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The map label for this gene is yfcG [H]

Identifier: 124266099

GI number: 124266099

Start: 961135

End: 961821

Strand: Direct

Name: yfcG [H]

Synonym: Mpe_A0906

Alternate gene names: 124266099

Gene position: 961135-961821 (Clockwise)

Preceding gene: 124266098

Following gene: 124266104

Centisome position: 23.77

GC content: 66.96

Gene sequence:

>687_bases
ATGATCGATCTCTACACCTCGGCCACGCCCAACGGCTGGAAGGCCAGCATCCTGCTCGAGGAACTGGGGGTGCCGTACAC
GGTGCATCCGCTGTCGCTGCAGAAGCAGGACCAGAAGACGCCGGCCTTCCTGTCCATCAACCCGAACGGTCGCATCCCGG
CGATCGTCGACCGCAGTGCGGGCGACTTCGCGGTGTTCGAGTCCGGCGCGATCCTGATCTACCTCGCGGAGAAGCACGGC
CGCTTCCTGCCTGCCGACGTGAAGGGGCGTTCGCTCGTCATCCAGTGGCTGATGTTCCAGATGGGCGGCATCGGTCCGAT
GCAGGGCCAGGCGAACGTCTTCCACCGCTACGCGCCCGAGAAGATCCCCTATGCCATCGAGCGCTACCAGAGCGAGACCA
AGCGTCTCTACCGTGTGCTCGACGGTCGGCTGGCCGACCACGAGTTCCTGGCCGGTGACTACTCCATCGCCGACATCGCC
AACTGGTCCTGGGTGTCGCTGTACGACTGGGCCGGCGTGAGCATCGACGATCTGCCGCACCTGCGGCGCTGGCTGGACAC
CATCGCGGCGCGGCCTGCGGTGCAGCGCGGCATCGTCATTCCCGAGCCGCTGCAGCTCGGCGGCGGCGGCGAGGCGGTGA
AGAAGATGGCGCAGTCCATCCTCGTCTCCGCCCCGGGCACGGCCTGA

Upstream 100 bases:

>100_bases
CTCACGGACGACGATCTCGTGGCACTCCAGCACTACGTGCGCAGTCAGGCTATCGTGACTTCACAGCCGACCCCGCCCTA
GTCGGCACGGAGCGCACTGC

Downstream 100 bases:

>100_bases
AGCGACGCCCCCGCTGCTCCAGGCAACTTGCTTCTCGCGCGCGCGCTTCAGCCGCGCATGCCGATCTCCTGCCAGCCCGG
CGACAGCGAGGCGGTGGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MIDLYTSATPNGWKASILLEELGVPYTVHPLSLQKQDQKTPAFLSINPNGRIPAIVDRSAGDFAVFESGAILIYLAEKHG
RFLPADVKGRSLVIQWLMFQMGGIGPMQGQANVFHRYAPEKIPYAIERYQSETKRLYRVLDGRLADHEFLAGDYSIADIA
NWSWVSLYDWAGVSIDDLPHLRRWLDTIAARPAVQRGIVIPEPLQLGGGGEAVKKMAQSILVSAPGTA

Sequences:

>Translated_228_residues
MIDLYTSATPNGWKASILLEELGVPYTVHPLSLQKQDQKTPAFLSINPNGRIPAIVDRSAGDFAVFESGAILIYLAEKHG
RFLPADVKGRSLVIQWLMFQMGGIGPMQGQANVFHRYAPEKIPYAIERYQSETKRLYRVLDGRLADHEFLAGDYSIADIA
NWSWVSLYDWAGVSIDDLPHLRRWLDTIAARPAVQRGIVIPEPLQLGGGGEAVKKMAQSILVSAPGTA
>Mature_228_residues
MIDLYTSATPNGWKASILLEELGVPYTVHPLSLQKQDQKTPAFLSINPNGRIPAIVDRSAGDFAVFESGAILIYLAEKHG
RFLPADVKGRSLVIQWLMFQMGGIGPMQGQANVFHRYAPEKIPYAIERYQSETKRLYRVLDGRLADHEFLAGDYSIADIA
NWSWVSLYDWAGVSIDDLPHLRRWLDTIAARPAVQRGIVIPEPLQLGGGGEAVKKMAQSILVSAPGTA

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=204, Percent_Identity=47.5490196078431, Blast_Score=186, Evalue=9e-49,
Organism=Escherichia coli, GI87082195, Length=214, Percent_Identity=41.588785046729, Blast_Score=154, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6324100, Length=231, Percent_Identity=30.7359307359307, Blast_Score=117, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28571670, Length=171, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45549270, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI85725204, Length=192, Percent_Identity=30.7291666666667, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17737923, Length=192, Percent_Identity=30.7291666666667, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24646249, Length=174, Percent_Identity=32.7586206896552, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17864598, Length=197, Percent_Identity=29.4416243654822, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17864592, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17864594, Length=192, Percent_Identity=30.2083333333333, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17933730, Length=191, Percent_Identity=28.7958115183246, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922932, Length=209, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 25185; Mature: 25185

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYTSATPNGWKASILLEELGVPYTVHPLSLQKQDQKTPAFLSINPNGRIPAIVDRSA
CEEEECCCCCCCCCCEEEHHHHCCCEEECCCCCCCCCCCCCEEEEECCCCCCCEEEECCC
GDFAVFESGAILIYLAEKHGRFLPADVKGRSLVIQWLMFQMGGIGPMQGQANVFHRYAPE
CCEEEEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
KIPYAIERYQSETKRLYRVLDGRLADHEFLAGDYSIADIANWSWVSLYDWAGVSIDDLPH
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHCCCCCEEEEECCCCCCHHHHHH
LRRWLDTIAARPAVQRGIVIPEPLQLGGGGEAVKKMAQSILVSAPGTA
HHHHHHHHHCCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIDLYTSATPNGWKASILLEELGVPYTVHPLSLQKQDQKTPAFLSINPNGRIPAIVDRSA
CEEEECCCCCCCCCCEEEHHHHCCCEEECCCCCCCCCCCCCEEEEECCCCCCCEEEECCC
GDFAVFESGAILIYLAEKHGRFLPADVKGRSLVIQWLMFQMGGIGPMQGQANVFHRYAPE
CCEEEEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
KIPYAIERYQSETKRLYRVLDGRLADHEFLAGDYSIADIANWSWVSLYDWAGVSIDDLPH
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHCCCCCEEEEECCCCCCHHHHHH
LRRWLDTIAARPAVQRGIVIPEPLQLGGGGEAVKKMAQSILVSAPGTA
HHHHHHHHHCCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]