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The map label for this gene is cpx [H]

Identifier: 124485009

GI number: 124485009

Start: 168098

End: 169687

Strand: Reverse

Name: cpx [H]

Synonym: Mlab_0182

Alternate gene names: 124485009

Gene position: 169687-168098 (Counterclockwise)

Preceding gene: 124485011

Following gene: 124485007

Centisome position: 9.4

GC content: 54.03

Gene sequence:

>1590_bases
ATGTTCACAATGGCCGAGGGGGATGAACCGATCTACAATGTCAAAGACAACGTACCGCTTGGAACGACGGTTCTGACAAT
CCTCCAGCATTTCTTTGTTTTAGCCGTGTATATGACATATCCGGTGATCATCAGCAATGCGATCGGCGGCTCGACGGATC
TGACAATGTTTCTGATCAGTGCGACCCTGATCGGCTCGGGTATCGCGACGATCCTGCAGTCTTTTTCGAAGACGGGGGCA
GGATATCTTCTGCCGATGGTCCCAAACTCTTCGTATCTGCCGGCTTCCCTTCTTGCTGCAACGGCCGGAGGACTGCCCCT
TCTGTATGGAATGCTGATCATCTCAGGACTGTTCGAGATGGTGATCAGCCGGTTCACGACGTTTTTCCGGATCGTGTTCC
CAAACGAAGTGACGGGTGTTGTGCTGTTCCTTCTGGGGATCGCTATCGTTCCGTTCGCATTTCCGCTGTTTTTCGGAAGC
ACGGACTCAGGACCCCTGGACCCGGCATCAACGGTCGTGGGCATCATTACGCTGACCTCCACGATCCTTTTGAGTGTGAT
CCCGAAACGGTTCTTCAAGTTCTATGCTATCCTGATCGGTATCGTGATCGGGATGGCGGCATCCGTGTTTCTGGGCGTGT
TCAAACTCGAGACCCTGCTCCAAATCACGAGCCTTTCGGTGTTCTGGATCCCGAACCCAATCGGGATCGTCTCGTATTCG
TTCGAATTCGCGCTGCTGATCCCGTTTGCGATCGCGATGATCTGCGTGATGCTGAAGTCGGTCGGAAACATTTCGCTCCT
GAACGCCTACACCAAAGAGGGCGAGAAGAATACGCTGAAAAACGGGCTGATGTCGGAGGGTGCGGGGGTCGCGATCGCCG
GAGCGTTGGGCGGGATCGGGATCGGATCGTCTTCGGGAGCGACGGGGCTCGTTGTCGGGACCGGGATCGCAGCAAAGCGG
GTTGGGTTGGGTCTTGGGATCTTTCTGATCCTGTGCGGATTTTTGCCGGCGATCGGCTGGGTTTTTCATATTCTCCCTAA
GCCGATCCTTGGAGCGACCCTTTTGTATGCGGTGACGTTTGTGATGGTGACCGGCATCCAGAGTATTTCGTCACGGATGC
TTGATCCCCGGCGAAAGTTCGTGGTGATCCTGCCGATTTTGATCGGGGTCTCGTCGGCTGTGTGTCCGTATCTGTATGCT
GACCTCCCGAAGACGTTGGCACTGTTCTTTGCATCGCCGCTGACGTCCGGGTCGATGGCGGTTTTGATTCTCGGTCTTCT
ACTCAGAATCGGTATCAAAAAGCACCGGTCGTTCGATTTTTCGAAGGATGCGAATCTGCAGAGGTTCCTGATGGAATGCG
GACGTCAGTGGACGCTTGAACGTATGCAGATGTTGTCGATTTCAAATCATCTGCAGAATCTGGCGGATGCCGGAGAGCCG
GAGAGGCTGGAAATGAAGTTCGAACCGATCGGGATGCTTAGAGCAGAGATGGTTTTCAAAGAGCCGGTGGAGAATGTCCC
GAAGATGAAAATAAACGGGAATCTGGAGGCGGATGGGAGAGTGGTTAAAGCAAGCTATCCGCTGATGTAG

Upstream 100 bases:

>100_bases
AAATTCCTCCTTCTCATACATAGGATAGCTATTTTGTATGTCTGAAAGTGTGATAATCCTATTCCTACGATAAGCTTTAA
CATAAAAGTACAACCAACAA

Downstream 100 bases:

>100_bases
GGAGATAACGTTCTTCCACAATATTATCTCGTTTGGAAAATTGCACAAATCGAAACCTCTTGAAGATTAATACCAAGTCT
TTGGTTTGCTCCCATAAGGA

Product: aminoacyl-tRNA synthetase, class Ia

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MFTMAEGDEPIYNVKDNVPLGTTVLTILQHFFVLAVYMTYPVIISNAIGGSTDLTMFLISATLIGSGIATILQSFSKTGA
GYLLPMVPNSSYLPASLLAATAGGLPLLYGMLIISGLFEMVISRFTTFFRIVFPNEVTGVVLFLLGIAIVPFAFPLFFGS
TDSGPLDPASTVVGIITLTSTILLSVIPKRFFKFYAILIGIVIGMAASVFLGVFKLETLLQITSLSVFWIPNPIGIVSYS
FEFALLIPFAIAMICVMLKSVGNISLLNAYTKEGEKNTLKNGLMSEGAGVAIAGALGGIGIGSSSGATGLVVGTGIAAKR
VGLGLGIFLILCGFLPAIGWVFHILPKPILGATLLYAVTFVMVTGIQSISSRMLDPRRKFVVILPILIGVSSAVCPYLYA
DLPKTLALFFASPLTSGSMAVLILGLLLRIGIKKHRSFDFSKDANLQRFLMECGRQWTLERMQMLSISNHLQNLADAGEP
ERLEMKFEPIGMLRAEMVFKEPVENVPKMKINGNLEADGRVVKASYPLM

Sequences:

>Translated_529_residues
MFTMAEGDEPIYNVKDNVPLGTTVLTILQHFFVLAVYMTYPVIISNAIGGSTDLTMFLISATLIGSGIATILQSFSKTGA
GYLLPMVPNSSYLPASLLAATAGGLPLLYGMLIISGLFEMVISRFTTFFRIVFPNEVTGVVLFLLGIAIVPFAFPLFFGS
TDSGPLDPASTVVGIITLTSTILLSVIPKRFFKFYAILIGIVIGMAASVFLGVFKLETLLQITSLSVFWIPNPIGIVSYS
FEFALLIPFAIAMICVMLKSVGNISLLNAYTKEGEKNTLKNGLMSEGAGVAIAGALGGIGIGSSSGATGLVVGTGIAAKR
VGLGLGIFLILCGFLPAIGWVFHILPKPILGATLLYAVTFVMVTGIQSISSRMLDPRRKFVVILPILIGVSSAVCPYLYA
DLPKTLALFFASPLTSGSMAVLILGLLLRIGIKKHRSFDFSKDANLQRFLMECGRQWTLERMQMLSISNHLQNLADAGEP
ERLEMKFEPIGMLRAEMVFKEPVENVPKMKINGNLEADGRVVKASYPLM
>Mature_529_residues
MFTMAEGDEPIYNVKDNVPLGTTVLTILQHFFVLAVYMTYPVIISNAIGGSTDLTMFLISATLIGSGIATILQSFSKTGA
GYLLPMVPNSSYLPASLLAATAGGLPLLYGMLIISGLFEMVISRFTTFFRIVFPNEVTGVVLFLLGIAIVPFAFPLFFGS
TDSGPLDPASTVVGIITLTSTILLSVIPKRFFKFYAILIGIVIGMAASVFLGVFKLETLLQITSLSVFWIPNPIGIVSYS
FEFALLIPFAIAMICVMLKSVGNISLLNAYTKEGEKNTLKNGLMSEGAGVAIAGALGGIGIGSSSGATGLVVGTGIAAKR
VGLGLGIFLILCGFLPAIGWVFHILPKPILGATLLYAVTFVMVTGIQSISSRMLDPRRKFVVILPILIGVSSAVCPYLYA
DLPKTLALFFASPLTSGSMAVLILGLLLRIGIKKHRSFDFSKDANLQRFLMECGRQWTLERMQMLSISNHLQNLADAGEP
ERLEMKFEPIGMLRAEMVFKEPVENVPKMKINGNLEADGRVVKASYPLM

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790087, Length=444, Percent_Identity=23.1981981981982, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87082178, Length=451, Percent_Identity=23.7250554323725, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082181, Length=465, Percent_Identity=23.8709677419355, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17558856, Length=428, Percent_Identity=24.2990654205607, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 56803; Mature: 56803

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTMAEGDEPIYNVKDNVPLGTTVLTILQHFFVLAVYMTYPVIISNAIGGSTDLTMFLIS
CCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ATLIGSGIATILQSFSKTGAGYLLPMVPNSSYLPASLLAATAGGLPLLYGMLIISGLFEM
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
VISRFTTFFRIVFPNEVTGVVLFLLGIAIVPFAFPLFFGSTDSGPLDPASTVVGIITLTS
HHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
TILLSVIPKRFFKFYAILIGIVIGMAASVFLGVFKLETLLQITSLSVFWIPNPIGIVSYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEH
FEFALLIPFAIAMICVMLKSVGNISLLNAYTKEGEKNTLKNGLMSEGAGVAIAGALGGIG
HHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCHHHHHHHHHCCCCCEEEEEHHCCCC
IGSSSGATGLVVGTGIAAKRVGLGLGIFLILCGFLPAIGWVFHILPKPILGATLLYAVTF
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VMVTGIQSISSRMLDPRRKFVVILPILIGVSSAVCPYLYADLPKTLALFFASPLTSGSMA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
VLILGLLLRIGIKKHRSFDFSKDANLQRFLMECGRQWTLERMQMLSISNHLQNLADAGEP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
ERLEMKFEPIGMLRAEMVFKEPVENVPKMKINGNLEADGRVVKASYPLM
CEEEEEECCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MFTMAEGDEPIYNVKDNVPLGTTVLTILQHFFVLAVYMTYPVIISNAIGGSTDLTMFLIS
CCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ATLIGSGIATILQSFSKTGAGYLLPMVPNSSYLPASLLAATAGGLPLLYGMLIISGLFEM
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
VISRFTTFFRIVFPNEVTGVVLFLLGIAIVPFAFPLFFGSTDSGPLDPASTVVGIITLTS
HHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
TILLSVIPKRFFKFYAILIGIVIGMAASVFLGVFKLETLLQITSLSVFWIPNPIGIVSYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEH
FEFALLIPFAIAMICVMLKSVGNISLLNAYTKEGEKNTLKNGLMSEGAGVAIAGALGGIG
HHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCHHHHHHHHHCCCCCEEEEEHHCCCC
IGSSSGATGLVVGTGIAAKRVGLGLGIFLILCGFLPAIGWVFHILPKPILGATLLYAVTF
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VMVTGIQSISSRMLDPRRKFVVILPILIGVSSAVCPYLYADLPKTLALFFASPLTSGSMA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
VLILGLLLRIGIKKHRSFDFSKDANLQRFLMECGRQWTLERMQMLSISNHLQNLADAGEP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
ERLEMKFEPIGMLRAEMVFKEPVENVPKMKINGNLEADGRVVKASYPLM
CEEEEEECCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11792842; 8162194 [H]