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The map label for this gene is gapA [H]

Identifier: 125623397

GI number: 125623397

Start: 529583

End: 530596

Strand: Direct

Name: gapA [H]

Synonym: llmg_0530

Alternate gene names: 125623397

Gene position: 529583-530596 (Clockwise)

Preceding gene: 125623395

Following gene: 125623400

Centisome position: 20.94

GC content: 40.04

Gene sequence:

>1014_bases
ATGGTAGTTAAAGTTGGTATTAACGGTTTTGGTCGTATTGGACGTTTGGCATTACGTCGAATTCAAGAAGTCGAAGGAGT
TGAAGTAGCGCACATCAATGATTTGACAGACCCAGCAATGCTTGCACATTTACTTAAATATGATACGACTCAAGGACGTT
TTAAAGGAACAGTTGAGGTCAAAGAAGATGGTTTTGATGTCAACGGAAAATTTGTGAAAGTCACTGCTGAACGTAATCCA
GAAGATATTCAATGGGCTGATTCTGGTGTGGAAATTGTTCTTGAAGCGACAGGTTTCTTTGCGACTAAAGAAAAAGCTGA
AAAACATTTGCATCCTGGTGGAGCTAAGAAAGTTTTGATTACAGCACCTGGTGGAAATGATGTCAAAACAGTCGTATTCA
ACACAAATCACACAATTCTTGATGGAAGTGAAACAGTTATTTCTGCCGGTTCTTGTACTACAAATAGTTTAGCACCAATG
GCAGACGCATTAAACAAAAACTTTGGTGTTAAAGGTGGGACAATGACTACTGTCCACTCATACACTGGTGACCAAATGAC
ACTTGATGGTCCACATCGTGGTGGAGATTTCCGCCGTGCGCGTGCTGCAGCTGAAAATATTGTTCCAGCATCAAGTGGAG
CGGCTAAAGCAATTGGTCTTGTTTTGCCTGAGCTTTCTGGTTTGATGAAAGGACATGCTCAACGTGTTTCAACTCCAACA
GGATCAATTACTGAACTTGTTACAGTGCTTGAAAAACATGTCACTGTTGATGAAATCAACGAAGCAATGAAAGCTGCTGC
TGATGAAAGCTTTGGCTATAATGTTGATGAAATTGTGTCATCTGACATTATCGGCATGGCTTACGGTTCACTCTTTGATG
CGACATTGACTGAAGTGACAGACTTAAAAGACGGTGGACAATTAGTTAAAACTGCTGCTTGGTATGACAATGAAATGAGT
TTCACTGCTCAATTAATTCGTACCCTTGAATATTTTGCCAAAATTGCTAAATAA

Upstream 100 bases:

>100_bases
GCAGTTGACCTGAAACAATGTTTCGTATTACGAAGAGTGATATTTGTAGTAGAAAAAGAGAAATTCTCATCATCTAAATA
AAAAAACGGAGGACTACATC

Downstream 100 bases:

>100_bases
AAATTTATGATTATTATTTCCTGAAGAATTTGTCAGTAGAAATTGCTGACAAAAGCTTTGGGATATCCGTAAACTGCTAA
GGCAAGTAAGGCTAATCTAA

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MVVKVGINGFGRIGRLALRRIQEVEGVEVAHINDLTDPAMLAHLLKYDTTQGRFKGTVEVKEDGFDVNGKFVKVTAERNP
EDIQWADSGVEIVLEATGFFATKEKAEKHLHPGGAKKVLITAPGGNDVKTVVFNTNHTILDGSETVISAGSCTTNSLAPM
ADALNKNFGVKGGTMTTVHSYTGDQMTLDGPHRGGDFRRARAAAENIVPASSGAAKAIGLVLPELSGLMKGHAQRVSTPT
GSITELVTVLEKHVTVDEINEAMKAAADESFGYNVDEIVSSDIIGMAYGSLFDATLTEVTDLKDGGQLVKTAAWYDNEMS
FTAQLIRTLEYFAKIAK

Sequences:

>Translated_337_residues
MVVKVGINGFGRIGRLALRRIQEVEGVEVAHINDLTDPAMLAHLLKYDTTQGRFKGTVEVKEDGFDVNGKFVKVTAERNP
EDIQWADSGVEIVLEATGFFATKEKAEKHLHPGGAKKVLITAPGGNDVKTVVFNTNHTILDGSETVISAGSCTTNSLAPM
ADALNKNFGVKGGTMTTVHSYTGDQMTLDGPHRGGDFRRARAAAENIVPASSGAAKAIGLVLPELSGLMKGHAQRVSTPT
GSITELVTVLEKHVTVDEINEAMKAAADESFGYNVDEIVSSDIIGMAYGSLFDATLTEVTDLKDGGQLVKTAAWYDNEMS
FTAQLIRTLEYFAKIAK
>Mature_337_residues
MVVKVGINGFGRIGRLALRRIQEVEGVEVAHINDLTDPAMLAHLLKYDTTQGRFKGTVEVKEDGFDVNGKFVKVTAERNP
EDIQWADSGVEIVLEATGFFATKEKAEKHLHPGGAKKVLITAPGGNDVKTVVFNTNHTILDGSETVISAGSCTTNSLAPM
ADALNKNFGVKGGTMTTVHSYTGDQMTLDGPHRGGDFRRARAAAENIVPASSGAAKAIGLVLPELSGLMKGHAQRVSTPT
GSITELVTVLEKHVTVDEINEAMKAAADESFGYNVDEIVSSDIIGMAYGSLFDATLTEVTDLKDGGQLVKTAAWYDNEMS
FTAQLIRTLEYFAKIAK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=42.2619047619048, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI7657116, Length=334, Percent_Identity=40.7185628742515, Blast_Score=243, Evalue=1e-64,
Organism=Escherichia coli, GI1788079, Length=339, Percent_Identity=46.0176991150442, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI1789295, Length=344, Percent_Identity=36.3372093023256, Blast_Score=214, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17568413, Length=340, Percent_Identity=44.4117647058823, Blast_Score=260, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI32566163, Length=340, Percent_Identity=44.4117647058823, Blast_Score=260, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI17534677, Length=340, Percent_Identity=43.8235294117647, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17534679, Length=340, Percent_Identity=43.8235294117647, Blast_Score=254, Evalue=6e-68,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=41.2979351032448, Blast_Score=258, Evalue=7e-70,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=41.2979351032448, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=40.7079646017699, Blast_Score=243, Evalue=4e-65,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=44.1441441441441, Blast_Score=252, Evalue=2e-67,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=44.1441441441441, Blast_Score=252, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=43.5435435435435, Blast_Score=252, Evalue=2e-67,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=43.5435435435435, Blast_Score=252, Evalue=2e-67,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=39.4578313253012, Blast_Score=233, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36043; Mature: 36043

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVKVGINGFGRIGRLALRRIQEVEGVEVAHINDLTDPAMLAHLLKYDTTQGRFKGTVEV
CEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEE
KEDGFDVNGKFVKVTAERNPEDIQWADSGVEIVLEATGFFATKEKAEKHLHPGGAKKVLI
ECCCCCCCCEEEEEEECCCCCCCEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEEE
TAPGGNDVKTVVFNTNHTILDGSETVISAGSCTTNSLAPMADALNKNFGVKGGTMTTVHS
ECCCCCCEEEEEEECCCEEECCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEE
YTGDQMTLDGPHRGGDFRRARAAAENIVPASSGAAKAIGLVLPELSGLMKGHAQRVSTPT
CCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GSITELVTVLEKHVTVDEINEAMKAAADESFGYNVDEIVSSDIIGMAYGSLFDATLTEVT
CHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DLKDGGQLVKTAAWYDNEMSFTAQLIRTLEYFAKIAK
CCCCCCHHEEEHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVKVGINGFGRIGRLALRRIQEVEGVEVAHINDLTDPAMLAHLLKYDTTQGRFKGTVEV
CEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEE
KEDGFDVNGKFVKVTAERNPEDIQWADSGVEIVLEATGFFATKEKAEKHLHPGGAKKVLI
ECCCCCCCCEEEEEEECCCCCCCEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEEE
TAPGGNDVKTVVFNTNHTILDGSETVISAGSCTTNSLAPMADALNKNFGVKGGTMTTVHS
ECCCCCCEEEEEEECCCEEECCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEE
YTGDQMTLDGPHRGGDFRRARAAAENIVPASSGAAKAIGLVLPELSGLMKGHAQRVSTPT
CCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GSITELVTVLEKHVTVDEINEAMKAAADESFGYNVDEIVSSDIIGMAYGSLFDATLTEVT
CHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DLKDGGQLVKTAAWYDNEMSFTAQLIRTLEYFAKIAK
CCCCCCHHEEEHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7773380; 11337471 [H]