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The map label for this gene is uppS [H]

Identifier: 124484953

GI number: 124484953

Start: 113700

End: 114293

Strand: Reverse

Name: uppS [H]

Synonym: Mlab_0125

Alternate gene names: 124484953

Gene position: 114293-113700 (Counterclockwise)

Preceding gene: 124484967

Following gene: 124484952

Centisome position: 6.33

GC content: 47.47

Gene sequence:

>594_bases
ATGATATACCGCCTCTATGAGTACCTGATTTCCCGAGACCTCACAACATTTCCAAAAGAGATATGTTTCATGCTGAGCGA
TGAGGATGTACTTTTCGATGCGGGGAAAATAGAGGCGGTCTATACCTGGACAAAAGAGTTCCCAGACATCAAAAAGATCA
TTTTCCACATCAGTACGGATGATCCCCGGCGAATCGAGGGACTGCTTGGACTCGAAGAACTTGGAAAGAAAACGACCGTA
CGGGTAAGTACGCCCGAACACGACACGATAATCGGAACCGGAATTCCAGAGATCCTGATCGCTCTTGGCAAAACCGGAAG
GGAAGAGATCACCGACGCGATCATCAAAATCGCAAAAGAGGGTGTGGAGCCTAATGAAATCACGGAAGATATGATAGAGA
AACATCTCATATTTCACGTGAACCCGGATTTTGTGATAAAAACCGGAGGGAATCACCTCACCGACTTTTTGATCTGGCAG
TCGGTGTATTCGGAACTTTTTTTTACCGACATCAACTGGGGCGGCTTTCGAAAAGTAGACTATCTTAGGGCGCTTCGCGA
TTATCAGTCCCGGGGCCGGCGATACGGGACATGA

Upstream 100 bases:

>100_bases
TTTTTAGTATGTATCTGTGTATATAAATAAATACCGCTCAAACAAGTATAAAATAATACACGAATTTGATATGCAGAGAA
AAGCAATAGAGTAATACCTC

Downstream 100 bases:

>100_bases
AAGAAAGCCGAAGGGGAAAACATCTATATACTTCTCATAGATGAATAAGATACTACAACAATGTCACTTTCCATTCCAAA
ATTACCCGAATCGAAAGATC

Product: ATP-dependent carboligase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIYRLYEYLISRDLTTFPKEICFMLSDEDVLFDAGKIEAVYTWTKEFPDIKKIIFHISTDDPRRIEGLLGLEELGKKTTV
RVSTPEHDTIIGTGIPEILIALGKTGREEITDAIIKIAKEGVEPNEITEDMIEKHLIFHVNPDFVIKTGGNHLTDFLIWQ
SVYSELFFTDINWGGFRKVDYLRALRDYQSRGRRYGT

Sequences:

>Translated_197_residues
MIYRLYEYLISRDLTTFPKEICFMLSDEDVLFDAGKIEAVYTWTKEFPDIKKIIFHISTDDPRRIEGLLGLEELGKKTTV
RVSTPEHDTIIGTGIPEILIALGKTGREEITDAIIKIAKEGVEPNEITEDMIEKHLIFHVNPDFVIKTGGNHLTDFLIWQ
SVYSELFFTDINWGGFRKVDYLRALRDYQSRGRRYGT
>Mature_197_residues
MIYRLYEYLISRDLTTFPKEICFMLSDEDVLFDAGKIEAVYTWTKEFPDIKKIIFHISTDDPRRIEGLLGLEELGKKTTV
RVSTPEHDTIIGTGIPEILIALGKTGREEITDAIIKIAKEGVEPNEITEDMIEKHLIFHVNPDFVIKTGGNHLTDFLIWQ
SVYSELFFTDINWGGFRKVDYLRALRDYQSRGRRYGT

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is probably the precursor of glycosyl carrier lipids [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786371, Length=123, Percent_Identity=35.7723577235772, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 22809; Mature: 22809

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYRLYEYLISRDLTTFPKEICFMLSDEDVLFDAGKIEAVYTWTKEFPDIKKIIFHISTD
CHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEECHHCCHHHHHEEECCCC
DPRRIEGLLGLEELGKKTTVRVSTPEHDTIIGTGIPEILIALGKTGREEITDAIIKIAKE
CHHHHHHHHCHHHCCCCCEEEEECCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHC
GVEPNEITEDMIEKHLIFHVNPDFVIKTGGNHLTDFLIWQSVYSELFFTDINWGGFRKVD
CCCHHHHHHHHHHHHEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHH
YLRALRDYQSRGRRYGT
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIYRLYEYLISRDLTTFPKEICFMLSDEDVLFDAGKIEAVYTWTKEFPDIKKIIFHISTD
CHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEECHHCCHHHHHEEECCCC
DPRRIEGLLGLEELGKKTTVRVSTPEHDTIIGTGIPEILIALGKTGREEITDAIIKIAKE
CHHHHHHHHCHHHCCCCCEEEEECCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHC
GVEPNEITEDMIEKHLIFHVNPDFVIKTGGNHLTDFLIWQSVYSELFFTDINWGGFRKVD
CCCHHHHHHHHHHHHEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHH
YLRALRDYQSRGRRYGT
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]