Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 124265981

GI number: 124265981

Start: 823261

End: 824361

Strand: Reverse

Name: fabD [H]

Synonym: Mpe_A0788

Alternate gene names: 124265981

Gene position: 824361-823261 (Counterclockwise)

Preceding gene: 124265982

Following gene: 124265980

Centisome position: 20.38

GC content: 75.57

Gene sequence:

>1101_bases
GTGCGCGACTACGCCATCGTCTGCCCCGGCCAGGGCACGCAGTCGCCCGACATGTTCGACTTGGTGGCCGCGCACCCGCG
CGGCCTCGCGGTGCTGCAGGACTTCGGCGCGGCGCTCGGCCGCGACCTGGTGGCCGAGGCGCAGGCCGGCACCGGCCTGC
ACGCGAACGCCTGGGCGCAACCGGCGCTGGTGGCGCTGGCCCGCGCCAGCTGGGAGATCCTGGCGCCCGAGCTGCCGGCG
GCGCCCGCGGCATTCGCCGGCTACAGCGTGGGCGAGGTGTCGGCCTGGAGTTGCGCCGGCGCCTGGGACGTGGCGGGCTC
GGCGCGCCTCGCCGCCACCCGCGCCGCGCTGATGGACGCCGCCAGGCCCGCCCGGCAGCGGCATGCTCGCGGTGCGCGGC
CTGCCGCTGCGGTCGGATCACCGAACAGGCCGGCGCCGCCGGCCTGCACGTGGCCATCGTCAACGGTGACGACCATGCGG
TGCTGGCCGGGCCGACCGCTGCGCTCGACAGGGCCGAGGCCGAGCTGGCGCCGCGCGGCGCCTGGCTGCGCCGGCTCGAA
GTGCAGGTGCCCTCGCACACGCCGCTGCTGGCGGCGGCGGCCCAGCGCTTCGCGGCCGTGGTGGCCGACGCGCCGGCGCG
GGCGCCGGCTGCCCCGGTGCTGCGCGGCATCGACGGGCGACGCTGCTTCGACGCGGCAGGCGGTCTGGCCGCGCTGGCCC
GCGCGATCGCCGAGCCAGTGCGCTGGGCCGACTGCATGCGCGAGCTGTCCGAGAGCGGCGTGCGAGTGGTGCTGGAACTC
GGCCCCGGACGCTCGCTGGCCAAGCTGCTGGCCGAGGCCCAGCCCGACATCGATGTCCGCTCGGTCGCCGATTTCCGCTC
CTGGCGCGGCGTGGCCGACTGGCTGCGGGTCCGGCTCGACGCCTGAGGCGGCGGCGACCCGCCGCCTTCGCCACACCGCC
CCTCCGACCGCGTCCGCCAGCCCCGGTGAAACCCCGAGTCCGGAGGGCTTGACGGACTCTTTGTCGGCAACTAATATATT
AGTACCATACCGACAATCGGAGACCCGCCATGATGACCGAACGTCAACGCAAGTTCCGTGA

Upstream 100 bases:

>100_bases
TGGTGGAGCGCTGGTTGAGCCCGGGCGGCAGCGCCGACCTGCTGGCGGCCTGCCTGTTCGTCGCCGCCCTCGAACCGGCG
CGCTGAGGAAGGCCCTCCGG

Downstream 100 bases:

>100_bases
ACAGTACAAGTCCAACATCAGCCCGCTCTACAACGGCCTGCTGCACGTCGCGGTGATGTTCGCCGCCGGCATCGGCGGCA
TCTGGTACTGCGCCACGCAG

Product: acyl-carrier-protein S-malonyltransferase-like protein

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRDYAIVCPGQGTQSPDMFDLVAAHPRGLAVLQDFGAALGRDLVAEAQAGTGLHANAWAQPALVALARASWEILAPELPA
APAAFAGYSVGEVSAWSCAGAWDVAGSARLAATRAALMDAARPARQRHARGARPAAAVGSPNRPAPPACTWPSSTVTTMR
CWPGRPLRSTGPRPSWRRAAPGCAGSKCRCPRTRRCWRRRPSASRPWWPTRRRGRRLPRCCAASTGDAASTRQAVWPRWP
ARSPSQCAGPTACASCPRAACEWCWNSAPDARWPSCWPRPSPTSMSARSPISAPGAAWPTGCGSGSTPEAAATRRLRHTA
PPTASASPGETPSPEGLTDSLSATNILVPYRQSETRHDDRTSTQVP

Sequences:

>Translated_366_residues
MRDYAIVCPGQGTQSPDMFDLVAAHPRGLAVLQDFGAALGRDLVAEAQAGTGLHANAWAQPALVALARASWEILAPELPA
APAAFAGYSVGEVSAWSCAGAWDVAGSARLAATRAALMDAARPARQRHARGARPAAAVGSPNRPAPPACTWPSSTVTTMR
CWPGRPLRSTGPRPSWRRAAPGCAGSKCRCPRTRRCWRRRPSASRPWWPTRRRGRRLPRCCAASTGDAASTRQAVWPRWP
ARSPSQCAGPTACASCPRAACEWCWNSAPDARWPSCWPRPSPTSMSARSPISAPGAAWPTGCGSGSTPEAAATRRLRHTA
PPTASASPGETPSPEGLTDSLSATNILVPYRQSETRHDDRTSTQVP
>Mature_366_residues
MRDYAIVCPGQGTQSPDMFDLVAAHPRGLAVLQDFGAALGRDLVAEAQAGTGLHANAWAQPALVALARASWEILAPELPA
APAAFAGYSVGEVSAWSCAGAWDVAGSARLAATRAALMDAARPARQRHARGARPAAAVGSPNRPAPPACTWPSSTVTTMR
CWPGRPLRSTGPRPSWRRAAPGCAGSKCRCPRTRRCWRRRPSASRPWWPTRRRGRRLPRCCAASTGDAASTRQAVWPRWP
ARSPSQCAGPTACASCPRAACEWCWNSAPDARWPSCWPRPSPTSMSARSPISAPGAAWPTGCGSGSTPEAAATRRLRHTA
PPTASASPGETPSPEGLTDSLSATNILVPYRQSETRHDDRTSTQVP

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Escherichia coli, GI1787334, Length=152, Percent_Identity=36.1842105263158, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 38759; Mature: 38759

Theoretical pI: Translated: 11.41; Mature: 11.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDYAIVCPGQGTQSPDMFDLVAAHPRGLAVLQDFGAALGRDLVAEAQAGTGLHANAWAQ
CCCCEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
PALVALARASWEILAPELPAAPAAFAGYSVGEVSAWSCAGAWDVAGSARLAATRAALMDA
HHHHHHHHHCHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ARPARQRHARGARPAAAVGSPNRPAPPACTWPSSTVTTMRCWPGRPLRSTGPRPSWRRAA
HHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHCC
PGCAGSKCRCPRTRRCWRRRPSASRPWWPTRRRGRRLPRCCAASTGDAASTRQAVWPRWP
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHCCCCCCHHHHHHHHCCCCC
ARSPSQCAGPTACASCPRAACEWCWNSAPDARWPSCWPRPSPTSMSARSPISAPGAAWPT
CCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GCGSGSTPEAAATRRLRHTAPPTASASPGETPSPEGLTDSLSATNILVPYRQSETRHDDR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
TSTQVP
CCCCCC
>Mature Secondary Structure
MRDYAIVCPGQGTQSPDMFDLVAAHPRGLAVLQDFGAALGRDLVAEAQAGTGLHANAWAQ
CCCCEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
PALVALARASWEILAPELPAAPAAFAGYSVGEVSAWSCAGAWDVAGSARLAATRAALMDA
HHHHHHHHHCHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ARPARQRHARGARPAAAVGSPNRPAPPACTWPSSTVTTMRCWPGRPLRSTGPRPSWRRAA
HHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHCC
PGCAGSKCRCPRTRRCWRRRPSASRPWWPTRRRGRRLPRCCAASTGDAASTRQAVWPRWP
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHCCCCCCHHHHHHHHCCCCC
ARSPSQCAGPTACASCPRAACEWCWNSAPDARWPSCWPRPSPTSMSARSPISAPGAAWPT
CCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GCGSGSTPEAAATRRLRHTAPPTASASPGETPSPEGLTDSLSATNILVPYRQSETRHDDR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
TSTQVP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]