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The map label for this gene is fhuG [H]

Identifier: 125623218

GI number: 125623218

Start: 335273

End: 336211

Strand: Direct

Name: fhuG [H]

Synonym: llmg_0348

Alternate gene names: 125623218

Gene position: 335273-336211 (Clockwise)

Preceding gene: 125623217

Following gene: 125623219

Centisome position: 13.25

GC content: 36.0

Gene sequence:

>939_bases
ATGAAAAGAAAATTCACTTTACTTTTTGTCCTTCTTTTGGTTTTGATTGTGGCTGATTTGACACAATTTTCGACTAATTC
TCAAATCCTATCTATTTTGATTCCTAATTTCCGTTTACCAAGATTAATAACTATTTTGTCAGCAGGGATTGCCCTTTCAT
TATCCGGTTATATCATTCAAAATATCACAGAGAACCCTCTTGCTGATAGTGGAGCAATTGGGATAACTTCTGGTGCATCA
GCAGGAAGCGTCGCCTTTTTATTAATTGCTGATCATTTTAAATTGACGGGCATTTGGAATTTTTCTTATCCCCTATTCGC
CTTAATTGGTGCCCTTCTTTCTTTTGCTTTAATTTATATTTTTGCTCTGAGAAAGCAAGTGAGCTCTGTCAGAGTACTCT
TGACAGGGATTGCAATTACAGCTTTTTTCCAAGCCCTGATTACGATTGGTCAACTTTCTGTCAATGCTTTTGATTTTCAG
AAAGTGGCAGTTTGGCTGTCAGGAGATATTTGGCAAACGGGAACCACTTATCTGATAATTTGTATTTTATTATTAGTCAT
CGGATTGATAATTCTCCCTTTTTTCCTCAAAAAACTTGAAATTTTATCCTTGGGAGAAGAAATGGCGACGGTTTTGGGAC
TTGATGTTCCCAAAACTAAAATCTATCTATACTTGCTGGCTTTACTTTTTGCAGCTGTTGGTGTTTTATTGGTTGGTGGA
TTAGCCTTTGTTGGTTTGATTGCTCCGCACATTGCAAGTGAAATTGTTGGATTTAAATCACGGAAAAGCCTAATCGCAAC
AGCTCTTTCAGGGATGATTATATTATCTTTTGCTGATATTATCTCCCAAATGATTATAGCTCCATCAAGTTTACCTTTGG
GCTTTGTTGTCGCCTTTATTGGGGCTCCATATTATATTTATCTTATACAAAAAGTTTAA

Upstream 100 bases:

>100_bases
TAGGAATTTATTTAAACCATACGAATTTCCAGCAGGAAGTTTAACCATGCTTCTGGGGGCTCCTTTCTTTTTGTGGGTCA
TTACAAAGGAGGCGAAATAA

Downstream 100 bases:

>100_bases
GAAATTAATTTACTTTTGTAAATTTCTTATAAAAAAATAATGGTTCATTTCTAAAAAATGACCTAAAAATAGAGGAGATT
CTTTTGAAAAAAGTACTCAC

Product: ferrichrome ABC transporter permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKRKFTLLFVLLLVLIVADLTQFSTNSQILSILIPNFRLPRLITILSAGIALSLSGYIIQNITENPLADSGAIGITSGAS
AGSVAFLLIADHFKLTGIWNFSYPLFALIGALLSFALIYIFALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQ
KVAVWLSGDIWQTGTTYLIICILLLVIGLIILPFFLKKLEILSLGEEMATVLGLDVPKTKIYLYLLALLFAAVGVLLVGG
LAFVGLIAPHIASEIVGFKSRKSLIATALSGMIILSFADIISQMIIAPSSLPLGFVVAFIGAPYYIYLIQKV

Sequences:

>Translated_312_residues
MKRKFTLLFVLLLVLIVADLTQFSTNSQILSILIPNFRLPRLITILSAGIALSLSGYIIQNITENPLADSGAIGITSGAS
AGSVAFLLIADHFKLTGIWNFSYPLFALIGALLSFALIYIFALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQ
KVAVWLSGDIWQTGTTYLIICILLLVIGLIILPFFLKKLEILSLGEEMATVLGLDVPKTKIYLYLLALLFAAVGVLLVGG
LAFVGLIAPHIASEIVGFKSRKSLIATALSGMIILSFADIISQMIIAPSSLPLGFVVAFIGAPYYIYLIQKV
>Mature_312_residues
MKRKFTLLFVLLLVLIVADLTQFSTNSQILSILIPNFRLPRLITILSAGIALSLSGYIIQNITENPLADSGAIGITSGAS
AGSVAFLLIADHFKLTGIWNFSYPLFALIGALLSFALIYIFALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQ
KVAVWLSGDIWQTGTTYLIICILLLVIGLIILPFFLKKLEILSLGEEMATVLGLDVPKTKIYLYLLALLFAAVGVLLVGG
LAFVGLIAPHIASEIVGFKSRKSLIATALSGMIILSFADIISQMIIAPSSLPLGFVVAFIGAPYYIYLIQKV

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=293, Percent_Identity=32.4232081911263, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786347, Length=334, Percent_Identity=34.7305389221557, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1786805, Length=304, Percent_Identity=34.8684210526316, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790741, Length=289, Percent_Identity=27.681660899654, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=32.3843416370107, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1786804, Length=286, Percent_Identity=29.7202797202797, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33644; Mature: 33644

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKFTLLFVLLLVLIVADLTQFSTNSQILSILIPNFRLPRLITILSAGIALSLSGYIIQ
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NITENPLADSGAIGITSGASAGSVAFLLIADHFKLTGIWNFSYPLFALIGALLSFALIYI
CCCCCCCCCCCCEEECCCCCCCCEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHH
FALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQKVAVWLSGDIWQTGTTYLII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCCCHHHHHH
CILLLVIGLIILPFFLKKLEILSLGEEMATVLGLDVPKTKIYLYLLALLFAAVGVLLVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAFVGLIAPHIASEIVGFKSRKSLIATALSGMIILSFADIISQMIIAPSSLPLGFVVAFI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GAPYYIYLIQKV
CCCEEEEEEECC
>Mature Secondary Structure
MKRKFTLLFVLLLVLIVADLTQFSTNSQILSILIPNFRLPRLITILSAGIALSLSGYIIQ
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NITENPLADSGAIGITSGASAGSVAFLLIADHFKLTGIWNFSYPLFALIGALLSFALIYI
CCCCCCCCCCCCEEECCCCCCCCEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHH
FALRKQVSSVRVLLTGIAITAFFQALITIGQLSVNAFDFQKVAVWLSGDIWQTGTTYLII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCCCHHHHHH
CILLLVIGLIILPFFLKKLEILSLGEEMATVLGLDVPKTKIYLYLLALLFAAVGVLLVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAFVGLIAPHIASEIVGFKSRKSLIATALSGMIILSFADIISQMIIAPSSLPLGFVVAFI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GAPYYIYLIQKV
CCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]