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The map label for this gene is plsC [H]

Identifier: 124265903

GI number: 124265903

Start: 739737

End: 740486

Strand: Direct

Name: plsC [H]

Synonym: Mpe_A0710

Alternate gene names: 124265903

Gene position: 739737-740486 (Clockwise)

Preceding gene: 124265902

Following gene: 124265904

Centisome position: 18.29

GC content: 73.6

Gene sequence:

>750_bases
ATGCTGCGCCGTCTGCGTGCCGCGTGGCGCCTGCTGCGCGTGCTGCTGCACGTGTTGCACGGCCTGGCCATCGTGCTGAC
GATGTTCCGCGCGCTCGGGCGTACCGAGCGGCGCGAGCGCGTGCGCTGGTGGGCCGCCAAGATGCTGCGCGTGGCCGGGG
TCGGTGCCCGGCGCAGCGGCGAACCCTGGCCCGGCGGGGCGTTGCTGGTCGCGAACCACATCTCCTGGCTGGACATCGTG
GCCATCCACGCCTTCTGCCCGCAGGCGCGCTTCGTGTCCAAGGCGGACGTCCGGCACTGGCCGCTGCTGAGCCGGCTGAC
CGAGGCGGCCGACAGCCTCTACCTCGAGCGCGAGCGCAAGCGCGACGCGCTGCGCGTGGTGCACCAGATGGCCGAAGCAC
TGACGGCCGGCGACACCGTGGCGGTGTTCCCCGAAGGCACCACCGGCGAGGGCCACGCGCTGCTGCCCTTCCACGCCAAC
CTGCTGCAGGCTTCCATCGCCACCGGCACGCCGGTGCAGCCGGTGGCGCTGCGCTACCGCGACCGGCACGACGAGGTCAG
CAAGGCGGTGGCCTACGTCGGCGACACCACGCTGGTGCAGAGCCTGTGGTGGGTGGCCTGCGCCGACGGCTTGCAGGTGC
ACGTGCAGTTCCTCGCGCCGCAGGCCAGCGCGCAGGCCGAGCGCCGCGCGCTCGCCGAGCGCCTGCGCGCCGCGATCGAC
GAAGCCCTGCAGACGCCACCGACCACGTGA

Upstream 100 bases:

>100_bases
CCGGGGCGCGTGCGCGCCACCTTGGTCGCCGGCCACGTGGCGCACGAAGCCACGCGCGACGCGGCATGAGCGCCCGTCGC
GTCACCGCCGCGCCACCCTG

Downstream 100 bases:

>100_bases
TGTCCGCAGTGCGGCTATGTCTGCATTGCTGCGCCGTCGATCACCCCCTGCTGTTCCCGCAGGCTCCGCCGTCACCGGCA
CAGAGAGCGGCCGAACGTCG

Product: lyso-ornithine lipid acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLRRLRAAWRLLRVLLHVLHGLAIVLTMFRALGRTERRERVRWWAAKMLRVAGVGARRSGEPWPGGALLVANHISWLDIV
AIHAFCPQARFVSKADVRHWPLLSRLTEAADSLYLERERKRDALRVVHQMAEALTAGDTVAVFPEGTTGEGHALLPFHAN
LLQASIATGTPVQPVALRYRDRHDEVSKAVAYVGDTTLVQSLWWVACADGLQVHVQFLAPQASAQAERRALAERLRAAID
EALQTPPTT

Sequences:

>Translated_249_residues
MLRRLRAAWRLLRVLLHVLHGLAIVLTMFRALGRTERRERVRWWAAKMLRVAGVGARRSGEPWPGGALLVANHISWLDIV
AIHAFCPQARFVSKADVRHWPLLSRLTEAADSLYLERERKRDALRVVHQMAEALTAGDTVAVFPEGTTGEGHALLPFHAN
LLQASIATGTPVQPVALRYRDRHDEVSKAVAYVGDTTLVQSLWWVACADGLQVHVQFLAPQASAQAERRALAERLRAAID
EALQTPPTT
>Mature_249_residues
MLRRLRAAWRLLRVLLHVLHGLAIVLTMFRALGRTERRERVRWWAAKMLRVAGVGARRSGEPWPGGALLVANHISWLDIV
AIHAFCPQARFVSKADVRHWPLLSRLTEAADSLYLERERKRDALRVVHQMAEALTAGDTVAVFPEGTTGEGHALLPFHAN
LLQASIATGTPVQPVALRYRDRHDEVSKAVAYVGDTTLVQSLWWVACADGLQVHVQFLAPQASAQAERRALAERLRAAID
EALQTPPTT

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI33946291, Length=210, Percent_Identity=27.6190476190476, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27739; Mature: 27739

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRLRAAWRLLRVLLHVLHGLAIVLTMFRALGRTERRERVRWWAAKMLRVAGVGARRSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
EPWPGGALLVANHISWLDIVAIHAFCPQARFVSKADVRHWPLLSRLTEAADSLYLERERK
CCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RDALRVVHQMAEALTAGDTVAVFPEGTTGEGHALLPFHANLLQASIATGTPVQPVALRYR
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEECHHHHHHHHHHHCCCCCCCHHHHHHH
DRHDEVSKAVAYVGDTTLVQSLWWVACADGLQVHVQFLAPQASAQAERRALAERLRAAID
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EALQTPPTT
HHHCCCCCC
>Mature Secondary Structure
MLRRLRAAWRLLRVLLHVLHGLAIVLTMFRALGRTERRERVRWWAAKMLRVAGVGARRSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
EPWPGGALLVANHISWLDIVAIHAFCPQARFVSKADVRHWPLLSRLTEAADSLYLERERK
CCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RDALRVVHQMAEALTAGDTVAVFPEGTTGEGHALLPFHANLLQASIATGTPVQPVALRYR
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEECHHHHHHHHHHHCCCCCCCHHHHHHH
DRHDEVSKAVAYVGDTTLVQSLWWVACADGLQVHVQFLAPQASAQAERRALAERLRAAID
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EALQTPPTT
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8748025 [H]