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The map label for this gene is pdxA [H]

Identifier: 124266039

GI number: 124266039

Start: 881576

End: 882589

Strand: Direct

Name: pdxA [H]

Synonym: Mpe_A0846

Alternate gene names: 124266039

Gene position: 881576-882589 (Clockwise)

Preceding gene: 124266038

Following gene: 124266042

Centisome position: 21.8

GC content: 75.35

Gene sequence:

>1014_bases
ATGCAGCTGCCGCTGGCGATCACGATGGGCGATGCCTGCGGCATCGGCCCGGAGATCATCGCGTCGGCCTTCCTGCGCGA
TGCGCTGCCGGGTGGCTTCGCGGTTGGCGATGTCGAGGTGCTGCGGCGCGCCGCGGCCCTGGTCTCGGCGTCGGACCACG
CCCTGCTGCCGGTGGCCCGGATCGAGCGTCCGGCCGACGTGGCCGGCGTGCCGCCGCGCTGCCTGCCGGTGCTGGTGCCG
CCGGGGCTGCCGGCCGGCCTGGCGGCGCGACCCTTCGGCCGCGTCGACGCTGCGGCGGGTGCGGCCGCCGCGGTCTGCAT
CCGGCACGCCGTGGCGCTGGCGCAGGCCGGCGAGGTGGCGGCGATCGTCACCGCGCCGATCCACAAGGAGGCGCTGGCCG
CCGCCGGCGAGCCCTACCCGGGGCACACCGAGCTGCTGCAGGCCGAGGCCGGCGCCGGGCCGGTGCGCATGATGCTCGCG
AACGACGAACTCAAGACCGTGCTGGTCAGCATCCACGTCTCGCTGCGCCGGGCGATCGACGCCGTGAGCACGGCGTCGGT
GCTCGAGACGCTGCGCATCGCGCACGCCGCAGCGCGGCGCTGGGGCCAGGCCGCGCCGCGCATCGCCGTGGCCGGACTCA
ACCCGCACGCGGGCGAGGGTGGCCTGTTCGGCGACGAGGAACTGCGCGTCATCGCGCCGGCCATCGAGGCGGCGTGCCGC
GAGGGCATCGACGCGCGCGGGCCGTTCGCACCCGACACCGTGTTCATGCGCGCCCGCCACACGGTCGACCACCCGGGCGA
GTTCGACATCGTGGTGGCGATGTACCACGACCAAGGGCTGATCCCGGTGAAGTACCTCGGGGTCGAGCGCGGCGTCAACG
TGACGCTGGGACTGCCCTTCGTGCGCACCAGCCCCGATCACGGCACCGCGTTCGATCGGGTCGGCAGTGGCCGCGCCGAC
CCGTCCAGCCTGATCGCCGCCGGCCAGATGGCGCGCCGCCTCGCGGCTGGCTGA

Upstream 100 bases:

>100_bases
AGCGCTTCGGTGCCCCCGCGCTCGGTGCCCACGTGGCGCAGCTGTTCGACCTCGAGCACGAGTTCATCGACATCGACAAC
CCGGCGTGAGCCCGTCCCGC

Downstream 100 bases:

>100_bases
CCGCCGGGCGCCTCAGAGACGGCTGCTGGTCGCCGTGCTGCGCGGGGCCGCACCGCCCAGCTGCGCCAGCTGCTTGCGGG
CACGCGCCGTCGCGCGCTCG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQLPLAITMGDACGIGPEIIASAFLRDALPGGFAVGDVEVLRRAAALVSASDHALLPVARIERPADVAGVPPRCLPVLVP
PGLPAGLAARPFGRVDAAAGAAAAVCIRHAVALAQAGEVAAIVTAPIHKEALAAAGEPYPGHTELLQAEAGAGPVRMMLA
NDELKTVLVSIHVSLRRAIDAVSTASVLETLRIAHAAARRWGQAAPRIAVAGLNPHAGEGGLFGDEELRVIAPAIEAACR
EGIDARGPFAPDTVFMRARHTVDHPGEFDIVVAMYHDQGLIPVKYLGVERGVNVTLGLPFVRTSPDHGTAFDRVGSGRAD
PSSLIAAGQMARRLAAG

Sequences:

>Translated_337_residues
MQLPLAITMGDACGIGPEIIASAFLRDALPGGFAVGDVEVLRRAAALVSASDHALLPVARIERPADVAGVPPRCLPVLVP
PGLPAGLAARPFGRVDAAAGAAAAVCIRHAVALAQAGEVAAIVTAPIHKEALAAAGEPYPGHTELLQAEAGAGPVRMMLA
NDELKTVLVSIHVSLRRAIDAVSTASVLETLRIAHAAARRWGQAAPRIAVAGLNPHAGEGGLFGDEELRVIAPAIEAACR
EGIDARGPFAPDTVFMRARHTVDHPGEFDIVVAMYHDQGLIPVKYLGVERGVNVTLGLPFVRTSPDHGTAFDRVGSGRAD
PSSLIAAGQMARRLAAG
>Mature_337_residues
MQLPLAITMGDACGIGPEIIASAFLRDALPGGFAVGDVEVLRRAAALVSASDHALLPVARIERPADVAGVPPRCLPVLVP
PGLPAGLAARPFGRVDAAAGAAAAVCIRHAVALAQAGEVAAIVTAPIHKEALAAAGEPYPGHTELLQAEAGAGPVRMMLA
NDELKTVLVSIHVSLRRAIDAVSTASVLETLRIAHAAARRWGQAAPRIAVAGLNPHAGEGGLFGDEELRVIAPAIEAACR
EGIDARGPFAPDTVFMRARHTVDHPGEFDIVVAMYHDQGLIPVKYLGVERGVNVTLGLPFVRTSPDHGTAFDRVGSGRAD
PSSLIAAGQMARRLAAG

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=332, Percent_Identity=37.6506024096386, Blast_Score=188, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34665; Mature: 34665

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPLAITMGDACGIGPEIIASAFLRDALPGGFAVGDVEVLRRAAALVSASDHALLPVAR
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCCCCCCHHH
IERPADVAGVPPRCLPVLVPPGLPAGLAARPFGRVDAAAGAAAAVCIRHAVALAQAGEVA
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
AIVTAPIHKEALAAAGEPYPGHTELLQAEAGAGPVRMMLANDELKTVLVSIHVSLRRAID
EEEECCHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
AVSTASVLETLRIAHAAARRWGQAAPRIAVAGLNPHAGEGGLFGDEELRVIAPAIEAACR
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHH
EGIDARGPFAPDTVFMRARHTVDHPGEFDIVVAMYHDQGLIPVKYLGVERGVNVTLGLPF
CCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCEEEEECCE
VRTSPDHGTAFDRVGSGRADPSSLIAAGQMARRLAAG
EECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLPLAITMGDACGIGPEIIASAFLRDALPGGFAVGDVEVLRRAAALVSASDHALLPVAR
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCCCCCCHHH
IERPADVAGVPPRCLPVLVPPGLPAGLAARPFGRVDAAAGAAAAVCIRHAVALAQAGEVA
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
AIVTAPIHKEALAAAGEPYPGHTELLQAEAGAGPVRMMLANDELKTVLVSIHVSLRRAID
EEEECCHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
AVSTASVLETLRIAHAAARRWGQAAPRIAVAGLNPHAGEGGLFGDEELRVIAPAIEAACR
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHH
EGIDARGPFAPDTVFMRARHTVDHPGEFDIVVAMYHDQGLIPVKYLGVERGVNVTLGLPF
CCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCEEEEECCE
VRTSPDHGTAFDRVGSGRADPSSLIAAGQMARRLAAG
EECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA