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The map label for this gene is strD [H]

Identifier: 124265450

GI number: 124265450

Start: 278224

End: 278928

Strand: Reverse

Name: strD [H]

Synonym: Mpe_A0257

Alternate gene names: 124265450

Gene position: 278928-278224 (Counterclockwise)

Preceding gene: 124265451

Following gene: 124265449

Centisome position: 6.9

GC content: 68.65

Gene sequence:

>705_bases
ATGAACGCGCCCGCATTGATCCTCGCCGCCGGCCGCGGCGAGCGCATGAGCCCGCTGACCGACCACACACCCAAGCCGCT
GCTGCCGGTGCACGGCAAGCCGCTGATCGAGTGGCAGCTGGAGGCGCTGGCGCGCGACGGCGTGCGCCACGTGGTCATCA
ACACCGCCTGGCTCGAGGAGCAGTTCCCGGCCACGCTGGGCGACGGTTCGCGCTTCGGGCTGAGCATCCGCTACTCGATG
GAAGGCCGGCACTACGGCGGCGCGCTCGAAACCGCCGGCGGGATCGCCACCGCGCTGCCGCTGTTGCAATCGGACACCTT
TTGGGTCATGGCGGGCGATGCCTACATGCCCGGCTTCCGATTCGATGCGCTGCACGTGAACGACTTCATGGCCGGTGGCG
ATCTGGCCCACCTCTGGCTCGTGCCCAACCCGCCGCAACACCCCTGCGGCGACTTCGGCCTCAGTGACAAAGGCCGCATC
CTGGCGGGCGACGATGCGGCGGTCATCACTCGTTACACGTACTCCACGGTGGGCTTGTTCCAATCGAGACTGGTCGAGGG
CGTGCCGCCGGGGCAGAAGGCGCCGCTGCGACCTCATTTCGATGCGGCGATCGCCCGCGACCGGATCAGCGGCAGCCTCT
ACCTGGGGCCCTGGACCGACGTCGGTACGCCGCAACGCTGGCAGGCCTTGCAGGATGGGAGTTGA

Upstream 100 bases:

>100_bases
CCGACAACTCGGCGCGTGCCGAGGTCGTGATCGCGCGGCTGATCGAGGCCTTCGCGCCGGCGCGCGCCGAACGCCATGCG
CTGCGCCGCGGGGCGGCCAC

Downstream 100 bases:

>100_bases
GAGCGATGGACGGGGTGGGCTCACCGCTGCTCTGGTTGCTGAGCGTGCCGGTCGCCGTGCTGCTGCAGCGCGGCGCCGTG
CACGGCCTGCGCGCCGCCTG

Product: putative mannose-1-phosphate guanyltransferase-like protein

Products: NA

Alternate protein names: Sugar-nucleotidylation enzyme; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNAPALILAAGRGERMSPLTDHTPKPLLPVHGKPLIEWQLEALARDGVRHVVINTAWLEEQFPATLGDGSRFGLSIRYSM
EGRHYGGALETAGGIATALPLLQSDTFWVMAGDAYMPGFRFDALHVNDFMAGGDLAHLWLVPNPPQHPCGDFGLSDKGRI
LAGDDAAVITRYTYSTVGLFQSRLVEGVPPGQKAPLRPHFDAAIARDRISGSLYLGPWTDVGTPQRWQALQDGS

Sequences:

>Translated_234_residues
MNAPALILAAGRGERMSPLTDHTPKPLLPVHGKPLIEWQLEALARDGVRHVVINTAWLEEQFPATLGDGSRFGLSIRYSM
EGRHYGGALETAGGIATALPLLQSDTFWVMAGDAYMPGFRFDALHVNDFMAGGDLAHLWLVPNPPQHPCGDFGLSDKGRI
LAGDDAAVITRYTYSTVGLFQSRLVEGVPPGQKAPLRPHFDAAIARDRISGSLYLGPWTDVGTPQRWQALQDGS
>Mature_234_residues
MNAPALILAAGRGERMSPLTDHTPKPLLPVHGKPLIEWQLEALARDGVRHVVINTAWLEEQFPATLGDGSRFGLSIRYSM
EGRHYGGALETAGGIATALPLLQSDTFWVMAGDAYMPGFRFDALHVNDFMAGGDLAHLWLVPNPPQHPCGDFGLSDKGRI
LAGDDAAVITRYTYSTVGLFQSRLVEGVPPGQKAPLRPHFDAAIARDRISGSLYLGPWTDVGTPQRWQALQDGS

Specific function: Involved in the biosynthesis of the streptose moiety of streptomycin. Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=123, Percent_Identity=37.3983739837398, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI11761619, Length=123, Percent_Identity=37.3983739837398, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI133931050, Length=238, Percent_Identity=28.9915966386555, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005908
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 25363; Mature: 25363

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPALILAAGRGERMSPLTDHTPKPLLPVHGKPLIEWQLEALARDGVRHVVINTAWLEE
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEHHHH
QFPATLGDGSRFGLSIRYSMEGRHYGGALETAGGIATALPLLQSDTFWVMAGDAYMPGFR
HCCCCCCCCCEEEEEEEEEECCCCCCCCHHCCCCHHHHHHHHCCCCEEEEECCCCCCCEE
FDALHVNDFMAGGDLAHLWLVPNPPQHPCGDFGLSDKGRILAGDDAAVITRYTYSTVGLF
EEEEEECCEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCEEEEEEHHHHHHHH
QSRLVEGVPPGQKAPLRPHFDAAIARDRISGSLYLGPWTDVGTPQRWQALQDGS
HHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MNAPALILAAGRGERMSPLTDHTPKPLLPVHGKPLIEWQLEALARDGVRHVVINTAWLEE
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEHHHH
QFPATLGDGSRFGLSIRYSMEGRHYGGALETAGGIATALPLLQSDTFWVMAGDAYMPGFR
HCCCCCCCCCEEEEEEEEEECCCCCCCCHHCCCCHHHHHHHHCCCCEEEEECCCCCCCEE
FDALHVNDFMAGGDLAHLWLVPNPPQHPCGDFGLSDKGRILAGDDAAVITRYTYSTVGLF
EEEEEECCEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCEEEEEEHHHHHHHH
QSRLVEGVPPGQKAPLRPHFDAAIARDRISGSLYLGPWTDVGTPQRWQALQDGS
HHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3118332 [H]