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The map label for this gene is fdhC [H]

Identifier: 124486319

GI number: 124486319

Start: 1537965

End: 1538720

Strand: Reverse

Name: fdhC [H]

Synonym: Mlab_1504

Alternate gene names: 124486319

Gene position: 1538720-1537965 (Counterclockwise)

Preceding gene: 124486322

Following gene: 124486318

Centisome position: 85.25

GC content: 48.94

Gene sequence:

>756_bases
ATGGTTACATTCAGTCCAGCGCAGGTATGCGTGAAAATTGGAACCGCTGGCAAATCCAAGGCCAGTCTTCCTGCATTAAA
TATGCTTGTACGTGCATTTCTTGCGGGCGCCTATGTTGCAATGGGTGCTACGCTTGCAACAGTCAGTTCCACTGACGTAA
CGGCCTATTTCGGGCCGGGTATTGCTCAATTTGTTGTTGGTGCTGTATTCCCGGTCGGGTTGATGCTCGTCGTCTTTACC
GGGGCTGAGCTTTTTACCGGCGATGCGATGTTTGCTCCGATGTCGATTCTTCAGGGATATATCGGCATTCGAAAGCTCAT
CTATCTGTGGAGCATCGTCTACATTGGCAATCTTATTGGGTCTGTATTCATGGCATTTCTTGTCAGTTACGGTCCCTACA
CTTCATGGGATTCTGCCGGTGTTGTGACGGTAACGGCGTTTGGCCTTCGTGCGATCCAGATAGGTTCCGCCAAAGTTGCC
TACACCGGGACGATGGGTTTGTTTTCCTGTTTCCTGAAAGGTATCCTTTGTAACTGGCTTGTCTGTCTTGCTCTGTTTCT
GGGGCTTGCCGCTGATGATGTGATATCGAAGATAGCCGCTCTTTGGTTTCCGATTATGGCGTTTGCTGCTTCGGGATTCG
AGCACTGTATCGCAAACATGTTCTTCATCCCGGCCGCCATCATTACCAATGGCTTTACCGGAAATATTGTTGTGAATTTG
AACTGGGTGGGTATGTGGACAAACAACATCATCTAG

Upstream 100 bases:

>100_bases
TTAATCATGTTAAAAAGAATGATTGATATACTGGTTCCTGCCTAATGAGTATGATCACATCACATTGGGTTTTTCGACTG
AATTGTGAAGGGGTAGAATT

Downstream 100 bases:

>100_bases
GTTACTCTTGGTAATATCGTAGGTGCAGTAATTTTCATGGCGATCGCCTATTATTATTGTTACAAAATGGAGATATGTGC
GTTGTGCGAAACTGCGTAAG

Product: hypothetical protein

Products: Proton [Cytoplasm]; nitrite [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MVTFSPAQVCVKIGTAGKSKASLPALNMLVRAFLAGAYVAMGATLATVSSTDVTAYFGPGIAQFVVGAVFPVGLMLVVFT
GAELFTGDAMFAPMSILQGYIGIRKLIYLWSIVYIGNLIGSVFMAFLVSYGPYTSWDSAGVVTVTAFGLRAIQIGSAKVA
YTGTMGLFSCFLKGILCNWLVCLALFLGLAADDVISKIAALWFPIMAFAASGFEHCIANMFFIPAAIITNGFTGNIVVNL
NWVGMWTNNII

Sequences:

>Translated_251_residues
MVTFSPAQVCVKIGTAGKSKASLPALNMLVRAFLAGAYVAMGATLATVSSTDVTAYFGPGIAQFVVGAVFPVGLMLVVFT
GAELFTGDAMFAPMSILQGYIGIRKLIYLWSIVYIGNLIGSVFMAFLVSYGPYTSWDSAGVVTVTAFGLRAIQIGSAKVA
YTGTMGLFSCFLKGILCNWLVCLALFLGLAADDVISKIAALWFPIMAFAASGFEHCIANMFFIPAAIITNGFTGNIVVNL
NWVGMWTNNII
>Mature_251_residues
MVTFSPAQVCVKIGTAGKSKASLPALNMLVRAFLAGAYVAMGATLATVSSTDVTAYFGPGIAQFVVGAVFPVGLMLVVFT
GAELFTGDAMFAPMSILQGYIGIRKLIYLWSIVYIGNLIGSVFMAFLVSYGPYTSWDSAGVVTVTAFGLRAIQIGSAKVA
YTGTMGLFSCFLKGILCNWLVCLALFLGLAADDVISKIAALWFPIMAFAASGFEHCIANMFFIPAAIITNGFTGNIVVNL
NWVGMWTNNII

Specific function: May act as a formate transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI87082249, Length=203, Percent_Identity=34.9753694581281, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787132, Length=228, Percent_Identity=32.0175438596491, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788837, Length=215, Percent_Identity=31.1627906976744, Blast_Score=81, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6321779, Length=220, Percent_Identity=29.0909090909091, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 26547; Mature: 26547

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTFSPAQVCVKIGTAGKSKASLPALNMLVRAFLAGAYVAMGATLATVSSTDVTAYFGPG
CCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCC
IAQFVVGAVFPVGLMLVVFTGAELFTGDAMFAPMSILQGYIGIRKLIYLWSIVYIGNLIG
HHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVFMAFLVSYGPYTSWDSAGVVTVTAFGLRAIQIGSAKVAYTGTMGLFSCFLKGILCNWL
HHHHHHHHHCCCCCCCCCCCEEEEEEHHHHEEEECCCEEEEECHHHHHHHHHHHHHHHHH
VCLALFLGLAADDVISKIAALWFPIMAFAASGFEHCIANMFFIPAAIITNGFTGNIVVNL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
NWVGMWTNNII
EEEEECCCCCC
>Mature Secondary Structure
MVTFSPAQVCVKIGTAGKSKASLPALNMLVRAFLAGAYVAMGATLATVSSTDVTAYFGPG
CCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCC
IAQFVVGAVFPVGLMLVVFTGAELFTGDAMFAPMSILQGYIGIRKLIYLWSIVYIGNLIG
HHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVFMAFLVSYGPYTSWDSAGVVTVTAFGLRAIQIGSAKVAYTGTMGLFSCFLKGILCNWL
HHHHHHHHHCCCCCCCCCCCEEEEEEHHHHEEEECCCEEEEECHHHHHHHHHHHHHHHHH
VCLALFLGLAADDVISKIAALWFPIMAFAASGFEHCIANMFFIPAAIITNGFTGNIVVNL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
NWVGMWTNNII
EEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; nitrite [Periplasm] [C]

Specific reaction: Proton [Periplasm] + nitrite [Periplasm] = Proton [Cytoplasm] + nitrite [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1378430 [H]