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The map label for this gene is cphA [H]

Identifier: 124266215

GI number: 124266215

Start: 1089337

End: 1091604

Strand: Direct

Name: cphA [H]

Synonym: Mpe_A1022

Alternate gene names: 124266215

Gene position: 1089337-1091604 (Clockwise)

Preceding gene: 124266212

Following gene: 124266216

Centisome position: 26.94

GC content: 71.96

Gene sequence:

>2268_bases
GTGCCGCATGGAATGCGGCCCGGAGCGTGGTGCCAAGGAGCCGGTCGGGCGCACAATCGTGCGTCGGTCCTGGGCTGCCC
GGGCGCCTCGTCCCCGCCGAAAATGAGCAAGAAAAACGACCTGCAACTGCTCCGCATCAATTACCTGCGCGGCCCCAACA
TCTGGACCTACCGTCCGGTGCTGGAAACCTGGCTCGACCTCGGCGAGCTCGAAGACCACCCCTCCCATCTGTTGCCCGGC
TTCAACGAGCGCCTGTGCGCGCTGCTGCCGGCGCTCGAGGAGCACCACTGCGGCGTGGGCGAGCGGGGCGGGTTCCTGCA
GCGCCTGCGGGAGGGCACCTGGTGCGGCCACGTGCTGGAGCACGTGGTCATCGAGCTCCTCAACCTGGCGGGCATGCCCA
CCGGTTTCGGCCAGACTCGCAGCACGTCGCAGCGGGGTGTCTACCGGATGGTGTTTCGCGCCCGCGAGGAGCAGGTCGCG
CGCGCGGCGCTGGCCGAAGGCCACCGGCTGCTGATGGCCGCCATCAACGATGAGGCCTTCGATGTCGCTGCGGCCGTGGC
CCGCGTGCGCGAGCAGGTCGACGACACCTATTTCGGGCCCAGCACCGCCGCCATCGTCGGCGCCGCCACCGAACGTGGCA
TCCCGCACATCCGCCTCAATGACGGCAACCTGGTGCAGCTCGGCCACGGTGCCCGCCAGCGCCGCATCTGGACCGCCGAG
ACCGACCGCACCAGCGCCATCGCCGAGGGCATCGCCGGCGACAAGGACCTGACCAAGCGTCTGCTCAAGTCCTGCGGCGT
GCCGGTGCCGGAGGGTGAGGTCGTCGACAGCGTCGAGGCCGCCTGGGAGGCGGCGCAGGACATCGGCCTGCCGGTGGCAC
TGAAGCCGACCGACGGCAACCACGGCCGCGGCGTCACGCTGGACCTGACCAGCCGCGAGGACATCGAGGCCGCGTATGCC
TATGCCGACCTGCACGGCAGCGAGGTCATGGTCGAGCGCCACGTGCCCGGCCAGGAGCACCGCCTGCTGGTGGTGGGCGG
CCGGGTGGTGGCCGCAGCGCGCGGCGAGACCGCCTGGGTCACCGGTGACGGCCGTTCCACGGTGAGTGAGCTGGTCGACG
CCCAGATCAACACCGACCCGAGGCGCGGCGAGACCGAGGACTTCCCGCTCGGCCTGATCGAGACCGACAAGGACGGCGCG
GTGCTGTCCGACCTGCAGCGCCAGGGGCTCGCGCCCGATGCGGTGCCGGCCAGCGGCCGCCGCGTGCTGATCCAGCGCAA
CGGCAACGTCGCGATCGACTGCAGCGACCAGGTCCACCCCGAGGTCGACCACATCGTGTCGCTCGCCGCGCGCGTGGTGG
GCCTGGACATCGCCGGCGTCGACGTCGTGGCCGAGGACATCTCGCGCCCGCTGGCCGAGCAGGGCGGCGCGATCGTCGAG
GTCAACGCCGGCCCCGGGCTGCTGATGCACCTGCGGCCGGCCGAGGGCATGCCGCGGCCGGTCGGCCAAGCCATCATCGA
CCACCTGTTCGCCGAAACGGAAAGCGGGCGCATTCCCATCGTCGGCGTGGCCGGGACCCGAGGCACCCACACCATCGCCC
GGCTGGTGGCCTGGCTGGTGCACCTGAGCGGCCGCCACGTCGGGCTGGCCTGCCGCGACGGCCTGTTCCTCGGCGGACGC
CGGATCGAGCACGGCGACTGCGCGCACTGGGAAGCCAGCCACCGGCTGCTGATCAACCGGCAGGTGGAGGTGGCGGTGGT
GGAGAACGGCGCCGAGGCCATCCTGCGCGACGGCCTCGCCTACGACCGCTGCCAGGTCGGCGTCGTCACCGACCTCGACG
GCGCCGCGGCGCTGACGGCGTTCGACATTCGCGAATCCGACCAGATGCTCAAGGTGCTGCGCACCCAGGTCGACGTGGTA
CTGCCGGACGGCGTGGCGGTGCTCAATGCCGACGACGAGCGGGTGGCCGAACTGGCCGGCCTGTGCGACGGCGAGGTGAT
CCTCTACGGCGTCGACGCAGCCACACCGGTCCTGCAGGCGCAGCGCGCCCAGGGCGGGCGAGCCGTGTTCCTGCGCCACG
GCCGCGCGATCCTGGCCACCGGCGGGGTCGAGACGCAGGGACCCGAATTCACCCGTGGCCGCATGGCCGAGGTGCCGCCG
GAGACCATGCTGGCGGCCATCGCCGCCGCCTGGGCGCTGGGGATCGCGCCCGAACTGGCGGCCGCCGGCATCGAGACCTT
CCAGCTCGAACCGAAGACCACGCACTGA

Upstream 100 bases:

>100_bases
ACTGGATGGTGATGATGCATTCTGATTTGTTCTCGAAGACCCACAAGGCGGCCCTCAATCCCTCGGAAGGGCCCGAGATT
CTGACCGATGCCGGGTTGGC

Downstream 100 bases:

>100_bases
GCCCCGCCGGGGCCCCGACAATCGACGCGAACGGCGATCTGCCCGAACCACCCGAAGAGCAGCAGCGATGGAAGTTTCCC
GCATCCGTGCCTTGCGCGGC

Product: cyanophycin synthetase

Products: NA

Alternate protein names: Cyanophycin synthase [H]

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MPHGMRPGAWCQGAGRAHNRASVLGCPGASSPPKMSKKNDLQLLRINYLRGPNIWTYRPVLETWLDLGELEDHPSHLLPG
FNERLCALLPALEEHHCGVGERGGFLQRLREGTWCGHVLEHVVIELLNLAGMPTGFGQTRSTSQRGVYRMVFRAREEQVA
RAALAEGHRLLMAAINDEAFDVAAAVARVREQVDDTYFGPSTAAIVGAATERGIPHIRLNDGNLVQLGHGARQRRIWTAE
TDRTSAIAEGIAGDKDLTKRLLKSCGVPVPEGEVVDSVEAAWEAAQDIGLPVALKPTDGNHGRGVTLDLTSREDIEAAYA
YADLHGSEVMVERHVPGQEHRLLVVGGRVVAAARGETAWVTGDGRSTVSELVDAQINTDPRRGETEDFPLGLIETDKDGA
VLSDLQRQGLAPDAVPASGRRVLIQRNGNVAIDCSDQVHPEVDHIVSLAARVVGLDIAGVDVVAEDISRPLAEQGGAIVE
VNAGPGLLMHLRPAEGMPRPVGQAIIDHLFAETESGRIPIVGVAGTRGTHTIARLVAWLVHLSGRHVGLACRDGLFLGGR
RIEHGDCAHWEASHRLLINRQVEVAVVENGAEAILRDGLAYDRCQVGVVTDLDGAAALTAFDIRESDQMLKVLRTQVDVV
LPDGVAVLNADDERVAELAGLCDGEVILYGVDAATPVLQAQRAQGGRAVFLRHGRAILATGGVETQGPEFTRGRMAEVPP
ETMLAAIAAAWALGIAPELAAAGIETFQLEPKTTH

Sequences:

>Translated_755_residues
MPHGMRPGAWCQGAGRAHNRASVLGCPGASSPPKMSKKNDLQLLRINYLRGPNIWTYRPVLETWLDLGELEDHPSHLLPG
FNERLCALLPALEEHHCGVGERGGFLQRLREGTWCGHVLEHVVIELLNLAGMPTGFGQTRSTSQRGVYRMVFRAREEQVA
RAALAEGHRLLMAAINDEAFDVAAAVARVREQVDDTYFGPSTAAIVGAATERGIPHIRLNDGNLVQLGHGARQRRIWTAE
TDRTSAIAEGIAGDKDLTKRLLKSCGVPVPEGEVVDSVEAAWEAAQDIGLPVALKPTDGNHGRGVTLDLTSREDIEAAYA
YADLHGSEVMVERHVPGQEHRLLVVGGRVVAAARGETAWVTGDGRSTVSELVDAQINTDPRRGETEDFPLGLIETDKDGA
VLSDLQRQGLAPDAVPASGRRVLIQRNGNVAIDCSDQVHPEVDHIVSLAARVVGLDIAGVDVVAEDISRPLAEQGGAIVE
VNAGPGLLMHLRPAEGMPRPVGQAIIDHLFAETESGRIPIVGVAGTRGTHTIARLVAWLVHLSGRHVGLACRDGLFLGGR
RIEHGDCAHWEASHRLLINRQVEVAVVENGAEAILRDGLAYDRCQVGVVTDLDGAAALTAFDIRESDQMLKVLRTQVDVV
LPDGVAVLNADDERVAELAGLCDGEVILYGVDAATPVLQAQRAQGGRAVFLRHGRAILATGGVETQGPEFTRGRMAEVPP
ETMLAAIAAAWALGIAPELAAAGIETFQLEPKTTH
>Mature_754_residues
PHGMRPGAWCQGAGRAHNRASVLGCPGASSPPKMSKKNDLQLLRINYLRGPNIWTYRPVLETWLDLGELEDHPSHLLPGF
NERLCALLPALEEHHCGVGERGGFLQRLREGTWCGHVLEHVVIELLNLAGMPTGFGQTRSTSQRGVYRMVFRAREEQVAR
AALAEGHRLLMAAINDEAFDVAAAVARVREQVDDTYFGPSTAAIVGAATERGIPHIRLNDGNLVQLGHGARQRRIWTAET
DRTSAIAEGIAGDKDLTKRLLKSCGVPVPEGEVVDSVEAAWEAAQDIGLPVALKPTDGNHGRGVTLDLTSREDIEAAYAY
ADLHGSEVMVERHVPGQEHRLLVVGGRVVAAARGETAWVTGDGRSTVSELVDAQINTDPRRGETEDFPLGLIETDKDGAV
LSDLQRQGLAPDAVPASGRRVLIQRNGNVAIDCSDQVHPEVDHIVSLAARVVGLDIAGVDVVAEDISRPLAEQGGAIVEV
NAGPGLLMHLRPAEGMPRPVGQAIIDHLFAETESGRIPIVGVAGTRGTHTIARLVAWLVHLSGRHVGLACRDGLFLGGRR
IEHGDCAHWEASHRLLINRQVEVAVVENGAEAILRDGLAYDRCQVGVVTDLDGAAALTAFDIRESDQMLKVLRTQVDVVL
PDGVAVLNADDERVAELAGLCDGEVILYGVDAATPVLQAQRAQGGRAVFLRHGRAILATGGVETQGPEFTRGRMAEVPPE
TMLAAIAAAWALGIAPELAAAGIETFQLEPKTTH

Specific function: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011810
- InterPro:   IPR004101
- InterPro:   IPR013221 [H]

Pfam domain/function: PF02875 Mur_ligase_C; PF08245 Mur_ligase_M; PF08443 RimK [H]

EC number: =6.3.2.29; =6.3.2.30 [H]

Molecular weight: Translated: 80813; Mature: 80682

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHGMRPGAWCQGAGRAHNRASVLGCPGASSPPKMSKKNDLQLLRINYLRGPNIWTYRPV
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEHHH
LETWLDLGELEDHPSHLLPGFNERLCALLPALEEHHCGVGERGGFLQRLREGTWCGHVLE
HHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHH
HVVIELLNLAGMPTGFGQTRSTSQRGVYRMVFRAREEQVARAALAEGHRLLMAAINDEAF
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHH
DVAAAVARVREQVDDTYFGPSTAAIVGAATERGIPHIRLNDGNLVQLGHGARQRRIWTAE
HHHHHHHHHHHHHCCCCCCCCHHHEEECHHHCCCCEEEECCCCEEEECCCCCCCEEEECC
TDRTSAIAEGIAGDKDLTKRLLKSCGVPVPEGEVVDSVEAAWEAAQDIGLPVALKPTDGN
CCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
HGRGVTLDLTSREDIEAAYAYADLHGSEVMVERHVPGQEHRLLVVGGRVVAAARGETAWV
CCCEEEEEECCCCCHHHHHEEEECCCCEEEEEECCCCCCCEEEEECCEEEEEECCCEEEE
TGDGRSTVSELVDAQINTDPRRGETEDFPLGLIETDKDGAVLSDLQRQGLAPDAVPASGR
ECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCC
RVLIQRNGNVAIDCSDQVHPEVDHIVSLAARVVGLDIAGVDVVAEDISRPLAEQGGAIVE
EEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEE
VNAGPGLLMHLRPAEGMPRPVGQAIIDHLFAETESGRIPIVGVAGTRGTHTIARLVAWLV
EECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
HLSGRHVGLACRDGLFLGGRRIEHGDCAHWEASHRLLINRQVEVAVVENGAEAILRDGLA
HHCCCEEEEEECCCEEECCEEECCCCCCCCCCCCEEEEECCEEEEEECCCHHHHHHCCCC
YDRCQVGVVTDLDGAAALTAFDIRESDQMLKVLRTQVDVVLPDGVAVLNADDERVAELAG
CCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHCEECCCCEEEECCCHHHHHHHHC
LCDGEVILYGVDAATPVLQAQRAQGGRAVFLRHGRAILATGGVETQGPEFTRGRMAEVPP
CCCCCEEEEECCCCCHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCH
ETMLAAIAAAWALGIAPELAAAGIETFQLEPKTTH
HHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure 
PHGMRPGAWCQGAGRAHNRASVLGCPGASSPPKMSKKNDLQLLRINYLRGPNIWTYRPV
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEHHH
LETWLDLGELEDHPSHLLPGFNERLCALLPALEEHHCGVGERGGFLQRLREGTWCGHVLE
HHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHH
HVVIELLNLAGMPTGFGQTRSTSQRGVYRMVFRAREEQVARAALAEGHRLLMAAINDEAF
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHH
DVAAAVARVREQVDDTYFGPSTAAIVGAATERGIPHIRLNDGNLVQLGHGARQRRIWTAE
HHHHHHHHHHHHHCCCCCCCCHHHEEECHHHCCCCEEEECCCCEEEECCCCCCCEEEECC
TDRTSAIAEGIAGDKDLTKRLLKSCGVPVPEGEVVDSVEAAWEAAQDIGLPVALKPTDGN
CCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
HGRGVTLDLTSREDIEAAYAYADLHGSEVMVERHVPGQEHRLLVVGGRVVAAARGETAWV
CCCEEEEEECCCCCHHHHHEEEECCCCEEEEEECCCCCCCEEEEECCEEEEEECCCEEEE
TGDGRSTVSELVDAQINTDPRRGETEDFPLGLIETDKDGAVLSDLQRQGLAPDAVPASGR
ECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCC
RVLIQRNGNVAIDCSDQVHPEVDHIVSLAARVVGLDIAGVDVVAEDISRPLAEQGGAIVE
EEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEE
VNAGPGLLMHLRPAEGMPRPVGQAIIDHLFAETESGRIPIVGVAGTRGTHTIARLVAWLV
EECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
HLSGRHVGLACRDGLFLGGRRIEHGDCAHWEASHRLLINRQVEVAVVENGAEAILRDGLA
HHCCCEEEEEECCCEEECCEEECCCCCCCCCCCCEEEEECCEEEEEECCCHHHHHHCCCC
YDRCQVGVVTDLDGAAALTAFDIRESDQMLKVLRTQVDVVLPDGVAVLNADDERVAELAG
CCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHCEECCCCEEEECCCHHHHHHHHC
LCDGEVILYGVDAATPVLQAQRAQGGRAVFLRHGRAILATGGVETQGPEFTRGRMAEVPP
CCCCCEEEEECCCCCHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCH
ETMLAAIAAAWALGIAPELAAAGIETFQLEPKTTH
HHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9652408 [H]