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The map label for this gene is kpsM [H]

Identifier: 124265817

GI number: 124265817

Start: 659006

End: 659815

Strand: Reverse

Name: kpsM [H]

Synonym: Mpe_A0624

Alternate gene names: 124265817

Gene position: 659815-659006 (Counterclockwise)

Preceding gene: 124265818

Following gene: 124265816

Centisome position: 16.32

GC content: 63.46

Gene sequence:

>810_bases
ATGCACGCCCCCCTCAGCAACCCACACTCGCGCAAGCGGACCGCTTGGGATATCCAACGCGCGGTCTTCCTCGCGCTGTT
CGTGCGAGAGCTCAAGACTCGCTTCGGCGGCCGCTGGCTGGGCGTGTTCTGGGTGTTGCTGGAGCCCACCGCCCACCTCG
CGATGCTGCTGGTGATCTTTGCGTTCATCCGGCACCGCCTGCTGCCGGGACTCGAATTCCCGGTGTTCCTGCTGACCGGC
TTGGTGCCGTTCTTCGTTTTCAGGAACCTGACACTGCGCGGGATGGATGCAATCGACAGCAACCGCGGATTGTTCGGATA
CCGACAGGTCAAGCCCATCGATCCGATGCTTGCGCGCGCGCTGCTGGAGGTTAGTCTCTACGGACTGATTTTCGTGACCA
TGCTCGCCGTGATGGGCTGGCTGGACATCGAGGTCGCGCCGCATCGGCCGCTCGAATGGCTGGGCGTGTTCGCTGTCGTG
GTTGTGCTCGGGTTTTCGCTGGGGCTGGTGTTCGCTGTATGCACCGACGACCTGCCAGAACTGCGCAGCTTCGTTCGCAT
CGTGTTCGTGCCGCTCTACCTGCTGTCGGGCGTGATGTTCCCGGTCGCCACGCTGTCGGAGTCGGTGCTGCCCTGGCTGC
TCTGGAACCCGATGCTGCACGCGATCGAGATCTCGCGCGGTTTCTTCTTCACCGGCTACCACGTCATTCCGCAAGTCAGC
CTGCTGTACCCGATCGGCTGCGCGCTGGTGGCGCTGACACTCGGACTGATGCTTTACCGCGTACGCCGGCACCGGCTGTT
GGCCAGCTGA

Upstream 100 bases:

>100_bases
CGAGCGTGCTGTTCGAATAGGAGGCTCTGCGGCCTGTGGTTCCGCCAGCAAGAAATCCGCCGCCCCGATCTCTGCGCCAC
AATTGAATGCCAAATCACCG

Downstream 100 bases:

>100_bases
GCCCTCGATGATCGAACTGCAGTCCGTCACCAAGTCGTACCCGACACCGCACGGGCGTCGCTATGTCTTCCGCGACCTCA
GCTTCACCTTCCCCGAGAAC

Product: kpsM protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MHAPLSNPHSRKRTAWDIQRAVFLALFVRELKTRFGGRWLGVFWVLLEPTAHLAMLLVIFAFIRHRLLPGLEFPVFLLTG
LVPFFVFRNLTLRGMDAIDSNRGLFGYRQVKPIDPMLARALLEVSLYGLIFVTMLAVMGWLDIEVAPHRPLEWLGVFAVV
VVLGFSLGLVFAVCTDDLPELRSFVRIVFVPLYLLSGVMFPVATLSESVLPWLLWNPMLHAIEISRGFFFTGYHVIPQVS
LLYPIGCALVALTLGLMLYRVRRHRLLAS

Sequences:

>Translated_269_residues
MHAPLSNPHSRKRTAWDIQRAVFLALFVRELKTRFGGRWLGVFWVLLEPTAHLAMLLVIFAFIRHRLLPGLEFPVFLLTG
LVPFFVFRNLTLRGMDAIDSNRGLFGYRQVKPIDPMLARALLEVSLYGLIFVTMLAVMGWLDIEVAPHRPLEWLGVFAVV
VVLGFSLGLVFAVCTDDLPELRSFVRIVFVPLYLLSGVMFPVATLSESVLPWLLWNPMLHAIEISRGFFFTGYHVIPQVS
LLYPIGCALVALTLGLMLYRVRRHRLLAS
>Mature_269_residues
MHAPLSNPHSRKRTAWDIQRAVFLALFVRELKTRFGGRWLGVFWVLLEPTAHLAMLLVIFAFIRHRLLPGLEFPVFLLTG
LVPFFVFRNLTLRGMDAIDSNRGLFGYRQVKPIDPMLARALLEVSLYGLIFVTMLAVMGWLDIEVAPHRPLEWLGVFAVV
VVLGFSLGLVFAVCTDDLPELRSFVRIVFVPLYLLSGVMFPVATLSESVLPWLLWNPMLHAIEISRGFFFTGYHVIPQVS
LLYPIGCALVALTLGLMLYRVRRHRLLAS

Specific function: KpsM and kpsT constitute a system for the transport of polysialic acid across the cytoplasmic membrane [H]

COG id: COG1682

COG function: function code GM; ABC-type polysaccharide/polyol phosphate export systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000412
- InterPro:   IPR013526
- InterPro:   IPR013525 [H]

Pfam domain/function: PF01061 ABC2_membrane [H]

EC number: NA

Molecular weight: Translated: 30570; Mature: 30570

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS51012 ABC_TM2 ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1856162; 7715449 [H]