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The map label for this gene is surE

Identifier: 124485102

GI number: 124485102

Start: 255002

End: 255793

Strand: Reverse

Name: surE

Synonym: Mlab_0275

Alternate gene names: 124485102

Gene position: 255793-255002 (Counterclockwise)

Preceding gene: 124485103

Following gene: 124485097

Centisome position: 14.17

GC content: 50.13

Gene sequence:

>792_bases
ATGCCACGACCAAAAATACTCTTAACGAACGACGACGGGATCAACTCAGGCGGCCTCTGGGCTGCATACGACGCCATGTC
CCTATTCGCTGACGTTACGGTCGTCGCGCCGGCAACCCAGCAAAGCGCGGTCGGCAGATCGATATCGATCTTCGAGCCGT
TAAGGATGAACGAGGTTACCATGCACGGAACGCAGGCATACACCGTTGAAGGGCGTCCAACAGATGCACTTCTTCTCGGC
CTCTACGGACTTGGACTTAGACCGGATCTTGTGGTCTCCGGCATTAATCTGGGAGAAAACATCTCATTTGAATCGATCAC
GACTTCAGGCACCGTGGGTGCTGCGATGGAAGCGGTCAATCAGGGCGTTCCCGCAATCGCATATTCACTTCAAATGAATG
ATGAGGGAAACAAATTTGCTGACCCAAGGTCCCATACGACGGATTTCACCCAGAGCAAAGACGTCGTCACAAAATTCACC
AGACTCTTTCTGGAAAAGGGGATGCCACCGGAGAGCAAACTGATCAATATCAATATCCCGGCGGAAAAAATCGAGGGCTA
TAAAGTAACCGTACTTGGCGAACGGTTGTTTGAAACATCCGTCGAAAAAAGAATCGATCCAAGAGGAAAACCCTACTATT
GGATCAACGGAACACCGATCTACATCCCGGAAGAACACTCGGACGTGACGGCACTCAGGAAAAATTATGTCTCGGTCACG
CCGCTCTCTATGGACAACACCGCATTCAAGGCATGTCCCGAGCTGAAAAAAATGATTTTGGATATCGATTAA

Upstream 100 bases:

>100_bases
GGACGCATGTAAATATCATAGCAAATACGAATTCTTTTATAGGGAGAATTGGCCGAACCCAAAGGTGTAATACCTCACCA
ATGAAACGTATCTGAGAAGA

Downstream 100 bases:

>100_bases
CAGATCCGGGAAACAACCGTTGCCACATATTTGCCGAAATACTCGGCCTGCAGAAGATCGTTCTCGGTAAGCTGACCGTC
GGCAGCAAGTCCGTAATGCC

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MPRPKILLTNDDGINSGGLWAAYDAMSLFADVTVVAPATQQSAVGRSISIFEPLRMNEVTMHGTQAYTVEGRPTDALLLG
LYGLGLRPDLVVSGINLGENISFESITTSGTVGAAMEAVNQGVPAIAYSLQMNDEGNKFADPRSHTTDFTQSKDVVTKFT
RLFLEKGMPPESKLININIPAEKIEGYKVTVLGERLFETSVEKRIDPRGKPYYWINGTPIYIPEEHSDVTALRKNYVSVT
PLSMDNTAFKACPELKKMILDID

Sequences:

>Translated_263_residues
MPRPKILLTNDDGINSGGLWAAYDAMSLFADVTVVAPATQQSAVGRSISIFEPLRMNEVTMHGTQAYTVEGRPTDALLLG
LYGLGLRPDLVVSGINLGENISFESITTSGTVGAAMEAVNQGVPAIAYSLQMNDEGNKFADPRSHTTDFTQSKDVVTKFT
RLFLEKGMPPESKLININIPAEKIEGYKVTVLGERLFETSVEKRIDPRGKPYYWINGTPIYIPEEHSDVTALRKNYVSVT
PLSMDNTAFKACPELKKMILDID
>Mature_262_residues
PRPKILLTNDDGINSGGLWAAYDAMSLFADVTVVAPATQQSAVGRSISIFEPLRMNEVTMHGTQAYTVEGRPTDALLLGL
YGLGLRPDLVVSGINLGENISFESITTSGTVGAAMEAVNQGVPAIAYSLQMNDEGNKFADPRSHTTDFTQSKDVVTKFTR
LFLEKGMPPESKLININIPAEKIEGYKVTVLGERLFETSVEKRIDPRGKPYYWINGTPIYIPEEHSDVTALRKNYVSVTP
LSMDNTAFKACPELKKMILDID

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=253, Percent_Identity=36.3636363636364, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_METLZ (A2SQ45)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001029718.1
- ProteinModelPortal:   A2SQ45
- SMR:   A2SQ45
- STRING:   A2SQ45
- GeneID:   4795439
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_0275
- eggNOG:   arNOG05083
- HOGENOM:   HBG600532
- OMA:   SINVIYS
- PhylomeDB:   A2SQ45
- ProtClustDB:   PRK00346
- BioCyc:   MLAB410358:MLAB_0275-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28834; Mature: 28703

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPKILLTNDDGINSGGLWAAYDAMSLFADVTVVAPATQQSAVGRSISIFEPLRMNEVT
CCCCCEEEECCCCCCCCCEEHHHHHHHHHHCEEEEECCCHHHHCCCEEEEECCCCCCEEE
MHGTQAYTVEGRPTDALLLGLYGLGLRPDLVVSGINLGENISFESITTSGTVGAAMEAVN
EECCEEEEECCCCCHHHEEEHHCCCCCCCCEEECCCCCCCCCCCEEECCCCHHHHHHHHH
QGVPAIAYSLQMNDEGNKFADPRSHTTDFTQSKDVVTKFTRLFLEKGMPPESKLININIP
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECC
AEKIEGYKVTVLGERLFETSVEKRIDPRGKPYYWINGTPIYIPEEHSDVTALRKNYVSVT
HHHHCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCHHHHHHHCCEEEE
PLSMDNTAFKACPELKKMILDID
ECCCCCHHHHHCHHHHHHHCCCC
>Mature Secondary Structure 
PRPKILLTNDDGINSGGLWAAYDAMSLFADVTVVAPATQQSAVGRSISIFEPLRMNEVT
CCCCEEEECCCCCCCCCEEHHHHHHHHHHCEEEEECCCHHHHCCCEEEEECCCCCCEEE
MHGTQAYTVEGRPTDALLLGLYGLGLRPDLVVSGINLGENISFESITTSGTVGAAMEAVN
EECCEEEEECCCCCHHHEEEHHCCCCCCCCEEECCCCCCCCCCCEEECCCCHHHHHHHHH
QGVPAIAYSLQMNDEGNKFADPRSHTTDFTQSKDVVTKFTRLFLEKGMPPESKLININIP
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECC
AEKIEGYKVTVLGERLFETSVEKRIDPRGKPYYWINGTPIYIPEEHSDVTALRKNYVSVT
HHHHCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCHHHHHHHCCEEEE
PLSMDNTAFKACPELKKMILDID
ECCCCCHHHHHCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA