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The map label for this gene is ponA [H]

Identifier: 125623378

GI number: 125623378

Start: 502886

End: 504967

Strand: Reverse

Name: ponA [H]

Synonym: llmg_0511

Alternate gene names: 125623378

Gene position: 504967-502886 (Counterclockwise)

Preceding gene: 125623379

Following gene: 125623377

Centisome position: 19.96

GC content: 39.72

Gene sequence:

>2082_bases
GTGAGGTACAGTAAAATTTCTACTAAATCTAAGAAAAATAAACAAAATAAACGGGCAAAACGCGGTTCTGCTAAATCAAA
ATGGTGGACAGCTGTTAAATTATTTTTGATTGTCTTCTTTTCATTAATTATCTTGGGGCTAGCTGCCGGTGGCGCTGTTT
TTGTTTATTACTCCAAGGATGCACCCGCTCTCAATTTAGATAAGCTTGAATCTACTCCTTCTCCTAAAGTTTACGATTCA
AAAGAACAGCTTGTTGCAACTTTAGGGGCAGAGCAAAGAAATTTAGTTAAAACAGACAATATTCCGGTTATGCTGGTTAA
TGCTGTTACTTCTATTGAAGACCATCGTTTTTTCAACACACGTGGAATTGACCCGATACGGATTGCCGGTGCCTTCGTCA
ACAACTTAAAAGGTGGTTCTTTAAACGGGGGTTCTACCCTTGATATGCAGTTGATTAAACTTTCTTTTTTCTCAACAGAT
GAATCGGACCAGACTTTGAGCGTCAAAGTTCAAGAAGCTTGGATGGCTCTAAAATTGGACCAAAAATGGACCAAAGAACA
AATTTTTACTGCTTATGTCAATAAGGTAAATATGGCAAATGGGTATTACGGGATGGGAACTGCTGCGCAAGCCTATTACG
GAAAAGATTTAACAGAACTTTCAATTGCTCAACTGGCTCTTCTTGCTGGAATGCCTCAAGCACCTAATACTTATAACCCT
TACACTAACGCAACTTCTGCCAAATGGCGCCGTGACATGGTTATTCGCTCAATGCGTCGTTATAATAAAATTACGGCTGA
AGAAGAGAAAACGGCGCTAGCTACTCCAATTGATGATGGTCTTCAACCTTTGCAACAAAGCGTTACGATTCCTAGTTATG
CTGATAACTTCCTCAAACAAGCTATAGCACAAGCCAAGACCTTAGCTGGTAATGATATTTTAAACGAAGGGGTTAAAATT
TATACAACCCTTGATACTACAGCACAACAAAATCTATATAATATTGTTAATAGCGGTAATTATATTACCTACCCAGATGA
TACACTGCAAGTAGCTTCAACGGTCACTGATGTTAAAACTGGCGCTGTAATCGCACAAATCGGTGGACGTAATCAACCAA
CCGATGTCACTTTTGGTTTCAATCAGGCGGTTCAAACAGACCGAGATTGGGGTTCAACGATGAAACCAATTGTTGACTAT
GGCCCCGCTTTTGAAAATAATATCTATACTTCAACGAATGATTATGTTTCTGACTCCCCAACGACTTATCCAAACGGAAC
GCCTTTGAAAAACTGGGATAATACCTATTTTGGTTCAATGACTGTTAAGAGCGCATTGGCCCTTTCCAGAAATATTCCAG
CTGTTAAAACTTTAATTAATGTTGGTTTAGATAATTCTAGTAAATTTGTGGATGGTTTAGGTATTAATTTGAACCCGCTG
CAATACTCCAATGCTATCTCTAGTAATACTAATACAAAAAATGGTGGGGCAAGTTCTGAGAAAATGGCTGCGGCTTACGC
TGCTTTCTCAAATGGTGGTATCTACACTAAACCTTACTATGTTTCTAAAGTTGTTTTCCCCGACGGGCGAACAGTTGAAT
ACAAACCAGTTCGTTCACGGGCAATGCAAGCTTCAACAGCTTATATTATGACTAATATTCTCCAAAGTGTTTTAACATTA
CCACTTTCTGAATCTGTCGGTTCATACGCTGCTGTTCCGGGCTTGCCTGCAGCTGGTAAAACAGGGACTTCTAATTATAC
TGATAGTGAAATGGACCAAATTACTGAAAAATACGGCTCACTCCCTGGAATGGTTTCTCCTGATGAAAACTTCGTTGGTT
ATACTCCTCAGTATTCAATGGCCGTTTGGACTGGTTATTCAAATCGAATGACTCCAATATATGGTACAAGTACTCAAATT
GCCACAAAAGTCTTTTCATCAATGATGACTCAACTCAATCCTGACCCGTCTGCTGTTGCAACTTGGACAGCGCCTGAGGG
CGTCGCTCAACAAGGATCTGCTCTGGTTAAAACAGATAGTTCTGGTCAAACCGTTACACAATCTTCTGCTAATGGTGGCT
AA

Upstream 100 bases:

>100_bases
TTAAAGTCAATCCCACTCGCTTATATTCGCGAAAATGGCTATAAAATTGAAACGAACCACATTCCTAGAATTCCATATCT
AGAAATTGTGAATAAACTTT

Downstream 100 bases:

>100_bases
ATGATAATTGAAAAAATTGTTAATAAAATTGCTCAGGAAAATACCTATGTCCTGAGCAATTCTACTTCATACCTTATTAT
TGACCCAGGAAGTGATTCAT

Product: penicillin-binding protein 1a

Products: NA

Alternate protein names: PBP-1A [H]

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MRYSKISTKSKKNKQNKRAKRGSAKSKWWTAVKLFLIVFFSLIILGLAAGGAVFVYYSKDAPALNLDKLESTPSPKVYDS
KEQLVATLGAEQRNLVKTDNIPVMLVNAVTSIEDHRFFNTRGIDPIRIAGAFVNNLKGGSLNGGSTLDMQLIKLSFFSTD
ESDQTLSVKVQEAWMALKLDQKWTKEQIFTAYVNKVNMANGYYGMGTAAQAYYGKDLTELSIAQLALLAGMPQAPNTYNP
YTNATSAKWRRDMVIRSMRRYNKITAEEEKTALATPIDDGLQPLQQSVTIPSYADNFLKQAIAQAKTLAGNDILNEGVKI
YTTLDTTAQQNLYNIVNSGNYITYPDDTLQVASTVTDVKTGAVIAQIGGRNQPTDVTFGFNQAVQTDRDWGSTMKPIVDY
GPAFENNIYTSTNDYVSDSPTTYPNGTPLKNWDNTYFGSMTVKSALALSRNIPAVKTLINVGLDNSSKFVDGLGINLNPL
QYSNAISSNTNTKNGGASSEKMAAAYAAFSNGGIYTKPYYVSKVVFPDGRTVEYKPVRSRAMQASTAYIMTNILQSVLTL
PLSESVGSYAAVPGLPAAGKTGTSNYTDSEMDQITEKYGSLPGMVSPDENFVGYTPQYSMAVWTGYSNRMTPIYGTSTQI
ATKVFSSMMTQLNPDPSAVATWTAPEGVAQQGSALVKTDSSGQTVTQSSANGG

Sequences:

>Translated_693_residues
MRYSKISTKSKKNKQNKRAKRGSAKSKWWTAVKLFLIVFFSLIILGLAAGGAVFVYYSKDAPALNLDKLESTPSPKVYDS
KEQLVATLGAEQRNLVKTDNIPVMLVNAVTSIEDHRFFNTRGIDPIRIAGAFVNNLKGGSLNGGSTLDMQLIKLSFFSTD
ESDQTLSVKVQEAWMALKLDQKWTKEQIFTAYVNKVNMANGYYGMGTAAQAYYGKDLTELSIAQLALLAGMPQAPNTYNP
YTNATSAKWRRDMVIRSMRRYNKITAEEEKTALATPIDDGLQPLQQSVTIPSYADNFLKQAIAQAKTLAGNDILNEGVKI
YTTLDTTAQQNLYNIVNSGNYITYPDDTLQVASTVTDVKTGAVIAQIGGRNQPTDVTFGFNQAVQTDRDWGSTMKPIVDY
GPAFENNIYTSTNDYVSDSPTTYPNGTPLKNWDNTYFGSMTVKSALALSRNIPAVKTLINVGLDNSSKFVDGLGINLNPL
QYSNAISSNTNTKNGGASSEKMAAAYAAFSNGGIYTKPYYVSKVVFPDGRTVEYKPVRSRAMQASTAYIMTNILQSVLTL
PLSESVGSYAAVPGLPAAGKTGTSNYTDSEMDQITEKYGSLPGMVSPDENFVGYTPQYSMAVWTGYSNRMTPIYGTSTQI
ATKVFSSMMTQLNPDPSAVATWTAPEGVAQQGSALVKTDSSGQTVTQSSANGG
>Mature_693_residues
MRYSKISTKSKKNKQNKRAKRGSAKSKWWTAVKLFLIVFFSLIILGLAAGGAVFVYYSKDAPALNLDKLESTPSPKVYDS
KEQLVATLGAEQRNLVKTDNIPVMLVNAVTSIEDHRFFNTRGIDPIRIAGAFVNNLKGGSLNGGSTLDMQLIKLSFFSTD
ESDQTLSVKVQEAWMALKLDQKWTKEQIFTAYVNKVNMANGYYGMGTAAQAYYGKDLTELSIAQLALLAGMPQAPNTYNP
YTNATSAKWRRDMVIRSMRRYNKITAEEEKTALATPIDDGLQPLQQSVTIPSYADNFLKQAIAQAKTLAGNDILNEGVKI
YTTLDTTAQQNLYNIVNSGNYITYPDDTLQVASTVTDVKTGAVIAQIGGRNQPTDVTFGFNQAVQTDRDWGSTMKPIVDY
GPAFENNIYTSTNDYVSDSPTTYPNGTPLKNWDNTYFGSMTVKSALALSRNIPAVKTLINVGLDNSSKFVDGLGINLNPL
QYSNAISSNTNTKNGGASSEKMAAAYAAFSNGGIYTKPYYVSKVVFPDGRTVEYKPVRSRAMQASTAYIMTNILQSVLTL
PLSESVGSYAAVPGLPAAGKTGTSNYTDSEMDQITEKYGSLPGMVSPDENFVGYTPQYSMAVWTGYSNRMTPIYGTSTQI
ATKVFSSMMTQLNPDPSAVATWTAPEGVAQQGSALVKTDSSGQTVTQSSANGG

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1788867, Length=546, Percent_Identity=28.3882783882784, Blast_Score=155, Evalue=9e-39,
Organism=Escherichia coli, GI1786343, Length=608, Percent_Identity=28.6184210526316, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI87082258, Length=304, Percent_Identity=30.2631578947368, Blast_Score=146, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.2.-; 3.4.-.-

Molecular weight: Translated: 75265; Mature: 75265

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYSKISTKSKKNKQNKRAKRGSAKSKWWTAVKLFLIVFFSLIILGLAAGGAVFVYYSKD
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
APALNLDKLESTPSPKVYDSKEQLVATLGAEQRNLVKTDNIPVMLVNAVTSIEDHRFFNT
CCCCCHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEECCCCCEEEEEHHHHHHHCCEECC
RGIDPIRIAGAFVNNLKGGSLNGGSTLDMQLIKLSFFSTDESDQTLSVKVQEAWMALKLD
CCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEEHHHEEEECC
QKWTKEQIFTAYVNKVNMANGYYGMGTAAQAYYGKDLTELSIAQLALLAGMPQAPNTYNP
HHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
YTNATSAKWRRDMVIRSMRRYNKITAEEEKTALATPIDDGLQPLQQSVTIPSYADNFLKQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCEECCCHHHHHHHHHHHCCCCHHHHHHHHH
AIAQAKTLAGNDILNEGVKIYTTLDTTAQQNLYNIVNSGNYITYPDDTLQVASTVTDVKT
HHHHHHHHCCCHHHHCCEEEEEEECCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHC
GAVIAQIGGRNQPTDVTFGFNQAVQTDRDWGSTMKPIVDYGPAFENNIYTSTNDYVSDSP
CEEEEECCCCCCCCEEEECCCHHHCCCCCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCC
TTYPNGTPLKNWDNTYFGSMTVKSALALSRNIPAVKTLINVGLDNSSKFVDGLGINLNPL
CCCCCCCCCCCCCCCEECCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCC
QYSNAISSNTNTKNGGASSEKMAAAYAAFSNGGIYTKPYYVSKVVFPDGRTVEYKPVRSR
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCEEEECHHHHH
AMQASTAYIMTNILQSVLTLPLSESVGSYAAVPGLPAAGKTGTSNYTDSEMDQITEKYGS
HHHHHHHHHHHHHHHHHHHCCHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
LPGMVSPDENFVGYTPQYSMAVWTGYSNRMTPIYGTSTQIATKVFSSMMTQLNPDPSAVA
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEE
TWTAPEGVAQQGSALVKTDSSGQTVTQSSANGG
EECCCCCHHHCCCEEEEECCCCCEEECCCCCCC
>Mature Secondary Structure
MRYSKISTKSKKNKQNKRAKRGSAKSKWWTAVKLFLIVFFSLIILGLAAGGAVFVYYSKD
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
APALNLDKLESTPSPKVYDSKEQLVATLGAEQRNLVKTDNIPVMLVNAVTSIEDHRFFNT
CCCCCHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEECCCCCEEEEEHHHHHHHCCEECC
RGIDPIRIAGAFVNNLKGGSLNGGSTLDMQLIKLSFFSTDESDQTLSVKVQEAWMALKLD
CCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEEHHHEEEECC
QKWTKEQIFTAYVNKVNMANGYYGMGTAAQAYYGKDLTELSIAQLALLAGMPQAPNTYNP
HHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
YTNATSAKWRRDMVIRSMRRYNKITAEEEKTALATPIDDGLQPLQQSVTIPSYADNFLKQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCEECCCHHHHHHHHHHHCCCCHHHHHHHHH
AIAQAKTLAGNDILNEGVKIYTTLDTTAQQNLYNIVNSGNYITYPDDTLQVASTVTDVKT
HHHHHHHHCCCHHHHCCEEEEEEECCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHC
GAVIAQIGGRNQPTDVTFGFNQAVQTDRDWGSTMKPIVDYGPAFENNIYTSTNDYVSDSP
CEEEEECCCCCCCCEEEECCCHHHCCCCCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCC
TTYPNGTPLKNWDNTYFGSMTVKSALALSRNIPAVKTLINVGLDNSSKFVDGLGINLNPL
CCCCCCCCCCCCCCCEECCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCC
QYSNAISSNTNTKNGGASSEKMAAAYAAFSNGGIYTKPYYVSKVVFPDGRTVEYKPVRSR
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCEEEECHHHHH
AMQASTAYIMTNILQSVLTLPLSESVGSYAAVPGLPAAGKTGTSNYTDSEMDQITEKYGS
HHHHHHHHHHHHHHHHHHHCCHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
LPGMVSPDENFVGYTPQYSMAVWTGYSNRMTPIYGTSTQIATKVFSSMMTQLNPDPSAVA
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEE
TWTAPEGVAQQGSALVKTDSSGQTVTQSSANGG
EECCCCCHHHCCCEEEEECCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1624444 [H]