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The map label for this gene is ribB

Identifier: 124485223

GI number: 124485223

Start: 372850

End: 373509

Strand: Reverse

Name: ribB

Synonym: Mlab_0396

Alternate gene names: 124485223

Gene position: 373509-372850 (Counterclockwise)

Preceding gene: 124485224

Following gene: 124485222

Centisome position: 20.69

GC content: 51.52

Gene sequence:

>660_bases
ATGTTTACATTTAACACGATCGAAGAGGCCCTGAAATCCCTTCAAAACGGAGAGATGATCATCGTCACCGATGATGAGAA
CCGAGAGAACGAAGGTGACCTGATCTGTGCCGCCGAATATGCCACGACGGAAAATGTCAACTTCATGGCAAAATACGGCA
GAGGGCTGATCTGCATGCCGATGGGACGCAGTCTCGTCGAAAAACTTTGTCTCCCGCCGATGGTGCTCAAAAACACCGAC
AACCACGAAACGGCATTCACGGTCTCCATCGATCATGTCGATACCACTACAGGCATCTCGGCGGTTGAACGCGGCATCAC
CGCACGGAAATGTATCGACCCAAACGCACGGCCGGAGGATTTTCGAAGACCCGGCCATATGTTCCCGCTGCAGGCAAAGG
ACAATGGTGTATTCGAGCGTGAGGGACATACGGAAGCAACCGTCGATCTGATGAAACTGGCAGGACTCAGAGAAGCAGGA
CTCTGCTGCGAGATCATGGCGGACAACGGTGAAATGATGCGGACCCCTGAGCTTATTTCGATGGCCAAGCAGTATAACTT
AACCTTTGTGACCATCAAAGACCTCCAGGCCTACCGGAGAAAGCAGGAAGCTTCGGCTCTTGCCGTTGAACAGAAAAATA
TGAGTCCAATGGACTGTTAA

Upstream 100 bases:

>100_bases
TTGGAAAATACGTCGAACGGTTCATTGCCAAAAGACAGAAGAATGAACCGCAGAAGTGCGTCATAACCGAGGAATACCTC
AGCAAAGCAGGATTTTAGCT

Downstream 100 bases:

>100_bases
GGAGATTATCATGAAAGTTTACGAAGGAAATCTGGTTTCAAAAAACATCAAAATAGGTATCGTTGCTGCAAGATTCAATG
AATTTATCGTATCGAAATTA

Product: aldehyde ferredoxin oxidoreductase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MFTFNTIEEALKSLQNGEMIIVTDDENRENEGDLICAAEYATTENVNFMAKYGRGLICMPMGRSLVEKLCLPPMVLKNTD
NHETAFTVSIDHVDTTTGISAVERGITARKCIDPNARPEDFRRPGHMFPLQAKDNGVFEREGHTEATVDLMKLAGLREAG
LCCEIMADNGEMMRTPELISMAKQYNLTFVTIKDLQAYRRKQEASALAVEQKNMSPMDC

Sequences:

>Translated_219_residues
MFTFNTIEEALKSLQNGEMIIVTDDENRENEGDLICAAEYATTENVNFMAKYGRGLICMPMGRSLVEKLCLPPMVLKNTD
NHETAFTVSIDHVDTTTGISAVERGITARKCIDPNARPEDFRRPGHMFPLQAKDNGVFEREGHTEATVDLMKLAGLREAG
LCCEIMADNGEMMRTPELISMAKQYNLTFVTIKDLQAYRRKQEASALAVEQKNMSPMDC
>Mature_219_residues
MFTFNTIEEALKSLQNGEMIIVTDDENRENEGDLICAAEYATTENVNFMAKYGRGLICMPMGRSLVEKLCLPPMVLKNTD
NHETAFTVSIDHVDTTTGISAVERGITARKCIDPNARPEDFRRPGHMFPLQAKDNGVFEREGHTEATVDLMKLAGLREAG
LCCEIMADNGEMMRTPELISMAKQYNLTFVTIKDLQAYRRKQEASALAVEQKNMSPMDC

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=204, Percent_Identity=46.078431372549, Blast_Score=189, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6320695, Length=207, Percent_Identity=39.6135265700483, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_METLZ (A2SQG6)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001029839.1
- ProteinModelPortal:   A2SQG6
- SMR:   A2SQG6
- STRING:   A2SQG6
- GeneID:   4794681
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_0396
- eggNOG:   arNOG05755
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- ProtClustDB:   CLSK964676
- BioCyc:   MLAB410358:MLAB_0396-MONOMER
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 24522; Mature: 24522

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: BINDING 33-33 BINDING 164-164

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTFNTIEEALKSLQNGEMIIVTDDENRENEGDLICAAEYATTENVNFMAKYGRGLICMP
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHCCCEEEEC
MGRSLVEKLCLPPMVLKNTDNHETAFTVSIDHVDTTTGISAVERGITARKCIDPNARPED
CCHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCHHH
FRRPGHMFPLQAKDNGVFEREGHTEATVDLMKLAGLREAGLCCEIMADNGEMMRTPELIS
HCCCCCEEEEECCCCCCEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEECHHHHH
MAKQYNLTFVTIKDLQAYRRKQEASALAVEQKNMSPMDC
HHHHCCEEEEEHHHHHHHHHHHHHHHHEECCCCCCCCCC
>Mature Secondary Structure
MFTFNTIEEALKSLQNGEMIIVTDDENRENEGDLICAAEYATTENVNFMAKYGRGLICMP
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHCCCEEEEC
MGRSLVEKLCLPPMVLKNTDNHETAFTVSIDHVDTTTGISAVERGITARKCIDPNARPED
CCHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCHHH
FRRPGHMFPLQAKDNGVFEREGHTEATVDLMKLAGLREAGLCCEIMADNGEMMRTPELIS
HCCCCCEEEEECCCCCCEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEECHHHHH
MAKQYNLTFVTIKDLQAYRRKQEASALAVEQKNMSPMDC
HHHHCCEEEEEHHHHHHHHHHHHHHHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA