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The map label for this gene is yhcK [H]

Identifier: 124266212

GI number: 124266212

Start: 1085404

End: 1086459

Strand: Direct

Name: yhcK [H]

Synonym: Mpe_A1019

Alternate gene names: 124266212

Gene position: 1085404-1086459 (Clockwise)

Preceding gene: 124266211

Following gene: 124266215

Centisome position: 26.84

GC content: 69.51

Gene sequence:

>1056_bases
GTGATCTCAGGCAACTACCCCGACAGTGTCGAGCGGAGCAGCGAACTTCTGAGGCTCGCGCTCCCGCAGATGGCCAAGCA
TTCGGTCGCCCTGCACCCCATCAACTACGCGGTCTGGTACGAGTATGTGTCGGGCCGCAGCAGCGACCTGAAGGCCGAGA
TCGAGCGGCTCACCGCCGACGGGCGGGCCCTGACCGAGGCCGACGTGGCCCGGCTGTTCAAGGCCTATGTCGCGCCGGTC
GGGCTCGAGACCTCCGAGCGGGTGGCCGAGAACGCCCGCCGCATCCTGCGCAGCATGGAGCAGGATGCGCTGGAGGCGAC
CGACCGCACCTCGGCCTTCGACCAGTCGCTGTCGCAGTGGCAGGCCGAGCTCGATCGCGAGGCGAACGGTGGCGCGGTGC
TGCAGGGCGTGGTGGACAGCACGCGCGAGATGTCGGAAGCGATGCGCCAGCTGCAGAGCCGGCTGGACGTGAACCAGCGC
GAGATCGCGCAGCTACGGGCCGAGGTGGCTGCCGCCCGCAGCGAGGCACAGACCGACAGCCTGACCGGCCTGCACAACCG
CCGCTCCTTCGAGCAGCACATCGCCAAGTTCCTGGCCGACCGCGAGGCGGCGATGTCGCTGGTGCTGGTCGACATCGACC
ACTTCAAGCTGGTCAACGACACCCACGGCCATCTGTTCGGTGACCAGGTGCTGATGGCGGTGGCGCGGGTGCTGAAGGAG
AGCGTGCGCAACGACGACCTGGCCGCCCGCATCGGCGGCGAGGAGTTCGCACTGCTGCTGCCGTCGACGCCGCTCAAGGG
CGCGGTCGAGCTGGCCGAGCGCATCCGCACCTCGATCGCCAACAGCCGCATCCGCCGCCGCAACAGCGAGCAGCAGGTCG
GGCAGATCACGGTGTCGCTCGGCGTCGCCGACCTGTGGCCCAGCGACAACGGCGAGAGCTGGTTCTCGCGTGCCGACGAG
GCGCTCTACGCCTCCAAGCGCGAGGGTCGCAATCGCGTCACGGCGCCGTCGCTGCTGTCACGGCATGCCGTGACCGGCGG
CGTCAACCGGTCCTAG

Upstream 100 bases:

>100_bases
GACCCCTGACCGCTGCGGCGGCCGTCCTGGTGCAGCGCGTGGCGCGCCGGGTGGCGAGGCGGACGTCGGCACGGCAGCAA
CTAGACAACAAGAGCTTGCA

Downstream 100 bases:

>100_bases
AGAAAGCGCTCCAGCAGCTTCTTCGAGCGCCGGTCCAGCGCCAGGCGGTCGCGCACCAGGAACTGGATGCCGTGGCTGTC
GACGATCAGCAGCGCGCCGT

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MISGNYPDSVERSSELLRLALPQMAKHSVALHPINYAVWYEYVSGRSSDLKAEIERLTADGRALTEADVARLFKAYVAPV
GLETSERVAENARRILRSMEQDALEATDRTSAFDQSLSQWQAELDREANGGAVLQGVVDSTREMSEAMRQLQSRLDVNQR
EIAQLRAEVAAARSEAQTDSLTGLHNRRSFEQHIAKFLADREAAMSLVLVDIDHFKLVNDTHGHLFGDQVLMAVARVLKE
SVRNDDLAARIGGEEFALLLPSTPLKGAVELAERIRTSIANSRIRRRNSEQQVGQITVSLGVADLWPSDNGESWFSRADE
ALYASKREGRNRVTAPSLLSRHAVTGGVNRS

Sequences:

>Translated_351_residues
MISGNYPDSVERSSELLRLALPQMAKHSVALHPINYAVWYEYVSGRSSDLKAEIERLTADGRALTEADVARLFKAYVAPV
GLETSERVAENARRILRSMEQDALEATDRTSAFDQSLSQWQAELDREANGGAVLQGVVDSTREMSEAMRQLQSRLDVNQR
EIAQLRAEVAAARSEAQTDSLTGLHNRRSFEQHIAKFLADREAAMSLVLVDIDHFKLVNDTHGHLFGDQVLMAVARVLKE
SVRNDDLAARIGGEEFALLLPSTPLKGAVELAERIRTSIANSRIRRRNSEQQVGQITVSLGVADLWPSDNGESWFSRADE
ALYASKREGRNRVTAPSLLSRHAVTGGVNRS
>Mature_351_residues
MISGNYPDSVERSSELLRLALPQMAKHSVALHPINYAVWYEYVSGRSSDLKAEIERLTADGRALTEADVARLFKAYVAPV
GLETSERVAENARRILRSMEQDALEATDRTSAFDQSLSQWQAELDREANGGAVLQGVVDSTREMSEAMRQLQSRLDVNQR
EIAQLRAEVAAARSEAQTDSLTGLHNRRSFEQHIAKFLADREAAMSLVLVDIDHFKLVNDTHGHLFGDQVLMAVARVLKE
SVRNDDLAARIGGEEFALLLPSTPLKGAVELAERIRTSIANSRIRRRNSEQQVGQITVSLGVADLWPSDNGESWFSRADE
ALYASKREGRNRVTAPSLLSRHAVTGGVNRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=164, Percent_Identity=45.7317073170732, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787262, Length=199, Percent_Identity=35.1758793969849, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI87082007, Length=186, Percent_Identity=37.0967741935484, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786584, Length=160, Percent_Identity=36.25, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=36.3095238095238, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1787802, Length=199, Percent_Identity=32.1608040201005, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=37.7358490566038, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788381, Length=166, Percent_Identity=36.7469879518072, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081974, Length=162, Percent_Identity=30.2469135802469, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788085, Length=195, Percent_Identity=31.2820512820513, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787056, Length=170, Percent_Identity=32.9411764705882, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787541, Length=167, Percent_Identity=35.3293413173653, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081977, Length=190, Percent_Identity=31.5789473684211, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788956, Length=180, Percent_Identity=31.6666666666667, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 38890; Mature: 38890

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGNYPDSVERSSELLRLALPQMAKHSVALHPINYAVWYEYVSGRSSDLKAEIERLTAD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHCC
GRALTEADVARLFKAYVAPVGLETSERVAENARRILRSMEQDALEATDRTSAFDQSLSQW
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAELDREANGGAVLQGVVDSTREMSEAMRQLQSRLDVNQREIAQLRAEVAAARSEAQTDS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LTGLHNRRSFEQHIAKFLADREAAMSLVLVDIDHFKLVNDTHGHLFGDQVLMAVARVLKE
HHHHHHHHHHHHHHHHHHHHHHHHHEEHEEECHHHEEECCCCCCHHHHHHHHHHHHHHHH
SVRNDDLAARIGGEEFALLLPSTPLKGAVELAERIRTSIANSRIRRRNSEQQVGQITVSL
HHCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEE
GVADLWPSDNGESWFSRADEALYASKREGRNRVTAPSLLSRHAVTGGVNRS
CHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MISGNYPDSVERSSELLRLALPQMAKHSVALHPINYAVWYEYVSGRSSDLKAEIERLTAD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHCC
GRALTEADVARLFKAYVAPVGLETSERVAENARRILRSMEQDALEATDRTSAFDQSLSQW
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAELDREANGGAVLQGVVDSTREMSEAMRQLQSRLDVNQREIAQLRAEVAAARSEAQTDS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LTGLHNRRSFEQHIAKFLADREAAMSLVLVDIDHFKLVNDTHGHLFGDQVLMAVARVLKE
HHHHHHHHHHHHHHHHHHHHHHHHHEEHEEECHHHEEECCCCCCHHHHHHHHHHHHHHHH
SVRNDDLAARIGGEEFALLLPSTPLKGAVELAERIRTSIANSRIRRRNSEQQVGQITVSL
HHCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEE
GVADLWPSDNGESWFSRADEALYASKREGRNRVTAPSLLSRHAVTGGVNRS
CHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]