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The map label for this gene is ribD [C]

Identifier: 124485759

GI number: 124485759

Start: 934754

End: 935431

Strand: Reverse

Name: ribD [C]

Synonym: Mlab_0937

Alternate gene names: 124485759

Gene position: 935431-934754 (Counterclockwise)

Preceding gene: 124485761

Following gene: 124485757

Centisome position: 51.83

GC content: 54.13

Gene sequence:

>678_bases
ATGCGTCCGTATGTGATAATCAACGCAGCCATGAGCGCTGACGGGAAACTCGCCACCCGGGAAAGGAAACAGACCAAAAT
ATCCGGTCATGATGACTTTTTGCGGGTGGACCGTCTTCGTGCCGATTCGGACGCGATAATGGTGGGTATAGGAACCGTCC
TCTCCGACGATCCCTCTCTTCGCCTCAAAAGCGAGGAGCATGCCGGCATGCGAAAAGCAAACGGCAAGGATCCGCATCCG
ATGCGGGTCGTTATCGACAGCACGGCAAAAATGCCCGCTGACGGCGATATGTTCAAAAAAGGACTTGGCCGCGTGGTGAT
TTTCGTCTCTGAAAAGGCGCAAAAGGAAAAGTGCGATGCTCTGAGAGAAAAAGCGACCGTGATCTCTGCCGGCCGCGACT
CTGTCGATCTGGAAATCGTTTTGGACGAACTCTCAAAACTCGGCGTCGAAAAACTCATGGTCGAGGGGGGGTCGACCCTT
CTCTGGTCCTTTATGAGCAGCGGTCTCTTTGATGAAATACGCATATACATCGGAGCGCTGATCATCGGCGGGAAAGATGC
TCCGACCTTTGCCGACGGACAGGGCTTCACGGATCCTGACGATTTCACCCGTCTCACGCTCAAAGATATCGAGCGGATCG
ATGACGGCGTCCTGCTGACCTGGGTAAAAAAGGCGTGA

Upstream 100 bases:

>100_bases
TGTCCGCGTTGGTGTAAACGTTTATAAAAAGATCTAAGACGTTACGATCTATTCTCTTTTCAATGATCCGTCTACGTCTG
CGTGTCTGTAAGGTAACTGT

Downstream 100 bases:

>100_bases
ATATTATTTTACCAGCCGCTTTTTCCGAAGCAGCCGGTTATACGTAACAGCAAATCTGTGGGCCTCGTCCCGTATCTCCT
GAAGGTACATGTTTGCCTTC

Product: 2, 5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one reductase

Products: NA

Alternate protein names: HTP reductase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRPYVIINAAMSADGKLATRERKQTKISGHDDFLRVDRLRADSDAIMVGIGTVLSDDPSLRLKSEEHAGMRKANGKDPHP
MRVVIDSTAKMPADGDMFKKGLGRVVIFVSEKAQKEKCDALREKATVISAGRDSVDLEIVLDELSKLGVEKLMVEGGSTL
LWSFMSSGLFDEIRIYIGALIIGGKDAPTFADGQGFTDPDDFTRLTLKDIERIDDGVLLTWVKKA

Sequences:

>Translated_225_residues
MRPYVIINAAMSADGKLATRERKQTKISGHDDFLRVDRLRADSDAIMVGIGTVLSDDPSLRLKSEEHAGMRKANGKDPHP
MRVVIDSTAKMPADGDMFKKGLGRVVIFVSEKAQKEKCDALREKATVISAGRDSVDLEIVLDELSKLGVEKLMVEGGSTL
LWSFMSSGLFDEIRIYIGALIIGGKDAPTFADGQGFTDPDDFTRLTLKDIERIDDGVLLTWVKKA
>Mature_225_residues
MRPYVIINAAMSADGKLATRERKQTKISGHDDFLRVDRLRADSDAIMVGIGTVLSDDPSLRLKSEEHAGMRKANGKDPHP
MRVVIDSTAKMPADGDMFKKGLGRVVIFVSEKAQKEKCDALREKATVISAGRDSVDLEIVLDELSKLGVEKLMVEGGSTL
LWSFMSSGLFDEIRIYIGALIIGGKDAPTFADGQGFTDPDDFTRLTLKDIERIDDGVLLTWVKKA

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=225, Percent_Identity=26.2222222222222, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: =1.1.1.193 [H]

Molecular weight: Translated: 24699; Mature: 24699

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYVIINAAMSADGKLATRERKQTKISGHDDFLRVDRLRADSDAIMVGIGTVLSDDPSL
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEECHHCCCCCCE
RLKSEEHAGMRKANGKDPHPMRVVIDSTAKMPADGDMFKKGLGRVVIFVSEKAQKEKCDA
EEECHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCEEEEEECCCHHHHHHHH
LREKATVISAGRDSVDLEIVLDELSKLGVEKLMVEGGSTLLWSFMSSGLFDEIRIYIGAL
HHHHHHEEECCCCCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHEEE
IIGGKDAPTFADGQGFTDPDDFTRLTLKDIERIDDGVLLTWVKKA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MRPYVIINAAMSADGKLATRERKQTKISGHDDFLRVDRLRADSDAIMVGIGTVLSDDPSL
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEECHHCCCCCCE
RLKSEEHAGMRKANGKDPHPMRVVIDSTAKMPADGDMFKKGLGRVVIFVSEKAQKEKCDA
EEECHHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCEEEEEECCCHHHHHHHH
LREKATVISAGRDSVDLEIVLDELSKLGVEKLMVEGGSTLLWSFMSSGLFDEIRIYIGAL
HHHHHHEEECCCCCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHEEE
IIGGKDAPTFADGQGFTDPDDFTRLTLKDIERIDDGVLLTWVKKA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]