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The map label for this gene is recU

Identifier: 125623379

GI number: 125623379

Start: 504954

End: 505595

Strand: Reverse

Name: recU

Synonym: llmg_0512

Alternate gene names: 125623379

Gene position: 505595-504954 (Counterclockwise)

Preceding gene: 125623396

Following gene: 125623378

Centisome position: 19.99

GC content: 35.98

Gene sequence:

>642_bases
ATGGTTAATTATCCTAATGGAAGGTCGCAGTCTTATAGCGCTGTTCCTAAAAAACAAAAAACACTGACAGGGCTGTCAGT
AGCTAAAAAGGGTGCTCCAAAATCTAAAAGTCTTGTTGCTTTCGGAAAGCGAGGGATGAATTTTGAAGCAGAAATCAATG
CAACAAATGATTACTATCTCTCACGCGGTCTTGCCGTTATTCATAAAAAACCAACACCGATACAGATTGTTAAAGTAGAC
TATCCACAACGAAGTCGTGCAAAAATTACAGAAGCTTATTTTAGACAAGCCTCTACGACTGACTATTCTGGAGTCTATAA
AGGTCATTATGTTGATTTTGAAGCAAAAGAAACACACCAAAAAACGGTTTTTCCTTTAAAAAATTTCCATGAACATCAAA
TTGTTCACATGAGTAATGTTCTCGCTCAGCGAGGAATTGCTTTTATATTGTTACATTTTGCGGCTCTAGACGAGACATAT
CTTCTCCCGTCTTCCTATTTAATTACGTTTTATTACGAAAAAAACGGTTTAAAGTCAATCCCACTCGCTTATATTCGCGA
AAATGGCTATAAAATTGAAACGAACCACATTCCTAGAATTCCATATCTAGAAATTGTGAATAAACTTTGTGAGGTACAGT
AA

Upstream 100 bases:

>100_bases
ATGATGAGCAGTGAATTCATAAATATTTTCCCCTTGTAAAATTTATGTTATAATAGACATTATATAACTAACTGAGAATT
TTATAAAGGTAGAAGACAAA

Downstream 100 bases:

>100_bases
AATTTCTACTAAATCTAAGAAAAATAAACAAAATAAACGGGCAAAACGCGGTTCTGCTAAATCAAAATGGTGGACAGCTG
TTAAATTATTTTTGATTGTC

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MVNYPNGRSQSYSAVPKKQKTLTGLSVAKKGAPKSKSLVAFGKRGMNFEAEINATNDYYLSRGLAVIHKKPTPIQIVKVD
YPQRSRAKITEAYFRQASTTDYSGVYKGHYVDFEAKETHQKTVFPLKNFHEHQIVHMSNVLAQRGIAFILLHFAALDETY
LLPSSYLITFYYEKNGLKSIPLAYIRENGYKIETNHIPRIPYLEIVNKLCEVQ

Sequences:

>Translated_213_residues
MVNYPNGRSQSYSAVPKKQKTLTGLSVAKKGAPKSKSLVAFGKRGMNFEAEINATNDYYLSRGLAVIHKKPTPIQIVKVD
YPQRSRAKITEAYFRQASTTDYSGVYKGHYVDFEAKETHQKTVFPLKNFHEHQIVHMSNVLAQRGIAFILLHFAALDETY
LLPSSYLITFYYEKNGLKSIPLAYIRENGYKIETNHIPRIPYLEIVNKLCEVQ
>Mature_213_residues
MVNYPNGRSQSYSAVPKKQKTLTGLSVAKKGAPKSKSLVAFGKRGMNFEAEINATNDYYLSRGLAVIHKKPTPIQIVKVD
YPQRSRAKITEAYFRQASTTDYSGVYKGHYVDFEAKETHQKTVFPLKNFHEHQIVHMSNVLAQRGIAFILLHFAALDETY
LLPSSYLITFYYEKNGLKSIPLAYIRENGYKIETNHIPRIPYLEIVNKLCEVQ

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECU_LACLM (A2RIM1)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001031862.1
- ProteinModelPortal:   A2RIM1
- SMR:   A2RIM1
- STRING:   A2RIM1
- GeneID:   4796592
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_0512
- eggNOG:   COG3331
- HOGENOM:   HBG571967
- OMA:   GHYIDFE
- ProtClustDB:   PRK02234
- GO:   GO:0005737
- HAMAP:   MF_00130
- InterPro:   IPR004612
- InterPro:   IPR011335
- PIRSF:   PIRSF037785
- TIGRFAMs:   TIGR00648

Pfam domain/function: PF03838 RecU; SSF52980 Restrict_endonuc_II-like_core

EC number: NA

Molecular weight: Translated: 24324; Mature: 24324

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNYPNGRSQSYSAVPKKQKTLTGLSVAKKGAPKSKSLVAFGKRGMNFEAEINATNDYYL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEECCCCEEH
SRGLAVIHKKPTPIQIVKVDYPQRSRAKITEAYFRQASTTDYSGVYKGHYVDFEAKETHQ
HCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCC
KTVFPLKNFHEHQIVHMSNVLAQRGIAFILLHFAALDETYLLPSSYLITFYYEKNGLKSI
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCC
PLAYIRENGYKIETNHIPRIPYLEIVNKLCEVQ
CEEEEECCCEEEECCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MVNYPNGRSQSYSAVPKKQKTLTGLSVAKKGAPKSKSLVAFGKRGMNFEAEINATNDYYL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEECCCCEEH
SRGLAVIHKKPTPIQIVKVDYPQRSRAKITEAYFRQASTTDYSGVYKGHYVDFEAKETHQ
HCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCC
KTVFPLKNFHEHQIVHMSNVLAQRGIAFILLHFAALDETYLLPSSYLITFYYEKNGLKSI
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCC
PLAYIRENGYKIETNHIPRIPYLEIVNKLCEVQ
CEEEEECCCEEEECCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA