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The map label for this gene is mdcB [H]

Identifier: 124265982

GI number: 124265982

Start: 824376

End: 825236

Strand: Reverse

Name: mdcB [H]

Synonym: Mpe_A0789

Alternate gene names: 124265982

Gene position: 825236-824376 (Counterclockwise)

Preceding gene: 124265983

Following gene: 124265981

Centisome position: 20.41

GC content: 77.35

Gene sequence:

>861_bases
ATGCTGAGCCTGACGACGCCTCCCTCGCTCCTGCATGCCGACCCGGAGTGCGGCCACGCGCCGCGCACCGTGCGCAACGC
CGCGGTGCGGGCGCTGCTGGGCGAGCTGATCACCTACCCCAAGCCGGGCCTCGTGAGCCTGTGCGACAGCGGCAGCCACC
GCGACATGGACGCCGCGAGCTTCGTGCGCAGCAGCCTGGCGCTGCGCCGCTACTTCGAGCAGGCCGCCGCGGCCGGCGCC
CAGGGCGCGAGCTTCGCCACGCTGAACCGGCTGGGGCGTGCCGCCGAGGCACGCATGCTGCGCGCGACCGGCGGCGTCAA
CACCCACCGCGGCGCGATCTTCAACCTCGGCCTACTGGCGGCAGCGGCCGGGGCGCGCACGCCGCGGGACCGCGCGCCGC
TCGGCGAGCGCGTGCGACAGCTGTGGGGCGCCGATATCGCCGCGCACCGGCGTGACGGCGGCAGCCATGGCAGCCGCGTC
ACTGCCGCGCACGGCGCCGGCGGCGCGCAGGCCGAGGCGGCCGCCGGCTTCCCTTCCGTCTACCGCCTCGCGCTGCCGGC
CTACCGCGACGCGCTGGCGCGCAGCGGCGCCGCCAACGCGGCGCGCGTGCAGGCCTTCTTCACGCTGATGGCCGAGCTGG
CCGACACCAACCTGCTGCACCGCGGCGGCGCCGCCGGCCTCGCGTTCGCGCAGAGCGCCGCGCGCCAGTTCCTCGACGCC
GGCGGCGTCCACCGCAGCGGCTGGCAGTCGCACGCGGTGCGCGTGCACCGGCAGCTGGTGGAGCGCTGGTTGAGCCCGGG
CGGCAGCGCCGACCTGCTGGCGGCCTGCCTGTTCGTCGCCGCCCTCGAACCGGCGCGCTGA

Upstream 100 bases:

>100_bases
TGGCAGCCGCGCCGGCGCAGCTGCTGCTGAAGGCCGACCACGGTCCGGCGCTGCGCGAACTGGCCGCGGTGTGGGCGGCC
TGGGGTACCGTGTCGACACC

Downstream 100 bases:

>100_bases
GGAAGGCCCTCCGGGTGCGCGACTACGCCATCGTCTGCCCCGGCCAGGGCACGCAGTCGCCCGACATGTTCGACTTGGTG
GCCGCGCACCCGCGCGGCCT

Product: triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLSLTTPPSLLHADPECGHAPRTVRNAAVRALLGELITYPKPGLVSLCDSGSHRDMDAASFVRSSLALRRYFEQAAAAGA
QGASFATLNRLGRAAEARMLRATGGVNTHRGAIFNLGLLAAAAGARTPRDRAPLGERVRQLWGADIAAHRRDGGSHGSRV
TAAHGAGGAQAEAAAGFPSVYRLALPAYRDALARSGAANAARVQAFFTLMAELADTNLLHRGGAAGLAFAQSAARQFLDA
GGVHRSGWQSHAVRVHRQLVERWLSPGGSADLLAACLFVAALEPAR

Sequences:

>Translated_286_residues
MLSLTTPPSLLHADPECGHAPRTVRNAAVRALLGELITYPKPGLVSLCDSGSHRDMDAASFVRSSLALRRYFEQAAAAGA
QGASFATLNRLGRAAEARMLRATGGVNTHRGAIFNLGLLAAAAGARTPRDRAPLGERVRQLWGADIAAHRRDGGSHGSRV
TAAHGAGGAQAEAAAGFPSVYRLALPAYRDALARSGAANAARVQAFFTLMAELADTNLLHRGGAAGLAFAQSAARQFLDA
GGVHRSGWQSHAVRVHRQLVERWLSPGGSADLLAACLFVAALEPAR
>Mature_286_residues
MLSLTTPPSLLHADPECGHAPRTVRNAAVRALLGELITYPKPGLVSLCDSGSHRDMDAASFVRSSLALRRYFEQAAAAGA
QGASFATLNRLGRAAEARMLRATGGVNTHRGAIFNLGLLAAAAGARTPRDRAPLGERVRQLWGADIAAHRRDGGSHGSRV
TAAHGAGGAQAEAAAGFPSVYRLALPAYRDALARSGAANAARVQAFFTLMAELADTNLLHRGGAAGLAFAQSAARQFLDA
GGVHRSGWQSHAVRVHRQLVERWLSPGGSADLLAACLFVAALEPAR

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=267, Percent_Identity=37.0786516853933, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 29818; Mature: 29818

Theoretical pI: Translated: 11.57; Mature: 11.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLTTPPSLLHADPECGHAPRTVRNAAVRALLGELITYPKPGLVSLCDSGSHRDMDAAS
CCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHH
FVRSSLALRRYFEQAAAAGAQGASFATLNRLGRAAEARMLRATGGVNTHRGAIFNLGLLA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AAAGARTPRDRAPLGERVRQLWGADIAAHRRDGGSHGSRVTAAHGAGGAQAEAAAGFPSV
HHHCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCEEEECCCCCCCCCHHHCCCHHH
YRLALPAYRDALARSGAANAARVQAFFTLMAELADTNLLHRGGAAGLAFAQSAARQFLDA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GGVHRSGWQSHAVRVHRQLVERWLSPGGSADLLAACLFVAALEPAR
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSLTTPPSLLHADPECGHAPRTVRNAAVRALLGELITYPKPGLVSLCDSGSHRDMDAAS
CCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHH
FVRSSLALRRYFEQAAAAGAQGASFATLNRLGRAAEARMLRATGGVNTHRGAIFNLGLLA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AAAGARTPRDRAPLGERVRQLWGADIAAHRRDGGSHGSRVTAAHGAGGAQAEAAAGFPSV
HHHCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCEEEECCCCCCCCCHHHCCCHHH
YRLALPAYRDALARSGAANAARVQAFFTLMAELADTNLLHRGGAAGLAFAQSAARQFLDA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GGVHRSGWQSHAVRVHRQLVERWLSPGGSADLLAACLFVAALEPAR
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10561613 [H]