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The map label for this gene is mtd

Identifier: 124484908

GI number: 124484908

Start: 82568

End: 83410

Strand: Reverse

Name: mtd

Synonym: Mlab_0079

Alternate gene names: 124484908

Gene position: 83410-82568 (Counterclockwise)

Preceding gene: 124484936

Following gene: 124484904

Centisome position: 4.62

GC content: 53.5

Gene sequence:

>843_bases
ATGGTAGTTAAGGTAGGAGTTGCAAAACTCGGTAACATCGCAGCCGGTGTTATGGCAGAGTTGCTTTTAGATGAGCGTGC
AGACCGTGAAGACATGATGACATTCATGGCAACTTCCGGAACCAAACTGCAGAAGGAAGATGTTGACCGTGTCGTTTCAA
ACCTGAAAGCATGGCAGCCCGACTTCGCAATCGTTGTTTCCCCGAACGGAGTTCTCGAAGGCCCGGTCGGTGCACGCGAG
GACCTCAAAGCAGCAGGTATCCCGACCATCGTTATCACTGACGATGTCACGACCAAGAAAGAAGGCTGGGAAGCACTCAA
GGCATCCGGCTTTGGCTACATCATCGTCAAAGCAGACGCCATGATCGGTGCCCGCCGCGAATTCCTCGACCCAGTCGAGA
TGGCAGACTACAACGGCAACCTTGTGAAAGTCCTTGCCCTTACCGGTGCATTCCGCAAACTCCAGCTGGAGCTTGACAAA
GTCATCGACCAGGTAAAAGCAGGTAAGAAAGGCGCAGAGCTCGAACTCCCGAAACTTGTTCTGAACTCTGACAACTCGAC
CAAAGGCGAGTTCACAAACCCCTATGCACTTGCAAAAGCACGCGCAGCATACGAGATCGCCCAGGCAGTTGCAGGTGTCA
ACGTCAAAGGCTGTTTCATGACCAAAGAGTGGACAGACTACGTACCAATCGTCGCCTCCGCACACGAAATGATGCGTGCA
GCAGCAAACCTTTGTGACCAGGCACGCGAACTCGAGAAGGGATGCGACGGCGTTATCCGCAAGCCGCACAAGAAGACCGG
TGAGATCGTCTCCAAGGTCGCCCTTATCAGCAAGCCCGAGTAA

Upstream 100 bases:

>100_bases
TTGTAGTTATTTGATTTTTGAAGAGTGTCATTCACAAACCTTATATTGATTCTCGTCGATAATCTGATGTTCTCATTTCA
AAATGAGAGGTGTATCAAAT

Downstream 100 bases:

>100_bases
TCAGACACCCAAATTTTACCATTTTTCTTTTTGGATGCAGGGGGAATTACCCCTCTGTATTTAATGATATACAATAATTA
AGATCAGATATATTTTCAAA

Product: F420-dependent methylenetetrahydromethanopterin dehydrogenase

Products: NA

Alternate protein names: MTD; Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MVVKVGVAKLGNIAAGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSNLKAWQPDFAIVVSPNGVLEGPVGARE
DLKAAGIPTIVITDDVTTKKEGWEALKASGFGYIIVKADAMIGARREFLDPVEMADYNGNLVKVLALTGAFRKLQLELDK
VIDQVKAGKKGAELELPKLVLNSDNSTKGEFTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWTDYVPIVASAHEMMRA
AANLCDQARELEKGCDGVIRKPHKKTGEIVSKVALISKPE

Sequences:

>Translated_280_residues
MVVKVGVAKLGNIAAGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSNLKAWQPDFAIVVSPNGVLEGPVGARE
DLKAAGIPTIVITDDVTTKKEGWEALKASGFGYIIVKADAMIGARREFLDPVEMADYNGNLVKVLALTGAFRKLQLELDK
VIDQVKAGKKGAELELPKLVLNSDNSTKGEFTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWTDYVPIVASAHEMMRA
AANLCDQARELEKGCDGVIRKPHKKTGEIVSKVALISKPE
>Mature_280_residues
MVVKVGVAKLGNIAAGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSNLKAWQPDFAIVVSPNGVLEGPVGARE
DLKAAGIPTIVITDDVTTKKEGWEALKASGFGYIIVKADAMIGARREFLDPVEMADYNGNLVKVLALTGAFRKLQLELDK
VIDQVKAGKKGAELELPKLVLNSDNSTKGEFTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWTDYVPIVASAHEMMRA
AANLCDQARELEKGCDGVIRKPHKKTGEIVSKVALISKPE

Specific function: Catalyzes the reversible reduction of methenyl- H(4)MPT(+) to methylene-H(4)MPT

COG id: COG1927

COG function: function code C; Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTD_METLZ (A2SPK1)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001029524.1
- ProteinModelPortal:   A2SPK1
- SMR:   A2SPK1
- STRING:   A2SPK1
- GeneID:   4794919
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_0079
- eggNOG:   arNOG04866
- HOGENOM:   HBG538567
- OMA:   IVASAHE
- ProtClustDB:   PRK00994
- BioCyc:   MLAB410358:MLAB_0079-MONOMER
- GO:   GO:0015948
- HAMAP:   MF_00058
- InterPro:   IPR002844
- ProDom:   PD017604

Pfam domain/function: PF01993 MTD; SSF102324 MeTD

EC number: =1.5.99.9

Molecular weight: Translated: 30248; Mature: 30248

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVKVGVAKLGNIAAGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSNLKAWQP
CEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
DFAIVVSPNGVLEGPVGAREDLKAAGIPTIVITDDVTTKKEGWEALKASGFGYIIVKADA
CEEEEECCCCCEECCCCCHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEECH
MIGARREFLDPVEMADYNGNLVKVLALTGAFRKLQLELDKVIDQVKAGKKGAELELPKLV
HHHHHHHHCCCHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
LNSDNSTKGEFTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWTDYVPIVASAHEMMRA
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
AANLCDQARELEKGCDGVIRKPHKKTGEIVSKVALISKPE
HHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVVKVGVAKLGNIAAGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSNLKAWQP
CEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
DFAIVVSPNGVLEGPVGAREDLKAAGIPTIVITDDVTTKKEGWEALKASGFGYIIVKADA
CEEEEECCCCCEECCCCCHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEECH
MIGARREFLDPVEMADYNGNLVKVLALTGAFRKLQLELDKVIDQVKAGKKGAELELPKLV
HHHHHHHHCCCHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
LNSDNSTKGEFTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWTDYVPIVASAHEMMRA
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
AANLCDQARELEKGCDGVIRKPHKKTGEIVSKVALISKPE
HHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA