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The map label for this gene is adh [H]

Identifier: 124266070

GI number: 124266070

Start: 917420

End: 919582

Strand: Reverse

Name: adh [H]

Synonym: Mpe_A0877

Alternate gene names: 124266070

Gene position: 919582-917420 (Counterclockwise)

Preceding gene: 124266072

Following gene: 124266068

Centisome position: 22.74

GC content: 70.32

Gene sequence:

>2163_bases
ATGCACTCATGGAAGGCCGTCCTGCGCCATGGCGCGACCCCTCTGATCCTCGCGGCGACCCTGGCCGGCAGTCCCTGCGC
GTCGGCCACGCCGGCGACCCCCGTGAACGCCGCGCGACTGGCCGCCGCGGCCCAGGAGCCCGCCAACTGGATGACGCACG
GCGGCACCTACCAGGAGGCGCGCTACAGCCCGCTGGACCAGATCAACACGCGCAGCATCGCGCGGCTGAAGCTGGCCTGG
TACGGCGACTTCGACACCTCGCGAGGCCAGGAGTCCACGCCCTTGGTGATCGACGGCGTGATGTACACGACCTCGAGCTG
GTCGAAGGTCTACGCCTACGACGCCGCCACCGGCAAGCTGCTGTGGCGCCATGACCCGAAGGTGCCTGGCGACCGCGGCG
CGGACGCCTGCTGCGACGTGGTCAACCGTGGCGTCGCCGCGTGGAACGGCAAGGTCTACGTCGGCACCCTGGACGGCCGG
CTCGAGGCGCTGGACGCGAAGACGGGCAAGCTCGTGTGGTCCACCGTCACGGTGGACCAGACCCGGCCGTACACGATCAC
CGGCGCGCCCCGGGTGGTCAAGGGCAAGGTCCTGATCGGCAACGGCGGCGCGGAGTACGGCGTGCGCGGCTACGTCAGCG
CCTACGACGCCGAGACCGGCGCGCTGGCCTGGCGCTTCTACATGACGCCGAATCCCGAGAACAAGCCCGACGGCGCGGCC
TCGGACGCGATCCTGATGAGCAAGGCCTACGGCACGTGGCACGACGGGGCCTGGAAGCAGACCGGCGGTGGCGGCACGCC
GTGGGATGCCATCGTCTACGACACCGACTTCGATCAGGTGATCATCGGCACCGGCAACGGCAACCCCTGGAGCTGGGAGC
ACCGCTCGGGCAGCAAGGGCGACAACCTGTTCCTGGGTTCGCTCCTCGCACTGGATGCGGAGACGGGCGCCTACAAGTGG
CACTACCAGGAGACCCCGAGCGAGAACTGGGACTTCACCTCCACGCAGCCGATCATCCTGACCGAGCTGACGCTGCAGGG
CCGCCAGCGCAAGGCGCTGCTCCATGCGCCGAAGAACGGCTTCTTCTACGTGGTAGACCGCAAGGACGGCGCGCTGATCT
CGGCCGAGCCCTTCACCACGGTCAACTGGGCGACCGGCATCGACCTGAAGACCGGCCGCCCGATCGAGGCGCCCGGCGCC
CGCTACGAGCGCACGAAGAAGTCGTTCTGGGCCATGCCGGGGCCGTTCGGCTCCCACAACTGGCACCCCATGGCCTTCAG
CCCGAAGACCGGCCTCACCTATATCCCGGTGCAGGACGTGCCGCTCGACTACAACTACTCGCCCGACTTCAAGTACTCGC
CGCAGCGCGGCACCTGGAACACCGGCATCGAGGCCACCACCTTCGCCGGCCCCGGCAGCGAGTCGCATCGGCGCCTGCTG
GCCATGCAGACGCGCGGCGCGCTGGTGGCCTGGGACGCCGTCCGGCAGAAGGAGGCCTGGCGGGTCCAGCACGGCAACCT
GGCGTCGGCGGGCGTGCTGGCGACCGGCGGCAACCTGGTGTTCCAGGGCACGCCCGATGGCCGGCTGGTGGCCTACACGG
CCGACACCGGCCGGCAGGTATGGAGCTGGCAGGGCTTCGACGGCATCATCGCCGGCGCCATGACGTATGCGGTCGGGGGC
GAGCAGTATGTCGCGGTCGTGGCCGGCTTCGGTGGCTCGAACGCCCTGCACGCGCCGTTCGCCGTCGCGCCCAAGGTCGG
TCTGCACGGACGGATCCTGGCCTTCAAGCTCGATGGCCGGGCGGTGCTGCCCGACAACACCAGACCGCTCCTGCCTCCCA
ATGTGCCCGAGCAGACGTGGCCGGCCGAGACCGTGTCGCGCGGCGCCGCACTGTACGGACACTGCGCGGCCTGCCACGGC
TTCGGCACCTACGCCGCCAACGTGATCCCCGATCTGCGCCGCTCGCCGATGCTGTCGGTCAAGTCCGCCTGGGATGCGGT
GGTCCTGGGCGGCGCGCTGGCCGACAAGGGCATGCCGAACTGGACGGGACGCATCGCCGCCGAGGACGTCGAGGCGATCC
GGGCCTATGTGGTCGATCGCGCGCGTCAGCTGAGAGACGACGAGGCGGCCGCGCAGGCCGCTGCGAAGGCCCGGGACCGA
TGA

Upstream 100 bases:

>100_bases
CGGACTCGACGACGCCGGCGCGATGCATCGCACCGCGGCGCAATGCGGCCTTGCCGCGTCGGCGGGTCCCATCCCATCGA
ACACAACGGAGCTCCTCGAC

Downstream 100 bases:

>100_bases
AGCTGCGGCCCGCGCGGCGCGCTCAGCGCCGTGCGGGATCGAAGTGCCGGCGCAGGCCCTGCCAGCAGCGCGCGTAGTCG
GCCTGCCGCAGCGGCGAGGC

Product: alcohol dehydrogenase large subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MHSWKAVLRHGATPLILAATLAGSPCASATPATPVNAARLAAAAQEPANWMTHGGTYQEARYSPLDQINTRSIARLKLAW
YGDFDTSRGQESTPLVIDGVMYTTSSWSKVYAYDAATGKLLWRHDPKVPGDRGADACCDVVNRGVAAWNGKVYVGTLDGR
LEALDAKTGKLVWSTVTVDQTRPYTITGAPRVVKGKVLIGNGGAEYGVRGYVSAYDAETGALAWRFYMTPNPENKPDGAA
SDAILMSKAYGTWHDGAWKQTGGGGTPWDAIVYDTDFDQVIIGTGNGNPWSWEHRSGSKGDNLFLGSLLALDAETGAYKW
HYQETPSENWDFTSTQPIILTELTLQGRQRKALLHAPKNGFFYVVDRKDGALISAEPFTTVNWATGIDLKTGRPIEAPGA
RYERTKKSFWAMPGPFGSHNWHPMAFSPKTGLTYIPVQDVPLDYNYSPDFKYSPQRGTWNTGIEATTFAGPGSESHRRLL
AMQTRGALVAWDAVRQKEAWRVQHGNLASAGVLATGGNLVFQGTPDGRLVAYTADTGRQVWSWQGFDGIIAGAMTYAVGG
EQYVAVVAGFGGSNALHAPFAVAPKVGLHGRILAFKLDGRAVLPDNTRPLLPPNVPEQTWPAETVSRGAALYGHCAACHG
FGTYAANVIPDLRRSPMLSVKSAWDAVVLGGALADKGMPNWTGRIAAEDVEAIRAYVVDRARQLRDDEAAAQAAAKARDR

Sequences:

>Translated_720_residues
MHSWKAVLRHGATPLILAATLAGSPCASATPATPVNAARLAAAAQEPANWMTHGGTYQEARYSPLDQINTRSIARLKLAW
YGDFDTSRGQESTPLVIDGVMYTTSSWSKVYAYDAATGKLLWRHDPKVPGDRGADACCDVVNRGVAAWNGKVYVGTLDGR
LEALDAKTGKLVWSTVTVDQTRPYTITGAPRVVKGKVLIGNGGAEYGVRGYVSAYDAETGALAWRFYMTPNPENKPDGAA
SDAILMSKAYGTWHDGAWKQTGGGGTPWDAIVYDTDFDQVIIGTGNGNPWSWEHRSGSKGDNLFLGSLLALDAETGAYKW
HYQETPSENWDFTSTQPIILTELTLQGRQRKALLHAPKNGFFYVVDRKDGALISAEPFTTVNWATGIDLKTGRPIEAPGA
RYERTKKSFWAMPGPFGSHNWHPMAFSPKTGLTYIPVQDVPLDYNYSPDFKYSPQRGTWNTGIEATTFAGPGSESHRRLL
AMQTRGALVAWDAVRQKEAWRVQHGNLASAGVLATGGNLVFQGTPDGRLVAYTADTGRQVWSWQGFDGIIAGAMTYAVGG
EQYVAVVAGFGGSNALHAPFAVAPKVGLHGRILAFKLDGRAVLPDNTRPLLPPNVPEQTWPAETVSRGAALYGHCAACHG
FGTYAANVIPDLRRSPMLSVKSAWDAVVLGGALADKGMPNWTGRIAAEDVEAIRAYVVDRARQLRDDEAAAQAAAKARDR
>Mature_720_residues
MHSWKAVLRHGATPLILAATLAGSPCASATPATPVNAARLAAAAQEPANWMTHGGTYQEARYSPLDQINTRSIARLKLAW
YGDFDTSRGQESTPLVIDGVMYTTSSWSKVYAYDAATGKLLWRHDPKVPGDRGADACCDVVNRGVAAWNGKVYVGTLDGR
LEALDAKTGKLVWSTVTVDQTRPYTITGAPRVVKGKVLIGNGGAEYGVRGYVSAYDAETGALAWRFYMTPNPENKPDGAA
SDAILMSKAYGTWHDGAWKQTGGGGTPWDAIVYDTDFDQVIIGTGNGNPWSWEHRSGSKGDNLFLGSLLALDAETGAYKW
HYQETPSENWDFTSTQPIILTELTLQGRQRKALLHAPKNGFFYVVDRKDGALISAEPFTTVNWATGIDLKTGRPIEAPGA
RYERTKKSFWAMPGPFGSHNWHPMAFSPKTGLTYIPVQDVPLDYNYSPDFKYSPQRGTWNTGIEATTFAGPGSESHRRLL
AMQTRGALVAWDAVRQKEAWRVQHGNLASAGVLATGGNLVFQGTPDGRLVAYTADTGRQVWSWQGFDGIIAGAMTYAVGG
EQYVAVVAGFGGSNALHAPFAVAPKVGLHGRILAFKLDGRAVLPDNTRPLLPPNVPEQTWPAETVSRGAALYGHCAACHG
FGTYAANVIPDLRRSPMLSVKSAWDAVVLGGALADKGMPNWTGRIAAEDVEAIRAYVVDRARQLRDDEAAAQAAAKARDR

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is not a substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=396, Percent_Identity=26.010101010101, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF00034 Cytochrom_C; PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 77704; Mature: 77704

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSWKAVLRHGATPLILAATLAGSPCASATPATPVNAARLAAAAQEPANWMTHGGTYQEA
CCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCCCC
RYSPLDQINTRSIARLKLAWYGDFDTSRGQESTPLVIDGVMYTTSSWSKVYAYDAATGKL
CCCCHHHCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCEE
LWRHDPKVPGDRGADACCDVVNRGVAAWNGKVYVGTLDGRLEALDAKTGKLVWSTVTVDQ
EEEECCCCCCCCCHHHHHHHHHCCEEEECCEEEEEECCCEEEEECCCCCEEEEEEEEECC
TRPYTITGAPRVVKGKVLIGNGGAEYGVRGYVSAYDAETGALAWRFYMTPNPENKPDGAA
CCCEEECCCCEEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCC
SDAILMSKAYGTWHDGAWKQTGGGGTPWDAIVYDTDFDQVIIGTGNGNPWSWEHRSGSKG
CCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCC
DNLFLGSLLALDAETGAYKWHYQETPSENWDFTSTQPIILTELTLQGRQRKALLHAPKNG
CCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCC
FFYVVDRKDGALISAEPFTTVNWATGIDLKTGRPIEAPGARYERTKKSFWAMPGPFGSHN
EEEEEECCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
WHPMAFSPKTGLTYIPVQDVPLDYNYSPDFKYSPQRGTWNTGIEATTFAGPGSESHRRLL
CCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHCEEE
AMQTRGALVAWDAVRQKEAWRVQHGNLASAGVLATGGNLVFQGTPDGRLVAYTADTGRQV
EEECCCCEEEEHHHHCCHHEEEECCCCCCCCEEEECCEEEEEECCCCEEEEEECCCCCEE
WSWQGFDGIIAGAMTYAVGGEQYVAVVAGFGGSNALHAPFAVAPKVGLHGRILAFKLDGR
EEECCCCHHHHHHHHEECCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEEEECCE
AVLPDNTRPLLPPNVPEQTWPAETVSRGAALYGHCAACHGFGTYAANVIPDLRRSPMLSV
EECCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHCHHHHCCCCEEH
KSAWDAVVLGGALADKGMPNWTGRIAAEDVEAIRAYVVDRARQLRDDEAAAQAAAKARDR
HCCCCEEEECCHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MHSWKAVLRHGATPLILAATLAGSPCASATPATPVNAARLAAAAQEPANWMTHGGTYQEA
CCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCCCC
RYSPLDQINTRSIARLKLAWYGDFDTSRGQESTPLVIDGVMYTTSSWSKVYAYDAATGKL
CCCCHHHCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCEE
LWRHDPKVPGDRGADACCDVVNRGVAAWNGKVYVGTLDGRLEALDAKTGKLVWSTVTVDQ
EEEECCCCCCCCCHHHHHHHHHCCEEEECCEEEEEECCCEEEEECCCCCEEEEEEEEECC
TRPYTITGAPRVVKGKVLIGNGGAEYGVRGYVSAYDAETGALAWRFYMTPNPENKPDGAA
CCCEEECCCCEEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCC
SDAILMSKAYGTWHDGAWKQTGGGGTPWDAIVYDTDFDQVIIGTGNGNPWSWEHRSGSKG
CCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCC
DNLFLGSLLALDAETGAYKWHYQETPSENWDFTSTQPIILTELTLQGRQRKALLHAPKNG
CCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCC
FFYVVDRKDGALISAEPFTTVNWATGIDLKTGRPIEAPGARYERTKKSFWAMPGPFGSHN
EEEEEECCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
WHPMAFSPKTGLTYIPVQDVPLDYNYSPDFKYSPQRGTWNTGIEATTFAGPGSESHRRLL
CCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHCEEE
AMQTRGALVAWDAVRQKEAWRVQHGNLASAGVLATGGNLVFQGTPDGRLVAYTADTGRQV
EEECCCCEEEEHHHHCCHHEEEECCCCCCCCEEEECCEEEEEECCCCEEEEEECCCCCEE
WSWQGFDGIIAGAMTYAVGGEQYVAVVAGFGGSNALHAPFAVAPKVGLHGRILAFKLDGR
EEECCCCHHHHHHHHEECCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEEEECCE
AVLPDNTRPLLPPNVPEQTWPAETVSRGAALYGHCAACHGFGTYAANVIPDLRRSPMLSV
EECCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHHCHHHHCCCCEEH
KSAWDAVVLGGALADKGMPNWTGRIAAEDVEAIRAYVVDRARQLRDDEAAAQAAAKARDR
HCCCCEEEECCHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA