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The map label for this gene is aroC [H]

Identifier: 124486461

GI number: 124486461

Start: 1676925

End: 1677998

Strand: Reverse

Name: aroC [H]

Synonym: Mlab_1649

Alternate gene names: 124486461

Gene position: 1677998-1676925 (Counterclockwise)

Preceding gene: 124486462

Following gene: 124486460

Centisome position: 92.97

GC content: 56.05

Gene sequence:

>1074_bases
ATGAATCGAATCGGAGAATCAATAACGCTCACGTTGTTTGGGGCGAGTCACGACAGTCGTATCGGCTGTGTTATAGACGG
AATTCCTCCGGGCTATCCTGTAAACGTTGAGAGTATCACTGCAGATCTCGAGCTTAGAAAACCATCCGCCGGTATCGGAA
CTCCGCGGGTGGAGGCGGATGTTCCTGAGATCTCCGGTATTGTGGATGGAATCACTACGGGCTGTCCGGTCGTGATTACT
TTTTCAAACAGCAATACCCGGAGTTCGGATTATGAACAACTCCGCCGCATCCCCCGTCCGGGCCATGCCGATTACCCTGC
GGTATCAAAATTCGGTCCGGCTCATGACATCCGTGGCGGCGGGATGTTTTCCGGCAGAATGACGACTCCCCTTGTTGCGG
CTGGTGCTCTCCTCCGTGATCTGATCGGCAGTTTGGGAATCTCCGTCGGCTCGTATGTTACCCGGATCGGCAGCGTCGTC
GATACAAATACCTACGATCCTGCCGATGTGCTGACGAGATCGCGGACAAATCCGCTTCGTGCCATGTCTTCGGGCATCGA
GGATCGGATGAGAGCCGAGATCCTCGTGGCGAAATCGGATGGAGACAGTGTCGGCGGGATCGTTCGGTGCTTTGCGACAG
GTCTTCCGGCTGGTCTTGGAGAGCCTTTCTTCGACACGCTCGACGGCGAGATATCTAAAGCGGTTTTCGCCATTCCCGGC
GTGAAAGCCATCGGATTTGGCGAGGGGTTCGCCGCCGCTGGCCTTCGCGGATCCGAAAACAACGATGCCTACCGTATTCA
AAATGGGTCTGTCGTCACGCTGACGAATCATGCGGGCGGCGTCCTTGGCGGGATGTCGAGCGGCGCTGTTCTGGATTTTT
CCGTGGCATTCAAGCCGACCCCGTCTATTGCAAAACAGCAGATGAGTGTTGATCTGCTGACCCGCGAAGACGCCGAACTT
TCAGTGAAAGGACGCCACGATCCGTGCATTGCGAATCGGGGAGCGATCGTAGTCGAAGCGATGACCGTGTTCACGCTTGC
GGATCTCGCACTCAGAGGGGGATTTCTTGTCTGA

Upstream 100 bases:

>100_bases
CAGATAGTACTACGACCGTAGATGATGCCGGCTGCTGCGCAGTTTCCTATCCGGGTTTTGTGAAAGATATGCAGAAACTC
GGTGCGGATATGAGGGAAGA

Downstream 100 bases:

>100_bases
TATTAATGGATTCAGGGATGAACTGGCGTCGATCGACCGCGAGATCATGGAACTTGTCGGCCGCAGAAACAAAATAGCTC
TGGAGATCGGTGAGAAAAAG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MNRIGESITLTLFGASHDSRIGCVIDGIPPGYPVNVESITADLELRKPSAGIGTPRVEADVPEISGIVDGITTGCPVVIT
FSNSNTRSSDYEQLRRIPRPGHADYPAVSKFGPAHDIRGGGMFSGRMTTPLVAAGALLRDLIGSLGISVGSYVTRIGSVV
DTNTYDPADVLTRSRTNPLRAMSSGIEDRMRAEILVAKSDGDSVGGIVRCFATGLPAGLGEPFFDTLDGEISKAVFAIPG
VKAIGFGEGFAAAGLRGSENNDAYRIQNGSVVTLTNHAGGVLGGMSSGAVLDFSVAFKPTPSIAKQQMSVDLLTREDAEL
SVKGRHDPCIANRGAIVVEAMTVFTLADLALRGGFLV

Sequences:

>Translated_357_residues
MNRIGESITLTLFGASHDSRIGCVIDGIPPGYPVNVESITADLELRKPSAGIGTPRVEADVPEISGIVDGITTGCPVVIT
FSNSNTRSSDYEQLRRIPRPGHADYPAVSKFGPAHDIRGGGMFSGRMTTPLVAAGALLRDLIGSLGISVGSYVTRIGSVV
DTNTYDPADVLTRSRTNPLRAMSSGIEDRMRAEILVAKSDGDSVGGIVRCFATGLPAGLGEPFFDTLDGEISKAVFAIPG
VKAIGFGEGFAAAGLRGSENNDAYRIQNGSVVTLTNHAGGVLGGMSSGAVLDFSVAFKPTPSIAKQQMSVDLLTREDAEL
SVKGRHDPCIANRGAIVVEAMTVFTLADLALRGGFLV
>Mature_357_residues
MNRIGESITLTLFGASHDSRIGCVIDGIPPGYPVNVESITADLELRKPSAGIGTPRVEADVPEISGIVDGITTGCPVVIT
FSNSNTRSSDYEQLRRIPRPGHADYPAVSKFGPAHDIRGGGMFSGRMTTPLVAAGALLRDLIGSLGISVGSYVTRIGSVV
DTNTYDPADVLTRSRTNPLRAMSSGIEDRMRAEILVAKSDGDSVGGIVRCFATGLPAGLGEPFFDTLDGEISKAVFAIPG
VKAIGFGEGFAAAGLRGSENNDAYRIQNGSVVTLTNHAGGVLGGMSSGAVLDFSVAFKPTPSIAKQQMSVDLLTREDAEL
SVKGRHDPCIANRGAIVVEAMTVFTLADLALRGGFLV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=356, Percent_Identity=38.2022471910112, Blast_Score=205, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6321290, Length=365, Percent_Identity=34.7945205479452, Blast_Score=216, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 37195; Mature: 37195

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIGESITLTLFGASHDSRIGCVIDGIPPGYPVNVESITADLELRKPSAGIGTPRVEAD
CCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHEEEEEEEECCCCCCCCCCCCCC
VPEISGIVDGITTGCPVVITFSNSNTRSSDYEQLRRIPRPGHADYPAVSKFGPAHDIRGG
CHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCC
GMFSGRMTTPLVAAGALLRDLIGSLGISVGSYVTRIGSVVDTNTYDPADVLTRSRTNPLR
CEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHH
AMSSGIEDRMRAEILVAKSDGDSVGGIVRCFATGLPAGLGEPFFDTLDGEISKAVFAIPG
HHHHCHHHHCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHEEEECCC
VKAIGFGEGFAAAGLRGSENNDAYRIQNGSVVTLTNHAGGVLGGMSSGAVLDFSVAFKPT
CEEEECCCCHHHCCCCCCCCCCEEEEECCCEEEEECCCCCEECCCCCCCEEEEEEEECCC
PSIAKQQMSVDLLTREDAELSVKGRHDPCIANRGAIVVEAMTVFTLADLALRGGFLV
HHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNRIGESITLTLFGASHDSRIGCVIDGIPPGYPVNVESITADLELRKPSAGIGTPRVEAD
CCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHEEEEEEEECCCCCCCCCCCCCC
VPEISGIVDGITTGCPVVITFSNSNTRSSDYEQLRRIPRPGHADYPAVSKFGPAHDIRGG
CHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCC
GMFSGRMTTPLVAAGALLRDLIGSLGISVGSYVTRIGSVVDTNTYDPADVLTRSRTNPLR
CEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHH
AMSSGIEDRMRAEILVAKSDGDSVGGIVRCFATGLPAGLGEPFFDTLDGEISKAVFAIPG
HHHHCHHHHCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHEEEECCC
VKAIGFGEGFAAAGLRGSENNDAYRIQNGSVVTLTNHAGGVLGGMSSGAVLDFSVAFKPT
CEEEECCCCHHHCCCCCCCCCCEEEEECCCEEEEECCCCCEECCCCCCCEEEEEEEECCC
PSIAKQQMSVDLLTREDAELSVKGRHDPCIANRGAIVVEAMTVFTLADLALRGGFLV
HHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11121031 [H]