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The map label for this gene is frhB [H]

Identifier: 124484841

GI number: 124484841

Start: 12111

End: 12983

Strand: Reverse

Name: frhB [H]

Synonym: Mlab_0012

Alternate gene names: 124484841

Gene position: 12983-12111 (Counterclockwise)

Preceding gene: 124484842

Following gene: 124484840

Centisome position: 0.72

GC content: 53.49

Gene sequence:

>873_bases
ATGGAATATCTTGGACAATACAAGGCAGTCTACAAAGCCAAAGCCGGCTGTGAAGACATTCTCGCAAAGTCCCAGGACGG
AGGAATCGTCACAGCAATGTTTGCCTACGCACTTGAGACAGGCATTATTGACGGAGCAATCGTCGCAGGACCAGGAGCAG
AGCCGTACAAGCCTGAACCGATGATCGCCACAACGGTCGAAGAACTCTTCGCAAGCCGTGGAACCAAATACTCAGTCTCA
CCGAACCTTGCACTGATCAAAGAGGCAACCCGCAGCTATGGTCTTGACAAGATCGGTATCGTCGGAACCCCATGCCAGAT
CCAGGCAGTGCGCAAAGCACAGCTCTACCCAATCGGTCTGCGTGACGTCCCCGACAAGATCGCTCTTGCACTCGGTATCT
TCTGTATGGAAAACTTCCCCTACCAGGGACTCTTCCAGATGGTCGAAGACCACTGTGCAACCAAGATCGACAATGTCACC
AAGATGGACATCGGAAAGGGCAAATTCTCCGTCTACACCGAGCGCGGTGTAAACTCGCAGATCCCCTTAAAGGTTACTCA
CAAGTATGAGCAGCCCGGATGCCACGTCTGTCTCGACTATGTCGCAAACATGGCAGATATCTCAACCGGTTCCGTTGGAA
CTCCGGACGGATGGTCAACCGTCTTCGTCCGCTCCGCAGCCGGTGAGGCAGCCTTCAACAAGGCAGTCGAAGCAGGCTGG
ATCATTGCCGAGTCAATGGACGGCGTCAAGCCGGGTCTTGAACTCGTCGAGAAGCTTGCAACCGAGAAGATCACCAAAAA
CCAGAAGTACCTTGAGCACAGAGCCCACAAGGAGCACGCAGCTCTCAAACCACTCCGTAACCCCTACATCTAA

Upstream 100 bases:

>100_bases
CGAGAAGCTTCTTCAGCTTCGACGTCTGTGGACAGTATGAAGCAATCACTAACCTCATTGGAGAGGTTATGAAACCCTGA
GGGTCCTGGAGGCGAAAAAA

Downstream 100 bases:

>100_bases
ACAGTGTATAATGGATTACGACATGTACCCATCCTCTCGGGTACACTTTTTTTGAGGAAAATTTTTCCCTAGGGCAAACC
CCAAACGAACATCTTTTCAT

Product: coenzyme F420-reducing hydrogenase subunit beta

Products: NA

Alternate protein names: 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit beta; FRH [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MEYLGQYKAVYKAKAGCEDILAKSQDGGIVTAMFAYALETGIIDGAIVAGPGAEPYKPEPMIATTVEELFASRGTKYSVS
PNLALIKEATRSYGLDKIGIVGTPCQIQAVRKAQLYPIGLRDVPDKIALALGIFCMENFPYQGLFQMVEDHCATKIDNVT
KMDIGKGKFSVYTERGVNSQIPLKVTHKYEQPGCHVCLDYVANMADISTGSVGTPDGWSTVFVRSAAGEAAFNKAVEAGW
IIAESMDGVKPGLELVEKLATEKITKNQKYLEHRAHKEHAALKPLRNPYI

Sequences:

>Translated_290_residues
MEYLGQYKAVYKAKAGCEDILAKSQDGGIVTAMFAYALETGIIDGAIVAGPGAEPYKPEPMIATTVEELFASRGTKYSVS
PNLALIKEATRSYGLDKIGIVGTPCQIQAVRKAQLYPIGLRDVPDKIALALGIFCMENFPYQGLFQMVEDHCATKIDNVT
KMDIGKGKFSVYTERGVNSQIPLKVTHKYEQPGCHVCLDYVANMADISTGSVGTPDGWSTVFVRSAAGEAAFNKAVEAGW
IIAESMDGVKPGLELVEKLATEKITKNQKYLEHRAHKEHAALKPLRNPYI
>Mature_290_residues
MEYLGQYKAVYKAKAGCEDILAKSQDGGIVTAMFAYALETGIIDGAIVAGPGAEPYKPEPMIATTVEELFASRGTKYSVS
PNLALIKEATRSYGLDKIGIVGTPCQIQAVRKAQLYPIGLRDVPDKIALALGIFCMENFPYQGLFQMVEDHCATKIDNVT
KMDIGKGKFSVYTERGVNSQIPLKVTHKYEQPGCHVCLDYVANMADISTGSVGTPDGWSTVFVRSAAGEAAFNKAVEAGW
IIAESMDGVKPGLELVEKLATEKITKNQKYLEHRAHKEHAALKPLRNPYI

Specific function: Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen [H]

COG id: COG1035

COG function: function code C; Coenzyme F420-reducing hydrogenase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frhB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007516
- InterPro:   IPR017679
- InterPro:   IPR007525 [H]

Pfam domain/function: PF04432 FrhB_FdhB_C; PF04422 FrhB_FdhB_N [H]

EC number: =1.12.98.1 [H]

Molecular weight: Translated: 31541; Mature: 31541

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYLGQYKAVYKAKAGCEDILAKSQDGGIVTAMFAYALETGIIDGAIVAGPGAEPYKPEP
CCHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
MIATTVEELFASRGTKYSVSPNLALIKEATRSYGLDKIGIVGTPCQIQAVRKAQLYPIGL
HHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHEEECCC
RDVPDKIALALGIFCMENFPYQGLFQMVEDHCATKIDNVTKMDIGKGKFSVYTERGVNSQ
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCC
IPLKVTHKYEQPGCHVCLDYVANMADISTGSVGTPDGWSTVFVRSAAGEAAFNKAVEAGW
CCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCE
IIAESMDGVKPGLELVEKLATEKITKNQKYLEHRAHKEHAALKPLRNPYI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEYLGQYKAVYKAKAGCEDILAKSQDGGIVTAMFAYALETGIIDGAIVAGPGAEPYKPEP
CCHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
MIATTVEELFASRGTKYSVSPNLALIKEATRSYGLDKIGIVGTPCQIQAVRKAQLYPIGL
HHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHEEECCC
RDVPDKIALALGIFCMENFPYQGLFQMVEDHCATKIDNVTKMDIGKGKFSVYTERGVNSQ
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCC
IPLKVTHKYEQPGCHVCLDYVANMADISTGSVGTPDGWSTVFVRSAAGEAAFNKAVEAGW
CCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCE
IIAESMDGVKPGLELVEKLATEKITKNQKYLEHRAHKEHAALKPLRNPYI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8521835 [H]