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The map label for this gene is glcE [H]

Identifier: 124266153

GI number: 124266153

Start: 1018135

End: 1019241

Strand: Direct

Name: glcE [H]

Synonym: Mpe_A0960

Alternate gene names: 124266153

Gene position: 1018135-1019241 (Clockwise)

Preceding gene: 124266152

Following gene: 124266154

Centisome position: 25.18

GC content: 73.35

Gene sequence:

>1107_bases
ATGGAACCGCTCTCGCCCTCCGACGCGACCGAACTCCGCCTGGTCGAGCAGGTGCTCGAGGCTCGCAACGAAGGCCGACG
CCTCGAGATCCGCGGCGGCGGCACCAAGCGCTTCTACGGCGGAGCGCCGCACGGCGACCTGCTGGACCTGCGCCCGCTGG
CTGGCGTGCGGAGCTATGAGCCCACCGAGCTGGTCGTCACGGTGCGTGCCGGCGAGCCGCTCGCCAGGCTGGAGGCGCTG
CTGGCCGATCGGGGCCAGCACCTGGCCTTCGAGCCGCCGCGCTTTGCGCCCGGCGGCACCGTGGGTGGCATGGTCGCCGC
CGGCCTGAGCGGGCCCGGCCGGATCGCGGCGGGGGCGCTGCGCGACCACGTGCTCGGCGTGCGTCTGCTGAACGGGCGGG
GCGAATGCCTCTCCTTCGGCGGGCAGATGATCAAGAACGTCGCGGGCTACGACGTGTCGCGGCTGATGGCCGGCTCGCTC
GGTATCCTCGGCGTGCTGCTCGAGGTGTCGCTGAAGGTGCTACCCCGGCCACCGGCCTCGGTGACGATCAGTCTCGATTG
CGCGACGCAGGCCGATGCGCTGAGACGGCTCGCCGCCTGGGCCTCGCAACCGCTGTCGATCGGCGCCACGGCCTGGCACG
ACGGGCACCTGCGGGTCCGTCTCGACGGTGCCGCCGCGGCGGTGCGGGCCGCCCGGGTGGCCCTGGGTGGGGACGAACTT
CACGAGCGGGCTGCCGCTTCGTGGTGGACCTCGGTGCGCGACCAGCTGCATCCGTTCTTCGACCTCGATCCCTCGGCCCA
GCTCCGGGGCGTGCGGCTCTGGCGCCTGTCGGTGCCGCGAGGCGTGCCGCCGCTCGAGCTGTCGGGCGAGACCTTCGTCG
AATGGGGAGGCGCACTGCGCTGGCTCCGGTCGAGGGAGCCGATCGCCTGCGTGCGTCAGGCGGCTGCCCGCGTGGGCGGC
CACGCCACGCTGATGCGTGGTGACGGCCGGGAAGCCGGCCCGTTCTCACCGCTCTCGCCGGCGCTGCTGCAGCTGCACCA
TCGGCTCAAGCAGGCCTTCGATCCGGAGCGGCTGTTCAACCCGGGCCGGCTCCACGAAGGCCTCTGA

Upstream 100 bases:

>100_bases
CCGGCAAGGCCATCCCGACGCTGAACCGCTGTGCCGAGTACGGCCGCATGACGGTGAGGGGCGGGCGCCTGCCGTTCGCG
GACCTGCCGCGCTTCTGACG

Downstream 100 bases:

>100_bases
GACCGTCATGCAAATCCAGTTGAGTCCCGAGTTCCACGGCGATCGCGAAGCCGCCGAAGCCGAAGCCATCCTGCGCAGCT
GCGTGCACTGCGGGTTCTGC

Product: FAD linked oxidase

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MEPLSPSDATELRLVEQVLEARNEGRRLEIRGGGTKRFYGGAPHGDLLDLRPLAGVRSYEPTELVVTVRAGEPLARLEAL
LADRGQHLAFEPPRFAPGGTVGGMVAAGLSGPGRIAAGALRDHVLGVRLLNGRGECLSFGGQMIKNVAGYDVSRLMAGSL
GILGVLLEVSLKVLPRPPASVTISLDCATQADALRRLAAWASQPLSIGATAWHDGHLRVRLDGAAAAVRAARVALGGDEL
HERAAASWWTSVRDQLHPFFDLDPSAQLRGVRLWRLSVPRGVPPLELSGETFVEWGGALRWLRSREPIACVRQAAARVGG
HATLMRGDGREAGPFSPLSPALLQLHHRLKQAFDPERLFNPGRLHEGL

Sequences:

>Translated_368_residues
MEPLSPSDATELRLVEQVLEARNEGRRLEIRGGGTKRFYGGAPHGDLLDLRPLAGVRSYEPTELVVTVRAGEPLARLEAL
LADRGQHLAFEPPRFAPGGTVGGMVAAGLSGPGRIAAGALRDHVLGVRLLNGRGECLSFGGQMIKNVAGYDVSRLMAGSL
GILGVLLEVSLKVLPRPPASVTISLDCATQADALRRLAAWASQPLSIGATAWHDGHLRVRLDGAAAAVRAARVALGGDEL
HERAAASWWTSVRDQLHPFFDLDPSAQLRGVRLWRLSVPRGVPPLELSGETFVEWGGALRWLRSREPIACVRQAAARVGG
HATLMRGDGREAGPFSPLSPALLQLHHRLKQAFDPERLFNPGRLHEGL
>Mature_368_residues
MEPLSPSDATELRLVEQVLEARNEGRRLEIRGGGTKRFYGGAPHGDLLDLRPLAGVRSYEPTELVVTVRAGEPLARLEAL
LADRGQHLAFEPPRFAPGGTVGGMVAAGLSGPGRIAAGALRDHVLGVRLLNGRGECLSFGGQMIKNVAGYDVSRLMAGSL
GILGVLLEVSLKVLPRPPASVTISLDCATQADALRRLAAWASQPLSIGATAWHDGHLRVRLDGAAAAVRAARVALGGDEL
HERAAASWWTSVRDQLHPFFDLDPSAQLRGVRLWRLSVPRGVPPLELSGETFVEWGGALRWLRSREPIACVRQAAARVGG
HATLMRGDGREAGPFSPLSPALLQLHHRLKQAFDPERLFNPGRLHEGL

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI48994914, Length=356, Percent_Identity=45.2247191011236, Blast_Score=287, Evalue=8e-79,
Organism=Saccharomyces cerevisiae, GI6320027, Length=151, Percent_Identity=26.4900662251656, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF01565 FAD_binding_4 [H]

EC number: 1.1.3.15

Molecular weight: Translated: 39479; Mature: 39479

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLSPSDATELRLVEQVLEARNEGRRLEIRGGGTKRFYGGAPHGDLLDLRPLAGVRSYE
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCC
PTELVVTVRAGEPLARLEALLADRGQHLAFEPPRFAPGGTVGGMVAAGLSGPGRIAAGAL
CCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHH
RDHVLGVRLLNGRGECLSFGGQMIKNVAGYDVSRLMAGSLGILGVLLEVSLKVLPRPPAS
HHHHHEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VTISLDCATQADALRRLAAWASQPLSIGATAWHDGHLRVRLDGAAAAVRAARVALGGDEL
EEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEECCHHHHHHHHHHHCCHHHH
HERAAASWWTSVRDQLHPFFDLDPSAQLRGVRLWRLSVPRGVPPLELSGETFVEWGGALR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEECCCHHHHHHHHHH
WLRSREPIACVRQAAARVGGHATLMRGDGREAGPFSPLSPALLQLHHRLKQAFDPERLFN
HHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCC
PGRLHEGL
CCHHCCCC
>Mature Secondary Structure
MEPLSPSDATELRLVEQVLEARNEGRRLEIRGGGTKRFYGGAPHGDLLDLRPLAGVRSYE
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCC
PTELVVTVRAGEPLARLEALLADRGQHLAFEPPRFAPGGTVGGMVAAGLSGPGRIAAGAL
CCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHH
RDHVLGVRLLNGRGECLSFGGQMIKNVAGYDVSRLMAGSLGILGVLLEVSLKVLPRPPAS
HHHHHEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VTISLDCATQADALRRLAAWASQPLSIGATAWHDGHLRVRLDGAAAAVRAARVALGGDEL
EEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEECCHHHHHHHHHHHCCHHHH
HERAAASWWTSVRDQLHPFFDLDPSAQLRGVRLWRLSVPRGVPPLELSGETFVEWGGALR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEECCCHHHHHHHHHH
WLRSREPIACVRQAAARVGGHATLMRGDGREAGPFSPLSPALLQLHHRLKQAFDPERLFN
HHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCC
PGRLHEGL
CCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8606183; 9278503 [H]