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The map label for this gene is 124485745

Identifier: 124485745

GI number: 124485745

Start: 918549

End: 919418

Strand: Reverse

Name: 124485745

Synonym: Mlab_0923

Alternate gene names: NA

Gene position: 919418-918549 (Counterclockwise)

Preceding gene: 124485746

Following gene: 124485744

Centisome position: 50.94

GC content: 57.01

Gene sequence:

>870_bases
ATGAAGATCAGGAAGATTTCGAAGCGATCGCTCCCGAATGCAGCGAGTGAACCCTGGGTTGATGCGACCCGCCGCGTCTA
CTGCGAAGGTGAGTATGCCTTCGTTCCGGTGAAGGAAGGCTATCCCTTCGACGGCGAGATCCCCGACCGACGTCCATACT
CAGGTCCCGGATATCAGCGGATGGGAGACACCCTTCTTCTGCACGGCGATGCTCCGACAGCCGACGAGCTCGCCGCTCTC
ATCGCATGGGAAAAACCCTCCTGCGTGATTCACGCCGCGACCCACGAAGGGGTCATGCGTACGCCGAAGGCTTCCGTTCT
CTTTGGTCAGCCCCACGACGTGACGTTTCGGGAAGCGGGCATCACCTACACGCTCGACCCTTCAAAGGTCATGTTTTCGC
AAGGAAACCGGGGCGAAAAACTCCGGCTCCGTTCTCTCGTAAAGCCCGGCGAGCGGATCGCCGACATGTTTGCCGGCATC
GGCTATTTTACCCTCTCGGCGGCGCTTGCCGGCGGCAATGTACATGCGGTTGAAATCAATCCGGTCTCTTTTGCCTATCT
CGAGAAAAATATCGAAGCGAACGACCTCGCGGGCAGGGTCACCCCAGAGCTCGGTGACTGCCGTGAGAGACTTTTCGGGA
TCTACGACCGGATCCTCATGGGACATTTCGAAGCTCCCGACTTTTTAAAAACCGCTTTGGATCACGCGGAGCCGGGCACC
GTTCTGCATGTTCACGGGGTCGGGGACCGGAAAAACGACATAACCGAGACTCTCGAAGGGGCAGGTTTTACGTATATTAT
CAGCGAACATAAAGTAAAGAAGTATGCGGGGCGCCTCTGGCACTCGGTTTGGGATGTGAACCTCATATGA

Upstream 100 bases:

>100_bases
ACGACCGAAGAGATCGCCGAACGTTCCTGGCTCGATACAAGGGAAGGCGACACGATCCTGTTTGTCCGTGACGGAGAAAC
GCTTGTGTTAGTTGGAAGAG

Downstream 100 bases:

>100_bases
AAAGACTCAACAATATCCGCATCGTTCTCGGCGTATGCGGCAGTATCGCCGCTGTCGAGACGATCAAACTCGCCCACGAG
CTCAGACGCCGGGGAGCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKIRKISKRSLPNAASEPWVDATRRVYCEGEYAFVPVKEGYPFDGEIPDRRPYSGPGYQRMGDTLLLHGDAPTADELAAL
IAWEKPSCVIHAATHEGVMRTPKASVLFGQPHDVTFREAGITYTLDPSKVMFSQGNRGEKLRLRSLVKPGERIADMFAGI
GYFTLSAALAGGNVHAVEINPVSFAYLEKNIEANDLAGRVTPELGDCRERLFGIYDRILMGHFEAPDFLKTALDHAEPGT
VLHVHGVGDRKNDITETLEGAGFTYIISEHKVKKYAGRLWHSVWDVNLI

Sequences:

>Translated_289_residues
MKIRKISKRSLPNAASEPWVDATRRVYCEGEYAFVPVKEGYPFDGEIPDRRPYSGPGYQRMGDTLLLHGDAPTADELAAL
IAWEKPSCVIHAATHEGVMRTPKASVLFGQPHDVTFREAGITYTLDPSKVMFSQGNRGEKLRLRSLVKPGERIADMFAGI
GYFTLSAALAGGNVHAVEINPVSFAYLEKNIEANDLAGRVTPELGDCRERLFGIYDRILMGHFEAPDFLKTALDHAEPGT
VLHVHGVGDRKNDITETLEGAGFTYIISEHKVKKYAGRLWHSVWDVNLI
>Mature_289_residues
MKIRKISKRSLPNAASEPWVDATRRVYCEGEYAFVPVKEGYPFDGEIPDRRPYSGPGYQRMGDTLLLHGDAPTADELAAL
IAWEKPSCVIHAATHEGVMRTPKASVLFGQPHDVTFREAGITYTLDPSKVMFSQGNRGEKLRLRSLVKPGERIADMFAGI
GYFTLSAALAGGNVHAVEINPVSFAYLEKNIEANDLAGRVTPELGDCRERLFGIYDRILMGHFEAPDFLKTALDHAEPGT
VLHVHGVGDRKNDITETLEGAGFTYIISEHKVKKYAGRLWHSVWDVNLI

Specific function: Unknown

COG id: COG2520

COG function: function code R; Predicted methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase trmD family [H]

Homologues:

Organism=Homo sapiens, GI157388919, Length=246, Percent_Identity=31.3008130081301, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003402 [H]

Pfam domain/function: PF02475 Met_10 [H]

EC number: NA

Molecular weight: Translated: 32053; Mature: 32053

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRKISKRSLPNAASEPWVDATRRVYCEGEYAFVPVKEGYPFDGEIPDRRPYSGPGYQR
CCCCCCHHHCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCHHH
MGDTLLLHGDAPTADELAALIAWEKPSCVIHAATHEGVMRTPKASVLFGQPHDVTFREAG
CCCEEEEECCCCCHHHHHHHHEECCCCEEEEECCCCCCCCCCCCEEEECCCCCCEEECCC
ITYTLDPSKVMFSQGNRGEKLRLRSLVKPGERIADMFAGIGYFTLSAALAGGNVHAVEIN
EEEEECCCHHEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PVSFAYLEKNIEANDLAGRVTPELGDCRERLFGIYDRILMGHFEAPDFLKTALDHAEPGT
CCEEEEHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
VLHVHGVGDRKNDITETLEGAGFTYIISEHKVKKYAGRLWHSVWDVNLI
EEEEECCCCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCEECC
>Mature Secondary Structure
MKIRKISKRSLPNAASEPWVDATRRVYCEGEYAFVPVKEGYPFDGEIPDRRPYSGPGYQR
CCCCCCHHHCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCHHH
MGDTLLLHGDAPTADELAALIAWEKPSCVIHAATHEGVMRTPKASVLFGQPHDVTFREAG
CCCEEEEECCCCCHHHHHHHHEECCCCEEEEECCCCCCCCCCCCEEEECCCCCCEEECCC
ITYTLDPSKVMFSQGNRGEKLRLRSLVKPGERIADMFAGIGYFTLSAALAGGNVHAVEIN
EEEEECCCHHEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PVSFAYLEKNIEANDLAGRVTPELGDCRERLFGIYDRILMGHFEAPDFLKTALDHAEPGT
CCEEEEHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
VLHVHGVGDRKNDITETLEGAGFTYIISEHKVKKYAGRLWHSVWDVNLI
EEEEECCCCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]