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The map label for this gene is amiC [H]

Identifier: 125623055

GI number: 125623055

Start: 167870

End: 169369

Strand: Direct

Name: amiC [H]

Synonym: llmg_0177

Alternate gene names: 125623055

Gene position: 167870-169369 (Clockwise)

Preceding gene: 125623054

Following gene: 125623058

Centisome position: 6.64

GC content: 40.33

Gene sequence:

>1500_bases
ATGCTTGAAATTAAAGATGCAACTTATTGGGCGGAGCAATTGAAATCAAGGAATCTTTCTGCCAAAGAATTATTAGAAAT
GACAAAGCAAAAAATTGATCAGCTCAATCCACTCTACAATGCGATTGTGGCAGAGGATTTAGCGGTCGCAAAAGAAGATT
TAGCTTTGACAGGTCAAGGTTTTTTTGCAGGACTGCCATTTGCGTTGAAAATGTTGGGGCAAACGCATAAAGGATTGCCT
GATACAGCTAGCTCTCAGCTCTTTTCAGAGAATGTGGCATCTGAGGATGATAATTATGTTAAAGCGCTGATAAGGGCAGG
ATTGACGCCTTATGGGCAGACGAATTCGCCAGAGTTTGGTTTTAAAAATATTTCGGATTCAAAACTCTACGGTGATACAC
GAAATGTTTGGAATTCTGATTATTATTCGGGTGGGTCATCTGGTGGTGCGGCTTCAGCCGTGGCTTCTGGGATGTTTGCG
ATTGCTGGAGCTTCTGATGGCGGAGGGTCAATTCGGATTCCAGCCTCATTTTCAGGTTTGATTGGTCTAAAGATGACGCG
TGGACGAATGCCACAAGGGCCGGGCTCTTATCGAGGGTGGCAAGGTGCATCTATTTCAGGGGCATTAACAGTATCGGTGC
GAGATACGGCAAGATTTATTTTGGAAATGCAAACTTTGCAAGAGGCAGCGCCTTATCAGGCTCGCTTGTTAGATGAAAAA
GAACTTTTAGAAGTCTGTGAATCTACTGACAGTTTTGTCAGTAAAAAATCGTCAGTAAAATTAAAAATTGCTTATTCTTT
GCAAAGTCCGATTTCTGGAATTGAACTTTCTGATGATGCTCTAAAAGCGGTCAAAAAAGCTGTTGAATTCTTAAAAGGAC
AGGGACATGAACTTGTGGAAATTGATTTTCCATTGAATGCACGTCCTTTAATTCAATCTTATTATCAGATGAATGCAGCG
GAAACGGTGGCTATGCTTGAACCTTGGGAAAAATCAGCGGGTCGCCAATTGACAAGTCAAGATGTTGAACTTTTGACTTA
TGCCCTTTTAGAAGCTGGACGAAAAGCGCCCGTCACCACTTATATTAATGCTTTGGCTCAATGGGATCAGGCAGCCGAAA
CCTTTGCTGACAAGATTTATGCTGACTATGATTTATTTTTGACCCCAACTACGGCAAAAACAGCGCCAAAAATTGGTGAA
GAATTAATGACAGAGGAAATATTGACCAAAATGTCAGCAATCAGTCAATATGATTTTGAACAACAAATAGCAATTATTGA
GGCGGCTTTTGAGCGTTCATTGGCCTTTACACCCTATAATTTCATCAGTAATTTGACGGGACAACCAGCTCTTTCACTAC
CGATTTATGTCAATAAAGAAACAAATCTTCCATTGGGGATTCAACTCTGGGGACCTAAAAATTCTGAAATTGAATTACTA
AAAGTAGCTAAAGAATTTGAAAATGCTGATCAGTTTATTTTGCCAAAAGCTTATCAGTAA

Upstream 100 bases:

>100_bases
TTGGAACGGATATTTTTTATTATGCTTGATAAGTATGGTAAAATGTTGGCAGAATGAGTTTGTCAGCAAAGATATAAAAC
TCAGCTTTTAAAGGAGAATC

Downstream 100 bases:

>100_bases
AAATTACTGATGGCTTATTTGCTAAAAAACTGTCAGTAAAATAAAAAAACCGTCTTAGAGACGGTTTTATGCTAAATCTT
GGTTTTGTCTAAAACGTTTA

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MLEIKDATYWAEQLKSRNLSAKELLEMTKQKIDQLNPLYNAIVAEDLAVAKEDLALTGQGFFAGLPFALKMLGQTHKGLP
DTASSQLFSENVASEDDNYVKALIRAGLTPYGQTNSPEFGFKNISDSKLYGDTRNVWNSDYYSGGSSGGAASAVASGMFA
IAGASDGGGSIRIPASFSGLIGLKMTRGRMPQGPGSYRGWQGASISGALTVSVRDTARFILEMQTLQEAAPYQARLLDEK
ELLEVCESTDSFVSKKSSVKLKIAYSLQSPISGIELSDDALKAVKKAVEFLKGQGHELVEIDFPLNARPLIQSYYQMNAA
ETVAMLEPWEKSAGRQLTSQDVELLTYALLEAGRKAPVTTYINALAQWDQAAETFADKIYADYDLFLTPTTAKTAPKIGE
ELMTEEILTKMSAISQYDFEQQIAIIEAAFERSLAFTPYNFISNLTGQPALSLPIYVNKETNLPLGIQLWGPKNSEIELL
KVAKEFENADQFILPKAYQ

Sequences:

>Translated_499_residues
MLEIKDATYWAEQLKSRNLSAKELLEMTKQKIDQLNPLYNAIVAEDLAVAKEDLALTGQGFFAGLPFALKMLGQTHKGLP
DTASSQLFSENVASEDDNYVKALIRAGLTPYGQTNSPEFGFKNISDSKLYGDTRNVWNSDYYSGGSSGGAASAVASGMFA
IAGASDGGGSIRIPASFSGLIGLKMTRGRMPQGPGSYRGWQGASISGALTVSVRDTARFILEMQTLQEAAPYQARLLDEK
ELLEVCESTDSFVSKKSSVKLKIAYSLQSPISGIELSDDALKAVKKAVEFLKGQGHELVEIDFPLNARPLIQSYYQMNAA
ETVAMLEPWEKSAGRQLTSQDVELLTYALLEAGRKAPVTTYINALAQWDQAAETFADKIYADYDLFLTPTTAKTAPKIGE
ELMTEEILTKMSAISQYDFEQQIAIIEAAFERSLAFTPYNFISNLTGQPALSLPIYVNKETNLPLGIQLWGPKNSEIELL
KVAKEFENADQFILPKAYQ
>Mature_499_residues
MLEIKDATYWAEQLKSRNLSAKELLEMTKQKIDQLNPLYNAIVAEDLAVAKEDLALTGQGFFAGLPFALKMLGQTHKGLP
DTASSQLFSENVASEDDNYVKALIRAGLTPYGQTNSPEFGFKNISDSKLYGDTRNVWNSDYYSGGSSGGAASAVASGMFA
IAGASDGGGSIRIPASFSGLIGLKMTRGRMPQGPGSYRGWQGASISGALTVSVRDTARFILEMQTLQEAAPYQARLLDEK
ELLEVCESTDSFVSKKSSVKLKIAYSLQSPISGIELSDDALKAVKKAVEFLKGQGHELVEIDFPLNARPLIQSYYQMNAA
ETVAMLEPWEKSAGRQLTSQDVELLTYALLEAGRKAPVTTYINALAQWDQAAETFADKIYADYDLFLTPTTAKTAPKIGE
ELMTEEILTKMSAISQYDFEQQIAIIEAAFERSLAFTPYNFISNLTGQPALSLPIYVNKETNLPLGIQLWGPKNSEIELL
KVAKEFENADQFILPKAYQ

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=197, Percent_Identity=30.4568527918782, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17556264, Length=144, Percent_Identity=36.1111111111111, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538252, Length=152, Percent_Identity=32.8947368421053, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71990152, Length=265, Percent_Identity=30.188679245283, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537465, Length=209, Percent_Identity=29.1866028708134, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550774, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648435, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648437, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24652985, Length=201, Percent_Identity=32.3383084577114, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922090, Length=201, Percent_Identity=32.3383084577114, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652981, Length=201, Percent_Identity=32.3383084577114, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24652983, Length=201, Percent_Identity=32.3383084577114, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644968, Length=202, Percent_Identity=29.2079207920792, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24648113, Length=455, Percent_Identity=26.8131868131868, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 54592; Mature: 54592

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIKDATYWAEQLKSRNLSAKELLEMTKQKIDQLNPLYNAIVAEDLAVAKEDLALTGQG
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
FFAGLPFALKMLGQTHKGLPDTASSQLFSENVASEDDNYVKALIRAGLTPYGQTNSPEFG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
FKNISDSKLYGDTRNVWNSDYYSGGSSGGAASAVASGMFAIAGASDGGGSIRIPASFSGL
CCCCCCCHHCCCHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCEEEECCCCCCC
IGLKMTRGRMPQGPGSYRGWQGASISGALTVSVRDTARFILEMQTLQEAAPYQARLLDEK
EEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHHHCCHH
ELLEVCESTDSFVSKKSSVKLKIAYSLQSPISGIELSDDALKAVKKAVEFLKGQGHELVE
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHCCCCEEEE
IDFPLNARPLIQSYYQMNAAETVAMLEPWEKSAGRQLTSQDVELLTYALLEAGRKAPVTT
EECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHH
YINALAQWDQAAETFADKIYADYDLFLTPTTAKTAPKIGEELMTEEILTKMSAISQYDFE
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QQIAIIEAAFERSLAFTPYNFISNLTGQPALSLPIYVNKETNLPLGIQLWGPKNSEIELL
HHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEECCEEEECCCCCCEEEEEECCCCCCHHHH
KVAKEFENADQFILPKAYQ
HHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLEIKDATYWAEQLKSRNLSAKELLEMTKQKIDQLNPLYNAIVAEDLAVAKEDLALTGQG
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
FFAGLPFALKMLGQTHKGLPDTASSQLFSENVASEDDNYVKALIRAGLTPYGQTNSPEFG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
FKNISDSKLYGDTRNVWNSDYYSGGSSGGAASAVASGMFAIAGASDGGGSIRIPASFSGL
CCCCCCCHHCCCHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCEEEECCCCCCC
IGLKMTRGRMPQGPGSYRGWQGASISGALTVSVRDTARFILEMQTLQEAAPYQARLLDEK
EEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHHHCCHH
ELLEVCESTDSFVSKKSSVKLKIAYSLQSPISGIELSDDALKAVKKAVEFLKGQGHELVE
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHCCCCEEEE
IDFPLNARPLIQSYYQMNAAETVAMLEPWEKSAGRQLTSQDVELLTYALLEAGRKAPVTT
EECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHH
YINALAQWDQAAETFADKIYADYDLFLTPTTAKTAPKIGEELMTEEILTKMSAISQYDFE
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QQIAIIEAAFERSLAFTPYNFISNLTGQPALSLPIYVNKETNLPLGIQLWGPKNSEIELL
HHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEECCEEEECCCCCCEEEEEECCCCCCHHHH
KVAKEFENADQFILPKAYQ
HHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]