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The map label for this gene is speH [H]

Identifier: 124265451

GI number: 124265451

Start: 278925

End: 279302

Strand: Reverse

Name: speH [H]

Synonym: Mpe_A0258

Alternate gene names: 124265451

Gene position: 279302-278925 (Counterclockwise)

Preceding gene: 124265455

Following gene: 124265450

Centisome position: 6.91

GC content: 73.54

Gene sequence:

>378_bases
ATGCAGGGTCTGCACCTCACCGCCGATTTGAGCGGCTGCCGCCGCGGCAGCCCGGCCCTGGTCGACGTGTCGGCGCTGCG
CGCGCTGTGCCTGGGGGCCGTTCTCGACGCCGGCCTGCAGCCGGTCGGCGAGTGCTTCCATCCCTTCCCTTCCGAGGACG
GCGAACCGCGCGGCGTCACCGGCGTGCTGCTGCTGGCCGAATCGCATCTCGCGGTGCACACGTGGCCCGAGCTGGACGCG
GTGACGCTCGACGTGTATGCGTGCCACCGCCACGCCGACAACTCGGCGCGTGCCGAGGTCGTGATCGCGCGGCTGATCGA
GGCCTTCGCGCCGGCGCGCGCCGAACGCCATGCGCTGCGCCGCGGGGCGGCCACATGA

Upstream 100 bases:

>100_bases
GGCGGGCGTGCGGGATTCGAGGGCAGCCATGGTTTGCAGGGGAAAAGGGCGCCACGGAAGCGGCAGAATCGACGATTTTA
CGAGCCCCGTCGCGCCACCC

Downstream 100 bases:

>100_bases
ACGCGCCCGCATTGATCCTCGCCGCCGGCCGCGGCGAGCGCATGAGCCCGCTGACCGACCACACACCCAAGCCGCTGCTG
CCGGTGCACGGCAAGCCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MQGLHLTADLSGCRRGSPALVDVSALRALCLGAVLDAGLQPVGECFHPFPSEDGEPRGVTGVLLLAESHLAVHTWPELDA
VTLDVYACHRHADNSARAEVVIARLIEAFAPARAERHALRRGAAT

Sequences:

>Translated_125_residues
MQGLHLTADLSGCRRGSPALVDVSALRALCLGAVLDAGLQPVGECFHPFPSEDGEPRGVTGVLLLAESHLAVHTWPELDA
VTLDVYACHRHADNSARAEVVIARLIEAFAPARAERHALRRGAAT
>Mature_125_residues
MQGLHLTADLSGCRRGSPALVDVSALRALCLGAVLDAGLQPVGECFHPFPSEDGEPRGVTGVLLLAESHLAVHTWPELDA
VTLDVYACHRHADNSARAEVVIARLIEAFAPARAERHALRRGAAT

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 13251; Mature: 13251

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLHLTADLSGCRRGSPALVDVSALRALCLGAVLDAGLQPVGECFHPFPSEDGEPRGVT
CCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCE
GVLLLAESHLAVHTWPELDAVTLDVYACHRHADNSARAEVVIARLIEAFAPARAERHALR
EEEEEECCCEEEEECCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
RGAAT
CCCCC
>Mature Secondary Structure
MQGLHLTADLSGCRRGSPALVDVSALRALCLGAVLDAGLQPVGECFHPFPSEDGEPRGVT
CCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCE
GVLLLAESHLAVHTWPELDAVTLDVYACHRHADNSARAEVVIARLIEAFAPARAERHALR
EEEEEECCCEEEEECCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
RGAAT
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]