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The map label for this gene is glcD [H]

Identifier: 124266152

GI number: 124266152

Start: 1016627

End: 1018132

Strand: Direct

Name: glcD [H]

Synonym: Mpe_A0959

Alternate gene names: 124266152

Gene position: 1016627-1018132 (Clockwise)

Preceding gene: 124266151

Following gene: 124266153

Centisome position: 25.14

GC content: 70.45

Gene sequence:

>1506_bases
ATGTCCGGATCCCCTTCGAGCCGGGCGGCTGCCGCCTCGGCCTCCCCTGCTGCGCTCCAGACGCGGGTCGTCGAGGCCCT
GAGTGCCGTGCTGCCGCGCCACGCCATCCTGTTCCGCAAGGAAGAGACGGGACCGTTCGAATGCGACGGTCTGACCGCCT
ATCGCGCGCAGCCGCTGGTCGTGGTGCTGCCCGAAACCGAGTCGCAGGTGGCCGACGTGCTGCGCACCTGCCATGCGCTG
GGTGTGCCCGTGGTGTCGCGCGGGGCGGGCACCGGGCTGTCCGGCGGGGCGCTGCCGCACGAGCGCGGCGTGACGCTGTC
GCTGGCGCGCCTGAACCGCATCGTGTCCGTCGATCGGATCGCCTGCACGGCCACGGTCCAGTGCGGCGTGCGCAATGCGG
CGATCAGCGAGGCCGCGGCGCCGCACGGTCTCTACTACGCGCCGGACCCCAGCAGCCAGATCGCCTGCACCATCGGCGGC
AACGTGGCCGAGAACGCCGGTGGCGTGCATTGCCTCAAGTACGGGCTCACGCTGCACAACGTGCTGCGCGTGCGGGGCTA
TCTCGCCGACGGCGAGCCGGTCGAGTTCGGCTCCGAGGCGCTCGACGCGCCCGGCCTGGACCTGCTGTCGGCGGTGATCG
GCTCCGAGGGCATGCTGGCGGTGACGCTCGAGGTCACCGTGAAGCTGGTGCCCAAGCCGCTGCTGGCGCGCGCCATCCTG
GCCAGCTTCGACGACGTGCGCAAGGCCGGCAACGCGGTGGCCGCGCTGATCGGCGCCGGCATCATCCCGGCCGGCCTGGA
GATGATGGACAAGCCGATGACCGCCGCCGTCGAGGACTTCGTGCACGCCGGCTACGACCTCGACGCCCACGCCATCCTCA
TCTGCGAGAGCGACGGCACGCCCGAGGAGGTGGAGGAGGAGATCGCCCGCATGGTGGCGGTGATGGAAGGGGCCGGCGCG
ACACGCTTCGACATCAGCACCAGCGAGGCCGAGCGCCTGAAGTTCTGGAGCGGGCGCATGAACGCGTTCCCGGCCAGCGG
GCGTATCAGCCCCGACTACCTCTGCATGGACTCGACCATCCCGCGCCGCAAGCTGGCCGAGATGCTGGGCCGCATCGGCG
AGATGTCGGTGAGCTACGGCCTGCGCTGCTGCAACGTGTTCCATGCCGGCGACGGCAACCTGCACCCGATGATCCTGTTC
GACGCCAACGACCCCGACCAGTTGCAGCGCGCCGAGCGCTTCGGCGCGGAGATCCTGGAGACCAGCGTCGAGATGGGCGG
CAGCATCACCGGCGAGCACGGCGTGGGCGTCGAGAAACTCAACTCGATGTGCGTGCAGTTCACGCAGGAGGAACGCGAGC
AGATGCTGCGCCTGAAGGAGGCCTTCGACCCGCGCTCGCTGCTCAATCCCGGCAAGGCCATCCCGACGCTGAACCGCTGT
GCCGAGTACGGCCGCATGACGGTGAGGGGCGGGCGCCTGCCGTTCGCGGACCTGCCGCGCTTCTGA

Upstream 100 bases:

>100_bases
CTACATCGATTCGGCGAGCACCTGCAGCGACGACCTGCTGCTGCCGTGGAAGACGCTGCTCGACATCGCGCGGCGCACCT
CCTTCGACGGCTGATTCGCG

Downstream 100 bases:

>100_bases
CGATGGAACCGCTCTCGCCCTCCGACGCGACCGAACTCCGCCTGGTCGAGCAGGTGCTCGAGGCTCGCAACGAAGGCCGA
CGCCTCGAGATCCGCGGCGG

Product: putative glycolate oxidase (FAD-linked subunit) oxidoreductase protein

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MSGSPSSRAAAASASPAALQTRVVEALSAVLPRHAILFRKEETGPFECDGLTAYRAQPLVVVLPETESQVADVLRTCHAL
GVPVVSRGAGTGLSGGALPHERGVTLSLARLNRIVSVDRIACTATVQCGVRNAAISEAAAPHGLYYAPDPSSQIACTIGG
NVAENAGGVHCLKYGLTLHNVLRVRGYLADGEPVEFGSEALDAPGLDLLSAVIGSEGMLAVTLEVTVKLVPKPLLARAIL
ASFDDVRKAGNAVAALIGAGIIPAGLEMMDKPMTAAVEDFVHAGYDLDAHAILICESDGTPEEVEEEIARMVAVMEGAGA
TRFDISTSEAERLKFWSGRMNAFPASGRISPDYLCMDSTIPRRKLAEMLGRIGEMSVSYGLRCCNVFHAGDGNLHPMILF
DANDPDQLQRAERFGAEILETSVEMGGSITGEHGVGVEKLNSMCVQFTQEEREQMLRLKEAFDPRSLLNPGKAIPTLNRC
AEYGRMTVRGGRLPFADLPRF

Sequences:

>Translated_501_residues
MSGSPSSRAAAASASPAALQTRVVEALSAVLPRHAILFRKEETGPFECDGLTAYRAQPLVVVLPETESQVADVLRTCHAL
GVPVVSRGAGTGLSGGALPHERGVTLSLARLNRIVSVDRIACTATVQCGVRNAAISEAAAPHGLYYAPDPSSQIACTIGG
NVAENAGGVHCLKYGLTLHNVLRVRGYLADGEPVEFGSEALDAPGLDLLSAVIGSEGMLAVTLEVTVKLVPKPLLARAIL
ASFDDVRKAGNAVAALIGAGIIPAGLEMMDKPMTAAVEDFVHAGYDLDAHAILICESDGTPEEVEEEIARMVAVMEGAGA
TRFDISTSEAERLKFWSGRMNAFPASGRISPDYLCMDSTIPRRKLAEMLGRIGEMSVSYGLRCCNVFHAGDGNLHPMILF
DANDPDQLQRAERFGAEILETSVEMGGSITGEHGVGVEKLNSMCVQFTQEEREQMLRLKEAFDPRSLLNPGKAIPTLNRC
AEYGRMTVRGGRLPFADLPRF
>Mature_500_residues
SGSPSSRAAAASASPAALQTRVVEALSAVLPRHAILFRKEETGPFECDGLTAYRAQPLVVVLPETESQVADVLRTCHALG
VPVVSRGAGTGLSGGALPHERGVTLSLARLNRIVSVDRIACTATVQCGVRNAAISEAAAPHGLYYAPDPSSQIACTIGGN
VAENAGGVHCLKYGLTLHNVLRVRGYLADGEPVEFGSEALDAPGLDLLSAVIGSEGMLAVTLEVTVKLVPKPLLARAILA
SFDDVRKAGNAVAALIGAGIIPAGLEMMDKPMTAAVEDFVHAGYDLDAHAILICESDGTPEEVEEEIARMVAVMEGAGAT
RFDISTSEAERLKFWSGRMNAFPASGRISPDYLCMDSTIPRRKLAEMLGRIGEMSVSYGLRCCNVFHAGDGNLHPMILFD
ANDPDQLQRAERFGAEILETSVEMGGSITGEHGVGVEKLNSMCVQFTQEEREQMLRLKEAFDPRSLLNPGKAIPTLNRCA
EYGRMTVRGGRLPFADLPRF

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=428, Percent_Identity=28.7383177570093, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI37595754, Length=451, Percent_Identity=27.7161862527716, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI119964728, Length=445, Percent_Identity=28.314606741573, Blast_Score=142, Evalue=9e-34,
Organism=Escherichia coli, GI1789351, Length=488, Percent_Identity=59.8360655737705, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1787977, Length=502, Percent_Identity=24.5019920318725, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI48994907, Length=457, Percent_Identity=24.72647702407, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71992373, Length=429, Percent_Identity=26.8065268065268, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI71992381, Length=429, Percent_Identity=25.4079254079254, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71992392, Length=351, Percent_Identity=26.4957264957265, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534361, Length=453, Percent_Identity=26.7108167770419, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17556096, Length=289, Percent_Identity=23.1833910034602, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320027, Length=438, Percent_Identity=25.3424657534247, Blast_Score=157, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6320023, Length=484, Percent_Identity=27.2727272727273, Blast_Score=144, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6320764, Length=457, Percent_Identity=25.382932166302, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI18921117, Length=474, Percent_Identity=28.4810126582279, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24639277, Length=474, Percent_Identity=28.4810126582279, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24639275, Length=474, Percent_Identity=28.4810126582279, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24653753, Length=464, Percent_Identity=23.4913793103448, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.3.15

Molecular weight: Translated: 53195; Mature: 53063

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSPSSRAAAASASPAALQTRVVEALSAVLPRHAILFRKEETGPFECDGLTAYRAQPLV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCEEEECCCCEE
VVLPETESQVADVLRTCHALGVPVVSRGAGTGLSGGALPHERGVTLSLARLNRIVSVDRI
EEECCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
ACTATVQCGVRNAAISEAAAPHGLYYAPDPSSQIACTIGGNVAENAGGVHCLKYGLTLHN
EEEEEHHCCCCHHHHHHHCCCCCEEECCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHH
VLRVRGYLADGEPVEFGSEALDAPGLDLLSAVIGSEGMLAVTLEVTVKLVPKPLLARAIL
HHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHHCCCCEEEEEEEEEEEECCHHHHHHHHH
ASFDDVRKAGNAVAALIGAGIIPAGLEMMDKPMTAAVEDFVHAGYDLDAHAILICESDGT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCC
PEEVEEEIARMVAVMEGAGATRFDISTSEAERLKFWSGRMNAFPASGRISPDYLCMDSTI
HHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCC
PRRKLAEMLGRIGEMSVSYGLRCCNVFHAGDGNLHPMILFDANDPDQLQRAERFGAEILE
CHHHHHHHHHHHHHHHHHHCHHEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
TSVEMGGSITGEHGVGVEKLNSMCVQFTQEEREQMLRLKEAFDPRSLLNPGKAIPTLNRC
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHH
AEYGRMTVRGGRLPFADLPRF
HHHCCEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SGSPSSRAAAASASPAALQTRVVEALSAVLPRHAILFRKEETGPFECDGLTAYRAQPLV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCEEEECCCCEE
VVLPETESQVADVLRTCHALGVPVVSRGAGTGLSGGALPHERGVTLSLARLNRIVSVDRI
EEECCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
ACTATVQCGVRNAAISEAAAPHGLYYAPDPSSQIACTIGGNVAENAGGVHCLKYGLTLHN
EEEEEHHCCCCHHHHHHHCCCCCEEECCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHH
VLRVRGYLADGEPVEFGSEALDAPGLDLLSAVIGSEGMLAVTLEVTVKLVPKPLLARAIL
HHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHHCCCCEEEEEEEEEEEECCHHHHHHHHH
ASFDDVRKAGNAVAALIGAGIIPAGLEMMDKPMTAAVEDFVHAGYDLDAHAILICESDGT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCC
PEEVEEEIARMVAVMEGAGATRFDISTSEAERLKFWSGRMNAFPASGRISPDYLCMDSTI
HHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCC
PRRKLAEMLGRIGEMSVSYGLRCCNVFHAGDGNLHPMILFDANDPDQLQRAERFGAEILE
CHHHHHHHHHHHHHHHHHHCHHEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
TSVEMGGSITGEHGVGVEKLNSMCVQFTQEEREQMLRLKEAFDPRSLLNPGKAIPTLNRC
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHH
AEYGRMTVRGGRLPFADLPRF
HHHCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]