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The map label for this gene is dcd [H]

Identifier: 124484904

GI number: 124484904

Start: 78999

End: 79430

Strand: Reverse

Name: dcd [H]

Synonym: Mlab_0075

Alternate gene names: 124484904

Gene position: 79430-78999 (Counterclockwise)

Preceding gene: 124484908

Following gene: 124484902

Centisome position: 4.4

GC content: 46.76

Gene sequence:

>432_bases
ATGGTTCTTTCTTCATCAATAATCAGGACACGCCTTAAAGAGGGATCTCTTGGAATAGATCCTTTCGCCGAAGAATCGCT
GCAGCCCTCCTCATACGATCTCAGAAGCGCTGAAGATATCACAATAACAAAAGGAGAGTTAACCCTCGTTCCAACGATGG
AGTTCGTCAGCCTCCCGGAAGATCTCTGCGCAACACTCTGGGGAAGATCATCGTTCGGGAGAAAAGGCGTCGTTCTTGGA
GCCGGGTATATCGACCCGGGATTTCGCGGGAACCTGACATTATGTATGGCAAATTACGGGCCTGAAGACATCCAGGTAAC
CAAAGGTATGCGAGTCGTACAAATGCTCATCCACACCGTTGAAGGCAAAGTGGAAAATACCTACAACGGAAATTATCAGG
ATAGTTACGGCGTAGTGAAATCAAAAATTTAA

Upstream 100 bases:

>100_bases
GATCGAACCCGGTTCTTCGGGTTCGAAGCCCGAAAGGATATCCACTACCCCACAAGTCCAGAGTTATTAGTATATTTGTG
TCCGATGCGTATTATCTTGT

Downstream 100 bases:

>100_bases
GATACCTAGCGTAAAAAGCATCACCGGGAGCATAATAGCCCCCATACAAAAAATCCTTGGAATATTGATCATCCCGGGAA
TCATGCCGACAAGCGTTGCA

Product: dCTP deaminase

Products: NA

Alternate protein names: dCTP deaminase [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MVLSSSIIRTRLKEGSLGIDPFAEESLQPSSYDLRSAEDITITKGELTLVPTMEFVSLPEDLCATLWGRSSFGRKGVVLG
AGYIDPGFRGNLTLCMANYGPEDIQVTKGMRVVQMLIHTVEGKVENTYNGNYQDSYGVVKSKI

Sequences:

>Translated_143_residues
MVLSSSIIRTRLKEGSLGIDPFAEESLQPSSYDLRSAEDITITKGELTLVPTMEFVSLPEDLCATLWGRSSFGRKGVVLG
AGYIDPGFRGNLTLCMANYGPEDIQVTKGMRVVQMLIHTVEGKVENTYNGNYQDSYGVVKSKI
>Mature_143_residues
MVLSSSIIRTRLKEGSLGIDPFAEESLQPSSYDLRSAEDITITKGELTLVPTMEFVSLPEDLCATLWGRSSFGRKGVVLG
AGYIDPGFRGNLTLCMANYGPEDIQVTKGMRVVQMLIHTVEGKVENTYNGNYQDSYGVVKSKI

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011962
- InterPro:   IPR008180 [H]

Pfam domain/function: PF00692 dUTPase [H]

EC number: =3.5.4.13 [H]

Molecular weight: Translated: 15671; Mature: 15671

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSSSIIRTRLKEGSLGIDPFAEESLQPSSYDLRSAEDITITKGELTLVPTMEFVSLPE
CCCCHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCEEEECCCEEEECCHHHHCCCH
DLCATLWGRSSFGRKGVVLGAGYIDPGFRGNLTLCMANYGPEDIQVTKGMRVVQMLIHTV
HHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHHH
EGKVENTYNGNYQDSYGVVKSKI
CCCCCCCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MVLSSSIIRTRLKEGSLGIDPFAEESLQPSSYDLRSAEDITITKGELTLVPTMEFVSLPE
CCCCHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCEEEECCCEEEECCHHHHCCCH
DLCATLWGRSSFGRKGVVLGAGYIDPGFRGNLTLCMANYGPEDIQVTKGMRVVQMLIHTV
HHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHHH
EGKVENTYNGNYQDSYGVVKSKI
CCCCCCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11782527 [H]