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The map label for this gene is glpT [H]

Identifier: 125623390

GI number: 125623390

Start: 522209

End: 523588

Strand: Direct

Name: glpT [H]

Synonym: llmg_0523

Alternate gene names: 125623390

Gene position: 522209-523588 (Clockwise)

Preceding gene: 125623389

Following gene: 125623391

Centisome position: 20.64

GC content: 40.29

Gene sequence:

>1380_bases
ATGCTTGGATTCTTAAAACCAGCTCCAGATGCAGAGCAAAAAATCTCAGAGGAAAAAGTTCCCCGTTTATATAAAATTTG
GCAAACTCGGGTTCTAATTTCGACAGCAATGGTTTACATTGGTTATTATATTATTCGATTGATTTTCACCGTTCAGCAAA
ATGATATCTCAAAAGCTTATGGCTTTTCGATGGGACAGATTGGGACAATCCTCTCCATGTTTGGGATTGGCTATGGAATC
TCAAAACTTATCATGGGAACTCTAGCTGATAGGGCCAACCCCAATCGCTATGTGGCAACGGGTTTGATTGTTTCATCAAT
CATCAATGCGCTTTATGGGACGACTCAAAGTTTTGGAATGATTGTTTTTCTGATGTTGCTTAATTCAGTCATGCAAGGCA
TGGGGGCTGCGGCCTGTCAGCGTTTGGTCGGCTTATGGTTTGGTCGCAAAGGGAAAGGCTCAATTATGGCGCGTGGAACG
GCATTTTCCATCTGGTCATCGGCTCACAATGCAGGAGCGTTCATGTGTGTGGCTGTCATTAATTTATCTGCTTTGTTTTT
CGGCGCTTCGCTTCAATGGAGTTTTTGGACAGCATCAATTGTCTCGATTATCATTGCTGTTATCGTATTATTTCTTGGCT
CGGATCGTCCAACAACCAAAGGATTGCCTACGATTGAAGAATATTCTGGGGATAAAGTGGTCATTAAAGATGGAGAAGTT
GTCGAAGGTGATGTTTCTGACGAAAATGTCTTTAAGATATTCTTTGAATATATTGTCAAAAACAAACTCGTTTGGGCAGT
TATCCTGACTTCACTCTCAATTTATGTGGTGCGTTATGGCATCATGAGTTGGATTCCCAACTACTTGGTCAATGTCAAAG
GATTTGATAATTCAACGGCAAAATGGCTGACAGGAATTTTTGAACTGGCGGCTGTCCCTGGTGTTATTATCATTGGATTT
ATTACTGATTTGCTCAGAGGACGTCGGGCCATTATGGTTTTGATTTCACTGATCGCCATGCTTGCTTGTCTAATTACTTA
TTTTGCGGCAACAAACCACACTTTGATTATTATTGTCTTATTAATTATGGGAACATTTATCTATGCACCGGCGACGATTG
TCGGTTTGATGGTCAATGAAGCCGTACCGAAATTTGCCAATGGAATGTCAACAGGAACAATGGGATTCTGTCAGTATATC
ATTGGGGAAGTGACGGCAACCTTGGTCATTGGATGGGTTGTTCAATCTTATGGCTGGTCAGCTGGAAATATCATTGTTTA
TGCTTTTGCGGGTATTGCCATTTTGGCTTCAATCTATATCTTAATTTATCAAAATAAATTGTATAAGAAAATTGATAATG
CTGCTGAGATTGCAGAATAA

Upstream 100 bases:

>100_bases
ATTATTTAAGAATAAATTCCTGAAATTATAGTAAAATCAGGAATTTATTTCAATGGAGAGTAAGTTATAATTAATTTATC
AAAATGAAAGGGGATTCAAC

Downstream 100 bases:

>100_bases
AAAAATTACTGACAATTTTGTCAGTAATTTTTTTAATAGATGGTATTCTTTGAAACTATAGAGTAATTATTGGATAACGT
ATAGATAAATTTTTGAAACA

Product: glycerol-3-phosphatase transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLGFLKPAPDAEQKISEEKVPRLYKIWQTRVLISTAMVYIGYYIIRLIFTVQQNDISKAYGFSMGQIGTILSMFGIGYGI
SKLIMGTLADRANPNRYVATGLIVSSIINALYGTTQSFGMIVFLMLLNSVMQGMGAAACQRLVGLWFGRKGKGSIMARGT
AFSIWSSAHNAGAFMCVAVINLSALFFGASLQWSFWTASIVSIIIAVIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEV
VEGDVSDENVFKIFFEYIVKNKLVWAVILTSLSIYVVRYGIMSWIPNYLVNVKGFDNSTAKWLTGIFELAAVPGVIIIGF
ITDLLRGRRAIMVLISLIAMLACLITYFAATNHTLIIIVLLIMGTFIYAPATIVGLMVNEAVPKFANGMSTGTMGFCQYI
IGEVTATLVIGWVVQSYGWSAGNIIVYAFAGIAILASIYILIYQNKLYKKIDNAAEIAE

Sequences:

>Translated_459_residues
MLGFLKPAPDAEQKISEEKVPRLYKIWQTRVLISTAMVYIGYYIIRLIFTVQQNDISKAYGFSMGQIGTILSMFGIGYGI
SKLIMGTLADRANPNRYVATGLIVSSIINALYGTTQSFGMIVFLMLLNSVMQGMGAAACQRLVGLWFGRKGKGSIMARGT
AFSIWSSAHNAGAFMCVAVINLSALFFGASLQWSFWTASIVSIIIAVIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEV
VEGDVSDENVFKIFFEYIVKNKLVWAVILTSLSIYVVRYGIMSWIPNYLVNVKGFDNSTAKWLTGIFELAAVPGVIIIGF
ITDLLRGRRAIMVLISLIAMLACLITYFAATNHTLIIIVLLIMGTFIYAPATIVGLMVNEAVPKFANGMSTGTMGFCQYI
IGEVTATLVIGWVVQSYGWSAGNIIVYAFAGIAILASIYILIYQNKLYKKIDNAAEIAE
>Mature_459_residues
MLGFLKPAPDAEQKISEEKVPRLYKIWQTRVLISTAMVYIGYYIIRLIFTVQQNDISKAYGFSMGQIGTILSMFGIGYGI
SKLIMGTLADRANPNRYVATGLIVSSIINALYGTTQSFGMIVFLMLLNSVMQGMGAAACQRLVGLWFGRKGKGSIMARGT
AFSIWSSAHNAGAFMCVAVINLSALFFGASLQWSFWTASIVSIIIAVIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEV
VEGDVSDENVFKIFFEYIVKNKLVWAVILTSLSIYVVRYGIMSWIPNYLVNVKGFDNSTAKWLTGIFELAAVPGVIIIGF
ITDLLRGRRAIMVLISLIAMLACLITYFAATNHTLIIIVLLIMGTFIYAPATIVGLMVNEAVPKFANGMSTGTMGFCQYI
IGEVTATLVIGWVVQSYGWSAGNIIVYAFAGIAILASIYILIYQNKLYKKIDNAAEIAE

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI46361976, Length=329, Percent_Identity=24.3161094224924, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI256219598, Length=407, Percent_Identity=19.9017199017199, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4503847, Length=407, Percent_Identity=19.9017199017199, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI256219483, Length=407, Percent_Identity=19.9017199017199, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI256219543, Length=429, Percent_Identity=20.2797202797203, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1788573, Length=464, Percent_Identity=29.5258620689655, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI87082310, Length=445, Percent_Identity=27.8651685393258, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI2367259, Length=428, Percent_Identity=29.9065420560748, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87082320, Length=410, Percent_Identity=22.9268292682927, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367379, Length=407, Percent_Identity=21.1302211302211, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133901856, Length=349, Percent_Identity=25.7879656160458, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI133901854, Length=349, Percent_Identity=25.7879656160458, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17542316, Length=411, Percent_Identity=22.8710462287105, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50194; Mature: 50194

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGFLKPAPDAEQKISEEKVPRLYKIWQTRVLISTAMVYIGYYIIRLIFTVQQNDISKAY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFSMGQIGTILSMFGIGYGISKLIMGTLADRANPNRYVATGLIVSSIINALYGTTQSFGM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
IVFLMLLNSVMQGMGAAACQRLVGLWFGRKGKGSIMARGTAFSIWSSAHNAGAFMCVAVI
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHCCCCCHHHHHHHHH
NLSALFFGASLQWSFWTASIVSIIIAVIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEECCCE
VEGDVSDENVFKIFFEYIVKNKLVWAVILTSLSIYVVRYGIMSWIPNYLVNVKGFDNSTA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHH
KWLTGIFELAAVPGVIIIGFITDLLRGRRAIMVLISLIAMLACLITYFAATNHTLIIIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LIMGTFIYAPATIVGLMVNEAVPKFANGMSTGTMGFCQYIIGEVTATLVIGWVVQSYGWS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGNIIVYAFAGIAILASIYILIYQNKLYKKIDNAAEIAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MLGFLKPAPDAEQKISEEKVPRLYKIWQTRVLISTAMVYIGYYIIRLIFTVQQNDISKAY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFSMGQIGTILSMFGIGYGISKLIMGTLADRANPNRYVATGLIVSSIINALYGTTQSFGM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
IVFLMLLNSVMQGMGAAACQRLVGLWFGRKGKGSIMARGTAFSIWSSAHNAGAFMCVAVI
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHCCCCCHHHHHHHHH
NLSALFFGASLQWSFWTASIVSIIIAVIVLFLGSDRPTTKGLPTIEEYSGDKVVIKDGEV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEECCCE
VEGDVSDENVFKIFFEYIVKNKLVWAVILTSLSIYVVRYGIMSWIPNYLVNVKGFDNSTA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHH
KWLTGIFELAAVPGVIIIGFITDLLRGRRAIMVLISLIAMLACLITYFAATNHTLIIIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LIMGTFIYAPATIVGLMVNEAVPKFANGMSTGTMGFCQYIIGEVTATLVIGWVVQSYGWS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGNIIVYAFAGIAILASIYILIYQNKLYKKIDNAAEIAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 9714837 [H]