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The map label for this gene is cdc6

Identifier: 124485227

GI number: 124485227

Start: 377088

End: 378221

Strand: Reverse

Name: cdc6

Synonym: Mlab_0400

Alternate gene names: 124485227

Gene position: 378221-377088 (Counterclockwise)

Preceding gene: 124485228

Following gene: 124485226

Centisome position: 20.95

GC content: 48.15

Gene sequence:

>1134_bases
ATGAAAAAGAATCTGCTTATGTGGGACCAGACCCTTTTCAGAGACATAGAAGTCTTTGAAATCACCTATGTCCCCGAGCA
GTTCGATTACCGTGATGAACAGATTGAACGGCTGGCCTTTGCCGTCAAACCCGCTCTGATGGGCGGAAGTATTCTCAATA
CCATTTGCCGGGGTGTTCCAGGGACCGGTAAAACCACCTCAGTGAAGAAATTTTTCGAAGAGATCGAAGAGGCAACGAAA
AAGATCGTGCCGATCCATATCAACTGTCAGATCGACAGCACCGAGTATGCGGTTTTTTCCCGGATATATACAAAACTGAC
GAAAAACAGCCCTCCCTCCTCAGGGACGGCCTTCAAGGTCCTCATCGACATGCTCGCAAAATACATCGAAAAAGAGGGCG
TGATCCCGCTCATCTGTCTGGACGATGCGAACTATCTCATATACAATAAAGAGTTCAACAATGTCCTTTATGCAGCCCTC
CGTATCCACGAAGTATACGAAAACATAGGAATAGGAGTGATCGTTGTCATCAGCGATCCAGATATTCTTCTTGAATCCGT
ACTCGATGCAAGAGTCGCATCCGTTTTCAGGTACGAAACGATCAATTTCGCACCTTACAGTGCCTCGGAAGTCGCCGGAA
TCCTTTCACAGAGAGTTGCCCAGGGCCTGTACCCGAACGTCCTTTCTTCCGAACAACTGGACTACATCGTGGATCGGACA
ATGCGATGCGGGGATATCAGGGTTGGTCTTGATCTGATCAAACGTGCCGTTATGTATGCGGAAACGGATGCACGAAGAGA
GGTCACGCAGGAAGATCTGCAGAAAGCCTTTTCCGCCTCCCAGGACCTGCATCTCTCGGGGACACTCAGATCGCTTTCAT
CTGATGAACTGCTTGTTTTCAGACAACTGGTGAAGATGACGAACGACAATACGCTCATCACAACGGGGGACATCAGAAGA
GCGATGCCGGATGATGCACCGAAACTCACCAGATTCAACGAGATCATCGAAAAGTTCGATCACCTGCGGTTGATTACGCT
TGGATATGCTAACAAAGGGAGCGGAAGAAAACGGTATGTGAACCTCAGATACGATAAAGAACGGGTCAACAAGCTTCTTC
AGAAGAAGAACTGA

Upstream 100 bases:

>100_bases
TGTGAAAAATGCGGCGTTTCGATATCCAAAGTGCAAAGAGATGTCTCCAATCTCTTTATGGGGAAGACTCTCTGTAAAAA
ATGCATGAAATGAGGGGAAA

Downstream 100 bases:

>100_bases
CAGGGAAATTCCGACTCATAACTCTTATCTATTTGACGGTTCCATATCTGACTAATATTCCTTAGGGTGATTTATTTTGG
TAAGTGTAAACGAACTTGGA

Product: cell division control protein 6

Products: NA

Alternate protein names: CDC6 homolog 5 [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKKNLLMWDQTLFRDIEVFEITYVPEQFDYRDEQIERLAFAVKPALMGGSILNTICRGVPGTGKTTSVKKFFEEIEEATK
KIVPIHINCQIDSTEYAVFSRIYTKLTKNSPPSSGTAFKVLIDMLAKYIEKEGVIPLICLDDANYLIYNKEFNNVLYAAL
RIHEVYENIGIGVIVVISDPDILLESVLDARVASVFRYETINFAPYSASEVAGILSQRVAQGLYPNVLSSEQLDYIVDRT
MRCGDIRVGLDLIKRAVMYAETDARREVTQEDLQKAFSASQDLHLSGTLRSLSSDELLVFRQLVKMTNDNTLITTGDIRR
AMPDDAPKLTRFNEIIEKFDHLRLITLGYANKGSGRKRYVNLRYDKERVNKLLQKKN

Sequences:

>Translated_377_residues
MKKNLLMWDQTLFRDIEVFEITYVPEQFDYRDEQIERLAFAVKPALMGGSILNTICRGVPGTGKTTSVKKFFEEIEEATK
KIVPIHINCQIDSTEYAVFSRIYTKLTKNSPPSSGTAFKVLIDMLAKYIEKEGVIPLICLDDANYLIYNKEFNNVLYAAL
RIHEVYENIGIGVIVVISDPDILLESVLDARVASVFRYETINFAPYSASEVAGILSQRVAQGLYPNVLSSEQLDYIVDRT
MRCGDIRVGLDLIKRAVMYAETDARREVTQEDLQKAFSASQDLHLSGTLRSLSSDELLVFRQLVKMTNDNTLITTGDIRR
AMPDDAPKLTRFNEIIEKFDHLRLITLGYANKGSGRKRYVNLRYDKERVNKLLQKKN
>Mature_377_residues
MKKNLLMWDQTLFRDIEVFEITYVPEQFDYRDEQIERLAFAVKPALMGGSILNTICRGVPGTGKTTSVKKFFEEIEEATK
KIVPIHINCQIDSTEYAVFSRIYTKLTKNSPPSSGTAFKVLIDMLAKYIEKEGVIPLICLDDANYLIYNKEFNNVLYAAL
RIHEVYENIGIGVIVVISDPDILLESVLDARVASVFRYETINFAPYSASEVAGILSQRVAQGLYPNVLSSEQLDYIVDRT
MRCGDIRVGLDLIKRAVMYAETDARREVTQEDLQKAFSASQDLHLSGTLRSLSSDELLVFRQLVKMTNDNTLITTGDIRR
AMPDDAPKLTRFNEIIEKFDHLRLITLGYANKGSGRKRYVNLRYDKERVNKLLQKKN

Specific function: Might be involved in the initiation of DNA replication [H]

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family [H]

Homologues:

Organism=Homo sapiens, GI4502703, Length=283, Percent_Identity=23.321554770318, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C [H]

EC number: NA

Molecular weight: Translated: 42980; Mature: 42980

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNLLMWDQTLFRDIEVFEITYVPEQFDYRDEQIERLAFAVKPALMGGSILNTICRGVP
CCCCCEEHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
GTGKTTSVKKFFEEIEEATKKIVPIHINCQIDSTEYAVFSRIYTKLTKNSPPSSGTAFKV
CCCCCHHHHHHHHHHHHHHHCEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHH
LIDMLAKYIEKEGVIPLICLDDANYLIYNKEFNNVLYAALRIHEVYENIGIGVIVVISDP
HHHHHHHHHHHCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEECCC
DILLESVLDARVASVFRYETINFAPYSASEVAGILSQRVAQGLYPNVLSSEQLDYIVDRT
HHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
MRCGDIRVGLDLIKRAVMYAETDARREVTQEDLQKAFSASQDLHLSGTLRSLSSDELLVF
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCHHHHH
RQLVKMTNDNTLITTGDIRRAMPDDAPKLTRFNEIIEKFDHLRLITLGYANKGSGRKRYV
HHHHHHCCCCEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEE
NLRYDKERVNKLLQKKN
EEEECHHHHHHHHHCCC
>Mature Secondary Structure
MKKNLLMWDQTLFRDIEVFEITYVPEQFDYRDEQIERLAFAVKPALMGGSILNTICRGVP
CCCCCEEHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
GTGKTTSVKKFFEEIEEATKKIVPIHINCQIDSTEYAVFSRIYTKLTKNSPPSSGTAFKV
CCCCCHHHHHHHHHHHHHHHCEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHH
LIDMLAKYIEKEGVIPLICLDDANYLIYNKEFNNVLYAALRIHEVYENIGIGVIVVISDP
HHHHHHHHHHHCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEECCC
DILLESVLDARVASVFRYETINFAPYSASEVAGILSQRVAQGLYPNVLSSEQLDYIVDRT
HHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
MRCGDIRVGLDLIKRAVMYAETDARREVTQEDLQKAFSASQDLHLSGTLRSLSSDELLVF
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCHHHHH
RQLVKMTNDNTLITTGDIRRAMPDDAPKLTRFNEIIEKFDHLRLITLGYANKGSGRKRYV
HHHHHHCCCCEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEE
NLRYDKERVNKLLQKKN
EEEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA