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The map label for this gene is fdhC [H]

Identifier: 124486318

GI number: 124486318

Start: 1536417

End: 1537271

Strand: Reverse

Name: fdhC [H]

Synonym: Mlab_1503

Alternate gene names: 124486318

Gene position: 1537271-1536417 (Counterclockwise)

Preceding gene: 124486319

Following gene: 124486317

Centisome position: 85.17

GC content: 49.36

Gene sequence:

>855_bases
ATGGTCACATTCAGTCCGGCGCAGGTATGCGTCAAAATTGGAGCGGCCGGCAAAACAAAATGCAACCTTCCGGCATTTAA
CATGCTGGTTCGTGCATTCCTTGCTGGTGCATATATTGCAATGGGTGCTGCCCTTGCAACAGTTGGATCAACCGGAGTCT
CCGCAGTATTCGGTGCAGGTATCAGCCAGTTTGTTACTGGTGCACTTTTCCCGATCGGTTTAATTATCATCGTTTTAACC
GGTGCAGAACTCTTTACCGGCGACGCAATGTTTGCCCCAATGGCAGTCCTTCAGGGTCATGTCGGCATTGGCAGACTCGT
CTATCTCTGGGTTGTTGTTTATATCGGTAACCTTATTGGATCTATCTTCATGGCATTCATGGCCAGCTACGGCCCATACA
CGTCCTGGAGCGCAGCAGGTGTTGCAACCGTAACCGCCTTTGGTCTTTGTGCAATCGCAATCGGAACCGCAAAAGTCTCC
TATACTGGAGCAATGGGCATTCTCTCCTGCTTCCTGAAAGCTATCCTTTGTAACTGGCTCGTCTGTCTGGCACTCTTCCT
CGGCCTCGCAGCAGATGATGTAATCGGCAAGATTGTTGCAATCTGGTTCCCGATCATGGCTTTCGTTGCCTCCGGATATG
AACACTGTGTTGCTAACATGTACTTCATCCCAGCCGCCATCATTACAAACGGCTTCACCGGAAACACTGTGGACAACCTG
AACTGGGTTGGTATGTGGACGAACAACATTATCTGGGCTACCCTTGGTAACATCGTTGGTGCCGTCATCTTCATGGCCAT
CGTCTACTACTACTGCTACAAGTCAGAAATCTGTGCACTCTGTGAAACAAAATAA

Upstream 100 bases:

>100_bases
TCTTCATGTCAATTGGTATGATTTAAATAGAAACTACTCCAATCAGAAAATAACGCAACCCGGTTAGGTATTTCCTGATC
GGATTGTGAGGTGTTTATTT

Downstream 100 bases:

>100_bases
GATAAGCCCGGCGTAGGAAATACGCCTCTTATCTAAAACCATCTCTTTCTTTTTTCTGCATTGCAAGACATGCATCTATT
TAACCTAAGAAATATCACTA

Product: hypothetical protein

Products: Proton [Cytoplasm]; nitrite [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MVTFSPAQVCVKIGAAGKTKCNLPAFNMLVRAFLAGAYIAMGAALATVGSTGVSAVFGAGISQFVTGALFPIGLIIIVLT
GAELFTGDAMFAPMAVLQGHVGIGRLVYLWVVVYIGNLIGSIFMAFMASYGPYTSWSAAGVATVTAFGLCAIAIGTAKVS
YTGAMGILSCFLKAILCNWLVCLALFLGLAADDVIGKIVAIWFPIMAFVASGYEHCVANMYFIPAAIITNGFTGNTVDNL
NWVGMWTNNIIWATLGNIVGAVIFMAIVYYYCYKSEICALCETK

Sequences:

>Translated_284_residues
MVTFSPAQVCVKIGAAGKTKCNLPAFNMLVRAFLAGAYIAMGAALATVGSTGVSAVFGAGISQFVTGALFPIGLIIIVLT
GAELFTGDAMFAPMAVLQGHVGIGRLVYLWVVVYIGNLIGSIFMAFMASYGPYTSWSAAGVATVTAFGLCAIAIGTAKVS
YTGAMGILSCFLKAILCNWLVCLALFLGLAADDVIGKIVAIWFPIMAFVASGYEHCVANMYFIPAAIITNGFTGNTVDNL
NWVGMWTNNIIWATLGNIVGAVIFMAIVYYYCYKSEICALCETK
>Mature_284_residues
MVTFSPAQVCVKIGAAGKTKCNLPAFNMLVRAFLAGAYIAMGAALATVGSTGVSAVFGAGISQFVTGALFPIGLIIIVLT
GAELFTGDAMFAPMAVLQGHVGIGRLVYLWVVVYIGNLIGSIFMAFMASYGPYTSWSAAGVATVTAFGLCAIAIGTAKVS
YTGAMGILSCFLKAILCNWLVCLALFLGLAADDVIGKIVAIWFPIMAFVASGYEHCVANMYFIPAAIITNGFTGNTVDNL
NWVGMWTNNIIWATLGNIVGAVIFMAIVYYYCYKSEICALCETK

Specific function: May act as a formate transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI87082249, Length=243, Percent_Identity=31.6872427983539, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787132, Length=282, Percent_Identity=29.4326241134752, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788837, Length=281, Percent_Identity=27.0462633451957, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321779, Length=277, Percent_Identity=29.2418772563177, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 29836; Mature: 29836

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; nitrite [Periplasm] [C]

Specific reaction: Proton [Periplasm] + nitrite [Periplasm] = Proton [Cytoplasm] + nitrite [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9006048 [H]