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The map label for this gene is kpsT [H]

Identifier: 124265816

GI number: 124265816

Start: 658138

End: 658998

Strand: Reverse

Name: kpsT [H]

Synonym: Mpe_A0623

Alternate gene names: 124265816

Gene position: 658998-658138 (Counterclockwise)

Preceding gene: 124265817

Following gene: 124265815

Centisome position: 16.29

GC content: 65.62

Gene sequence:

>861_bases
ATGATCGAACTGCAGTCCGTCACCAAGTCGTACCCGACACCGCACGGGCGTCGCTATGTCTTCCGCGACCTCAGCTTCAC
CTTCCCCGAGAACGCCAGCATCGGCCTGATCGGCCCCAATGGTGCTGGCAAATCCACGCTGATGCGCCTGCTCGGCGGCA
TTGACTCGCCCGACCACGGCGTGGTGCGCAGCGACCGACGCATCTCCTGGCCGGTCGGCTTGGCGGGCGGCTTCCAGGGC
GCGCTGACCGGCCGCGACAACGTGCGCTTCGTCTGCCGCGTCTACGGCGCCACGGGCAGCGCCATGCGCGCAAAGGTCCG
CTTCACCGAGGAGTTCGCCGAGATCGGCGAGTATTTCGACCTGCCGGTGCGCTCGTATTCGTCGGGGATGCGCTCACGGC
TGGCGTTCGGGCTCAGCATGGCTTTCGATTTCGACTATTACCTGATCGACGAGGTCATGGCGGTCGGCGACGCGCAGTTC
CGCCTGAAGTGCCAGCAGATGTTCCGCGAGAAGCTTGCCACCTCCCGGCTGATCCTGGTGTCTCACAGCATGCGCGACAT
CAACGAGTTCTGCGACGTCGTCGTGCTGGTCGCCCGGGGCCAGGTCCGCATCTTCGAGGACGTGGCTGAAGGCATCGCCG
CCTATCAGGGCGATGCCGACAGCGCAGCGCTACCCAACTTCCCACCCTACATCCGCACGCGCACCGCCGCGCTGCGCTAT
CTCCATCAACTGGAAGCCCAGGCGTCCGGTATTCCCAGTGATGAACCGGACGCAGATGCTGCTCCTCTTCCGGCCTCAAG
CTCCGACGCGACGCCTCCTACCGCGGCTACCCCGACTCCTCCTTCTGCCACCCCGCGATGA

Upstream 100 bases:

>100_bases
AGCCTGCTGTACCCGATCGGCTGCGCGCTGGTGGCGCTGACACTCGGACTGATGCTTTACCGCGTACGCCGGCACCGGCT
GTTGGCCAGCTGAGCCCTCG

Downstream 100 bases:

>100_bases
GCCTTCTTCCTGCGCTGACTCCCCTGCGACTCAAGCTCGCCCTGATCGCCGCACCGATGCTGCTGGCCGGCGTGTATTAC
ACCTTCTTCGCCGCCGATCG

Product: ABC-type polysaccharide/polyol phosphate transport system ATPase component-like protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MIELQSVTKSYPTPHGRRYVFRDLSFTFPENASIGLIGPNGAGKSTLMRLLGGIDSPDHGVVRSDRRISWPVGLAGGFQG
ALTGRDNVRFVCRVYGATGSAMRAKVRFTEEFAEIGEYFDLPVRSYSSGMRSRLAFGLSMAFDFDYYLIDEVMAVGDAQF
RLKCQQMFREKLATSRLILVSHSMRDINEFCDVVVLVARGQVRIFEDVAEGIAAYQGDADSAALPNFPPYIRTRTAALRY
LHQLEAQASGIPSDEPDADAAPLPASSSDATPPTAATPTPPSATPR

Sequences:

>Translated_286_residues
MIELQSVTKSYPTPHGRRYVFRDLSFTFPENASIGLIGPNGAGKSTLMRLLGGIDSPDHGVVRSDRRISWPVGLAGGFQG
ALTGRDNVRFVCRVYGATGSAMRAKVRFTEEFAEIGEYFDLPVRSYSSGMRSRLAFGLSMAFDFDYYLIDEVMAVGDAQF
RLKCQQMFREKLATSRLILVSHSMRDINEFCDVVVLVARGQVRIFEDVAEGIAAYQGDADSAALPNFPPYIRTRTAALRY
LHQLEAQASGIPSDEPDADAAPLPASSSDATPPTAATPTPPSATPR
>Mature_286_residues
MIELQSVTKSYPTPHGRRYVFRDLSFTFPENASIGLIGPNGAGKSTLMRLLGGIDSPDHGVVRSDRRISWPVGLAGGFQG
ALTGRDNVRFVCRVYGATGSAMRAKVRFTEEFAEIGEYFDLPVRSYSSGMRSRLAFGLSMAFDFDYYLIDEVMAVGDAQF
RLKCQQMFREKLATSRLILVSHSMRDINEFCDVVVLVARGQVRIFEDVAEGIAAYQGDADSAALPNFPPYIRTRTAALRY
LHQLEAQASGIPSDEPDADAAPLPASSSDATPPTAATPTPPSATPR

Specific function: Putative ATP-binding protein, and an energy coupling component for the transport of polysialic acid across the cytoplasmic membrane [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=215, Percent_Identity=26.046511627907, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI27477115, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI47078218, Length=221, Percent_Identity=22.6244343891403, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI45446740, Length=221, Percent_Identity=22.6244343891403, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788761, Length=218, Percent_Identity=25.6880733944954, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790467, Length=214, Percent_Identity=24.2990654205607, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082267, Length=229, Percent_Identity=25.3275109170306, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081782, Length=179, Percent_Identity=29.0502793296089, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87081709, Length=213, Percent_Identity=23.4741784037559, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367384, Length=62, Percent_Identity=46.7741935483871, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: NA

EC number: 3.6.3.25 [C]

Molecular weight: Translated: 31213; Mature: 31213

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELQSVTKSYPTPHGRRYVFRDLSFTFPENASIGLIGPNGAGKSTLMRLLGGIDSPDHG
CCCHHHHHHHCCCCCCCEEEEECCEECCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCC
VVRSDRRISWPVGLAGGFQGALTGRDNVRFVCRVYGATGSAMRAKVRFTEEFAEIGEYFD
CEECCCEEECCCCCCCCCCCEECCCCCCEEEEEEECCCCCHHEEHHHHHHHHHHHHHHHC
LPVRSYSSGMRSRLAFGLSMAFDFDYYLIDEVMAVGDAQFRLKCQQMFREKLATSRLILV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEE
SHSMRDINEFCDVVVLVARGQVRIFEDVAEGIAAYQGDADSAALPNFPPYIRTRTAALRY
HHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
LHQLEAQASGIPSDEPDADAAPLPASSSDATPPTAATPTPPSATPR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIELQSVTKSYPTPHGRRYVFRDLSFTFPENASIGLIGPNGAGKSTLMRLLGGIDSPDHG
CCCHHHHHHHCCCCCCCEEEEECCEECCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCC
VVRSDRRISWPVGLAGGFQGALTGRDNVRFVCRVYGATGSAMRAKVRFTEEFAEIGEYFD
CEECCCEEECCCCCCCCCCCEECCCCCCEEEEEEECCCCCHHEEHHHHHHHHHHHHHHHC
LPVRSYSSGMRSRLAFGLSMAFDFDYYLIDEVMAVGDAQFRLKCQQMFREKLATSRLILV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEE
SHSMRDINEFCDVVVLVARGQVRIFEDVAEGIAAYQGDADSAALPNFPPYIRTRTAALRY
HHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
LHQLEAQASGIPSDEPDADAAPLPASSSDATPPTAATPTPPSATPR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1856162; 8051103 [H]