIALDEIEDEEEEEKPAKKRKKVNAFGIEDEIDPEDEEGTKETTEEDMSYDTQAEDEDKDDVAAYDAELA
EVELDNVDEEVDIEVEDDEDDSDDTDED

Sequences:

>Translated_188_residues
MKITALEGQKISELSMIEVAHALLEQNGKEMQFSEIIRAIQDYLEKSDDEIKASISRFYTEINTDGSFIPLGNNVWALRS
WYAIDEIDEEVIALDEIEDEEEEEKPAKKRKKVNAFGIEDEIDPEDEEGTKETTEEDMSYDTQAEDEDKDDVAAYDAELA
EVELDNVDEEVDIEVEDDEDDSDDTDED
>Mature_188_residues
MKITALEGQKISELSMIEVAHALLEQNGKEMQFSEIIRAIQDYLEKSDDEIKASISRFYTEINTDGSFIPLGNNVWALRS
WYAIDEIDEEVIALDEIEDEEEEEKPAKKRKKVNAFGIEDEIDPEDEEGTKETTEEDMSYDTQAEDEDKDDVAAYDAELA
EVELDNVDEEVDIEVEDDEDDSDDTDED

Specific function: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis

COG id: COG3343

COG function: function code K; DNA-directed RNA polymerase, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rpoE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOE_LACLM (A2RIW1)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001031952.1
- STRING:   A2RIW1
- GeneID:   4798525
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_0608
- eggNOG:   COG3343
- HOGENOM:   HBG535252
- OMA:   TDMNTDG
- ProtClustDB:   PRK02363
- HAMAP:   MF_00357
- InterPro:   IPR007759
- PANTHER:   PTHR23405:SF1

Pfam domain/function: PF05066 RNA_pol_delta

EC number: 2.7.7.6

Molecular weight: Translated: 21516; Mature: 21516

Theoretical pI: Translated: 3.56; Mature: 3.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITALEGQKISELSMIEVAHALLEQNGKEMQFSEIIRAIQDYLEKSDDEIKASISRFYT
CEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EINTDGSFIPLGNNVWALRSWYAIDEIDEEVIALDEIEDEEEEEKPAKKRKKVNAFGIED
HHCCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
EIDPEDEEGTKETTEEDMSYDTQAEDEDKDDVAAYDAELAEVELDNVDEEVDIEVEDDED
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
DSDDTDED
CCCCCCCC
>Mature Secondary Structure
MKITALEGQKISELSMIEVAHALLEQNGKEMQFSEIIRAIQDYLEKSDDEIKASISRFYT
CEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EINTDGSFIPLGNNVWALRSWYAIDEIDEEVIALDEIEDEEEEEKPAKKRKKVNAFGIED
HHCCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
EIDPEDEEGTKETTEEDMSYDTQAEDEDKDDVAAYDAELAEVELDNVDEEVDIEVEDDED
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
DSDDTDED
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nucleoside triphosphate; RNAn

Specific reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA