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The map label for this gene is yisV [H]

Identifier: 124265376

GI number: 124265376

Start: 199714

End: 201138

Strand: Reverse

Name: yisV [H]

Synonym: Mpe_A0183

Alternate gene names: 124265376

Gene position: 201138-199714 (Counterclockwise)

Preceding gene: 124265392

Following gene: 124265375

Centisome position: 4.97

GC content: 74.88

Gene sequence:

>1425_bases
ATGCTGACCCGTGACGCCACCACCACGCTGACCGAGCAACTCGCCGAGCGCTACGCCGAGCGCATCCGCAGCCGCCTGCT
GGCGCCCGGCGCGCGGCTGCCGTCGGTGCGCGACTGCGCGCAGCGGCACGGCGTGAGCCCGCACACCGTGGTGGCCGCCT
ACGACCAGCTGCTTGCCCAGGGACTGATCGAGGCCCGTCGCCAGCGCGGCTTCTTTGTGCGCAATGCCGTCGCGCCGGCA
CGCAGCGCGCGTGCCGCGGCCCCGGCGGAAAGCCGTCCGGTCGCGCCGGTCGACGCAACGGCCTTGATCCGCAGCATGTT
CCACCACCCCGGCACCCGGCCCTCGCCCGGCCTGGGCACGCTGCCGCCCGAGTGGCTGGATCTCTCTCTGCTCGGCGGCG
CGCTGCGCCGCGTGAGCCAGGGCGACGGGCTGGCGGGCCACGCGCTGCACTACGGCGATCCGGCCGGCGACGGCCGGCTG
CGCGCGGCGCTGTCGCTGCGCCTGGCCGACCTCGGCATCGCCGCCGAGCCCGCGCAGATCGTCACGACGCTGGGCGCGAC
ACAGGCGCTCGACATCGTCTCGCGCACCTTGCTCGCGCCGGGCGACGCAGTACTGGTCGACGAGCCGGGCTGGGCCGTCG
AGTTCGCCCGCCTGGCCCAGCTCGGCATGCGCGTCTTGCCGGTTCCGCGCGGCGCCGACGGCCCCGATCTGGCGGTGATG
CGGCGCCTGATCGAGGCGCACCGGCCACGGCTCTACGTCACCGTCTCGGTCCTGCACAACCCGACCGGCTCCTCACTGTC
GCTGGCCGGCGCCCACCAGCTGCTGACGCTGGCGCAGGCGCACGACTTCCACATCGTCGAGGACGACACCTACGCCTGGC
TGGCCCCTGCGCACGCGCCACGCGTCGGCGCGCTCGACGGCCTGCAGCGCAGCATCTACATCTCGGGGTTCTCGAAGATC
CTCGCGCCGAGCTGGCGGGTCGGCTACATCGCCGCGCCGCCGGCCCTGGTGCAGCGGCTGGTCGATGTGAAGCTGCTGAC
GTCGCTGACGACGCCGGTGCTGACCGAGCAGGCCGTCGCGGTCTGCCTGGAGCAGGGCGCGCTGCGCCGCCATGCCGAGC
GTGTGGTGGTCCGGCTCGACGCCGCGCGCGCGCGCAGCATCGACCTGGCGCAGCGCCACGGCTGCACGACGGCCACGCCG
CCGCAGGGCCTGTTCGCCTGGCTCGACACCGGCGTCGACACCGACCGGCTGGCCCTGGCCCTGCTCGACGACGGCTGGCT
GATCGCGCCCGGCTCGCTGTTCCATGCCACGCGGCGGCCGAGCGGGCTGATGCGCATCAACGTCGCGACCTCTCAGGACC
CCGCGTTCTGGCGGGCGCTGGACCGCCGCCGCACCGAACTGCAGCGCCGCGGCGCGCGCGCTTGA

Upstream 100 bases:

>100_bases
GCATGCGAAAGCACTGTACGCTTCGAACCAATACACTAACAGTACAGAATCTCGCATCAACTACCGATCTGTACTGGCGC
TCCCGACGACACACGCCGCC

Downstream 100 bases:

>100_bases
GCGCGCGCACGGCACTTGCAAGCCTTGCGACGACCGGGTTGGCGTACAGACACTTACAATTGCCGCCACGCATGGACGAG
CCCACCATCCCTTTCGGCGA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MLTRDATTTLTEQLAERYAERIRSRLLAPGARLPSVRDCAQRHGVSPHTVVAAYDQLLAQGLIEARRQRGFFVRNAVAPA
RSARAAAPAESRPVAPVDATALIRSMFHHPGTRPSPGLGTLPPEWLDLSLLGGALRRVSQGDGLAGHALHYGDPAGDGRL
RAALSLRLADLGIAAEPAQIVTTLGATQALDIVSRTLLAPGDAVLVDEPGWAVEFARLAQLGMRVLPVPRGADGPDLAVM
RRLIEAHRPRLYVTVSVLHNPTGSSLSLAGAHQLLTLAQAHDFHIVEDDTYAWLAPAHAPRVGALDGLQRSIYISGFSKI
LAPSWRVGYIAAPPALVQRLVDVKLLTSLTTPVLTEQAVAVCLEQGALRRHAERVVVRLDAARARSIDLAQRHGCTTATP
PQGLFAWLDTGVDTDRLALALLDDGWLIAPGSLFHATRRPSGLMRINVATSQDPAFWRALDRRRTELQRRGARA

Sequences:

>Translated_474_residues
MLTRDATTTLTEQLAERYAERIRSRLLAPGARLPSVRDCAQRHGVSPHTVVAAYDQLLAQGLIEARRQRGFFVRNAVAPA
RSARAAAPAESRPVAPVDATALIRSMFHHPGTRPSPGLGTLPPEWLDLSLLGGALRRVSQGDGLAGHALHYGDPAGDGRL
RAALSLRLADLGIAAEPAQIVTTLGATQALDIVSRTLLAPGDAVLVDEPGWAVEFARLAQLGMRVLPVPRGADGPDLAVM
RRLIEAHRPRLYVTVSVLHNPTGSSLSLAGAHQLLTLAQAHDFHIVEDDTYAWLAPAHAPRVGALDGLQRSIYISGFSKI
LAPSWRVGYIAAPPALVQRLVDVKLLTSLTTPVLTEQAVAVCLEQGALRRHAERVVVRLDAARARSIDLAQRHGCTTATP
PQGLFAWLDTGVDTDRLALALLDDGWLIAPGSLFHATRRPSGLMRINVATSQDPAFWRALDRRRTELQRRGARA
>Mature_474_residues
MLTRDATTTLTEQLAERYAERIRSRLLAPGARLPSVRDCAQRHGVSPHTVVAAYDQLLAQGLIEARRQRGFFVRNAVAPA
RSARAAAPAESRPVAPVDATALIRSMFHHPGTRPSPGLGTLPPEWLDLSLLGGALRRVSQGDGLAGHALHYGDPAGDGRL
RAALSLRLADLGIAAEPAQIVTTLGATQALDIVSRTLLAPGDAVLVDEPGWAVEFARLAQLGMRVLPVPRGADGPDLAVM
RRLIEAHRPRLYVTVSVLHNPTGSSLSLAGAHQLLTLAQAHDFHIVEDDTYAWLAPAHAPRVGALDGLQRSIYISGFSKI
LAPSWRVGYIAAPPALVQRLVDVKLLTSLTTPVLTEQAVAVCLEQGALRRHAERVVVRLDAARARSIDLAQRHGCTTATP
PQGLFAWLDTGVDTDRLALALLDDGWLIAPGSLFHATRRPSGLMRINVATSQDPAFWRALDRRRTELQRRGARA

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=385, Percent_Identity=24.9350649350649, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI33469970, Length=385, Percent_Identity=24.9350649350649, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1787710, Length=458, Percent_Identity=29.0393013100437, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1790797, Length=479, Percent_Identity=28.39248434238, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51034; Mature: 51034

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRDATTTLTEQLAERYAERIRSRLLAPGARLPSVRDCAQRHGVSPHTVVAAYDQLLAQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
GLIEARRQRGFFVRNAVAPARSARAAAPAESRPVAPVDATALIRSMFHHPGTRPSPGLGT
HHHHHHHHCCCEEEHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
LPPEWLDLSLLGGALRRVSQGDGLAGHALHYGDPAGDGRLRAALSLRLADLGIAAEPAQI
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
VTTLGATQALDIVSRTLLAPGDAVLVDEPGWAVEFARLAQLGMRVLPVPRGADGPDLAVM
HHHHCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHH
RRLIEAHRPRLYVTVSVLHNPTGSSLSLAGAHQLLTLAQAHDFHIVEDDTYAWLAPAHAP
HHHHHHHCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCC
RVGALDGLQRSIYISGFSKILAPSWRVGYIAAPPALVQRLVDVKLLTSLTTPVLTEQAVA
CCCCHHHHHHHEEHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHH
VCLEQGALRRHAERVVVRLDAARARSIDLAQRHGCTTATPPQGLFAWLDTGVDTDRLALA
HHHHHHHHHHHHHHHHEEECHHHHHCHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHEEEE
LLDDGWLIAPGSLFHATRRPSGLMRINVATSQDPAFWRALDRRRTELQRRGARA
EECCCCEECCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLTRDATTTLTEQLAERYAERIRSRLLAPGARLPSVRDCAQRHGVSPHTVVAAYDQLLAQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
GLIEARRQRGFFVRNAVAPARSARAAAPAESRPVAPVDATALIRSMFHHPGTRPSPGLGT
HHHHHHHHCCCEEEHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
LPPEWLDLSLLGGALRRVSQGDGLAGHALHYGDPAGDGRLRAALSLRLADLGIAAEPAQI
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
VTTLGATQALDIVSRTLLAPGDAVLVDEPGWAVEFARLAQLGMRVLPVPRGADGPDLAVM
HHHHCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHH
RRLIEAHRPRLYVTVSVLHNPTGSSLSLAGAHQLLTLAQAHDFHIVEDDTYAWLAPAHAP
HHHHHHHCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCC
RVGALDGLQRSIYISGFSKILAPSWRVGYIAAPPALVQRLVDVKLLTSLTTPVLTEQAVA
CCCCHHHHHHHEEHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHH
VCLEQGALRRHAERVVVRLDAARARSIDLAQRHGCTTATPPQGLFAWLDTGVDTDRLALA
HHHHHHHHHHHHHHHHEEECHHHHHCHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHEEEE
LLDDGWLIAPGSLFHATRRPSGLMRINVATSQDPAFWRALDRRRTELQRRGARA
EECCCCEECCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]