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The map label for this gene is lytR [H]

Identifier: 125623328

GI number: 125623328

Start: 455181

End: 456560

Strand: Direct

Name: lytR [H]

Synonym: llmg_0461

Alternate gene names: 125623328

Gene position: 455181-456560 (Clockwise)

Preceding gene: 125623327

Following gene: 125623329

Centisome position: 18.0

GC content: 38.91

Gene sequence:

>1380_bases
ATGAAGCTTTGGATAAAAACACTTCTCATGCTAGGAAGTATCATTTTAGTAACGGCAATTGCTGCGGGCGGATATACATT
AACCGTCTTAAACAGTACAACAAAAGCCTTTAAAATGACTTACACGAATGCTGGGAATAAACAAACAGAACAAGTCATTC
AGGCGACTAAACCTCTGACCATCCTACTTATGGGAGTCGATACAGGAGGCGAAGGTCGTGGGACTTCCGATTCTTGGAAT
GGGAATTCTGACTCACAGATTCTGATGACACTTAATCCTAAAACGCACACGACAACAATGGTTTCAATTGAACGTGATAC
AATGACTAATATTTTGGATGGTGACGGAAACATCGTCTCTAAACAAAAAATGAATGCCGCTTATCCCCTAGGTTATAACT
CAGGGACATCTTCTGATGGTTTGAAAAATGCTGTCAGTTATGCCATGAAGACAATTGGAGCTCAAACGGGTATTAATATT
GACAGCTTTGCAACTGTAAATTTTGATGGTTTAGTTAATATGGTTGATAATGTAGGTGGGATTGATATTAACAATACTAC
GGGGCAAACCTTATACATCTCAGATACAGAGCCGCAATACACTGCGAAAGTTCCACCAGGAAAACAACACATTAATGGGG
ATCAAGCTTTAGTTTATACTCGAGACCGTCATCATTTGCCAAATGGAGACTACGGTCGGGCTGCTCATCAGCGCGAAGTT
ATCGCCGCTCTCATGAAAAAAGTCTTGGCTTTGGATAATATTACTCGCTATGAGCAATTTTTGAATGAAGCCTCAAAAGA
TTTTAGAACCAATATTCCAATTAATGCCTCAACGATTACTTCTTTGTTGGGCTACAAGGATTGCTTTAATAAAGTAGTTT
CTGTTCAATATGAAGGTGTAGGCGAAATGGTTGATGGGGGTTCCTATCAATTTATGCCGACAGATATCTACCTTGCAATG
CAAAATATCATGAAGAAATCACTTGATGAATCAACTGTAACGACTTTACCAAGTAGCTTGATTACTTATGAATCGGTATT
TGGTTCAGGTACCACACCATTTTTCTATCTGCCTTCAGCTACTGTGACTGAGAAAGGAAAGACAACAGAAACTTACGGAG
TAGATACTCAAGGAAATCTTGTTTCTTTGAATTCTAAAAACTCAGGAAATTATGTTTCGAAAAGTGGTGGTTCAGTTCAA
TCGGACTCAAGTTCTGGCTCCGCTAGCTCATCAAGTGATTCTACAGTAACATCAAGTTCTGATTCGACCTATCAGCAAAA
TGATACTTACAATGATGGCTATAATAATAGTAATAATACGACTACTTATGGTAATGGAACAGATGATACCACTGCTGGAG
GATACGGCACAGGTCAATAA

Upstream 100 bases:

>100_bases
TGACCTTTTTGTTAGTAAAACTAAATATAATTAAAGAAAAATTAAAATCTAATTTTTCTTTTTTTGTTGTGAAAAATCAG
AATTTTGATATAATGCTAAT

Downstream 100 bases:

>100_bases
TTGAAAAAAGTAAGAGAATATGATAAACTTGTTTCTGTCAGTGATTTATAACTTAATAAATTTACTGACAGAAATTAATT
GGTCCGATAGCTCAGCTGGC

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKLWIKTLLMLGSIILVTAIAAGGYTLTVLNSTTKAFKMTYTNAGNKQTEQVIQATKPLTILLMGVDTGGEGRGTSDSWN
GNSDSQILMTLNPKTHTTTMVSIERDTMTNILDGDGNIVSKQKMNAAYPLGYNSGTSSDGLKNAVSYAMKTIGAQTGINI
DSFATVNFDGLVNMVDNVGGIDINNTTGQTLYISDTEPQYTAKVPPGKQHINGDQALVYTRDRHHLPNGDYGRAAHQREV
IAALMKKVLALDNITRYEQFLNEASKDFRTNIPINASTITSLLGYKDCFNKVVSVQYEGVGEMVDGGSYQFMPTDIYLAM
QNIMKKSLDESTVTTLPSSLITYESVFGSGTTPFFYLPSATVTEKGKTTETYGVDTQGNLVSLNSKNSGNYVSKSGGSVQ
SDSSSGSASSSSDSTVTSSSDSTYQQNDTYNDGYNNSNNTTTYGNGTDDTTAGGYGTGQ

Sequences:

>Translated_459_residues
MKLWIKTLLMLGSIILVTAIAAGGYTLTVLNSTTKAFKMTYTNAGNKQTEQVIQATKPLTILLMGVDTGGEGRGTSDSWN
GNSDSQILMTLNPKTHTTTMVSIERDTMTNILDGDGNIVSKQKMNAAYPLGYNSGTSSDGLKNAVSYAMKTIGAQTGINI
DSFATVNFDGLVNMVDNVGGIDINNTTGQTLYISDTEPQYTAKVPPGKQHINGDQALVYTRDRHHLPNGDYGRAAHQREV
IAALMKKVLALDNITRYEQFLNEASKDFRTNIPINASTITSLLGYKDCFNKVVSVQYEGVGEMVDGGSYQFMPTDIYLAM
QNIMKKSLDESTVTTLPSSLITYESVFGSGTTPFFYLPSATVTEKGKTTETYGVDTQGNLVSLNSKNSGNYVSKSGGSVQ
SDSSSGSASSSSDSTVTSSSDSTYQQNDTYNDGYNNSNNTTTYGNGTDDTTAGGYGTGQ
>Mature_459_residues
MKLWIKTLLMLGSIILVTAIAAGGYTLTVLNSTTKAFKMTYTNAGNKQTEQVIQATKPLTILLMGVDTGGEGRGTSDSWN
GNSDSQILMTLNPKTHTTTMVSIERDTMTNILDGDGNIVSKQKMNAAYPLGYNSGTSSDGLKNAVSYAMKTIGAQTGINI
DSFATVNFDGLVNMVDNVGGIDINNTTGQTLYISDTEPQYTAKVPPGKQHINGDQALVYTRDRHHLPNGDYGRAAHQREV
IAALMKKVLALDNITRYEQFLNEASKDFRTNIPINASTITSLLGYKDCFNKVVSVQYEGVGEMVDGGSYQFMPTDIYLAM
QNIMKKSLDESTVTTLPSSLITYESVFGSGTTPFFYLPSATVTEKGKTTETYGVDTQGNLVSLNSKNSGNYVSKSGGSVQ
SDSSSGSASSSSDSTVTSSSDSTYQQNDTYNDGYNNSNNTTTYGNGTDDTTAGGYGTGQ

Specific function: Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell envelope (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 49134; Mature: 49134

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLWIKTLLMLGSIILVTAIAAGGYTLTVLNSTTKAFKMTYTNAGNKQTEQVIQATKPLT
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEEECCCCHHHHHHHHHCCCEE
ILLMGVDTGGEGRGTSDSWNGNSDSQILMTLNPKTHTTTMVSIERDTMTNILDGDGNIVS
EEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECHHHHHEECCCCCEEE
KQKMNAAYPLGYNSGTSSDGLKNAVSYAMKTIGAQTGINIDSFATVNFDGLVNMVDNVGG
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCC
IDINNTTGQTLYISDTEPQYTAKVPPGKQHINGDQALVYTRDRHHLPNGDYGRAAHQREV
EEECCCCCCEEEEECCCCCEEEECCCCHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
IAALMKKVLALDNITRYEQFLNEASKDFRTNIPINASTITSLLGYKDCFNKVVSVQYEGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCC
GEMVDGGSYQFMPTDIYLAMQNIMKKSLDESTVTTLPSSLITYESVFGSGTTPFFYLPSA
CCCCCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCCCEEECCCC
TVTEKGKTTETYGVDTQGNLVSLNSKNSGNYVSKSGGSVQSDSSSGSASSSSDSTVTSSS
CCCCCCCCCEEECCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCC
DSTYQQNDTYNDGYNNSNNTTTYGNGTDDTTAGGYGTGQ
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLWIKTLLMLGSIILVTAIAAGGYTLTVLNSTTKAFKMTYTNAGNKQTEQVIQATKPLT
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEEECCCCHHHHHHHHHCCCEE
ILLMGVDTGGEGRGTSDSWNGNSDSQILMTLNPKTHTTTMVSIERDTMTNILDGDGNIVS
EEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECHHHHHEECCCCCEEE
KQKMNAAYPLGYNSGTSSDGLKNAVSYAMKTIGAQTGINIDSFATVNFDGLVNMVDNVGG
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCC
IDINNTTGQTLYISDTEPQYTAKVPPGKQHINGDQALVYTRDRHHLPNGDYGRAAHQREV
EEECCCCCCEEEEECCCCCEEEECCCCHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
IAALMKKVLALDNITRYEQFLNEASKDFRTNIPINASTITSLLGYKDCFNKVVSVQYEGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCC
GEMVDGGSYQFMPTDIYLAMQNIMKKSLDESTVTTLPSSLITYESVFGSGTTPFFYLPSA
CCCCCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCCCEEECCCC
TVTEKGKTTETYGVDTQGNLVSLNSKNSGNYVSKSGGSVQSDSSSGSASSSSDSTVTSSS
CCCCCCCCCEEECCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCC
DSTYQQNDTYNDGYNNSNNTTTYGNGTDDTTAGGYGTGQ
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]