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The map label for this gene is sucD [H]

Identifier: 124265264

GI number: 124265264

Start: 65634

End: 66527

Strand: Reverse

Name: sucD [H]

Synonym: Mpe_A0071

Alternate gene names: 124265264

Gene position: 66527-65634 (Counterclockwise)

Preceding gene: 124265265

Following gene: 124265263

Centisome position: 1.64

GC content: 66.89

Gene sequence:

>894_bases
ATGAGCATCCTGATCAACAAGAACACCAAGGTCATCACCCAGGGCATCACGGGCAAGACCGGTCAGTTCCACACGCGCGG
CTGCCGCGACTACGCCAACGGCAAGAACTGCTTCGTCGCCGGCGTCAACCCGAAGAAGGCCGGCGAGGACTTCGAGGGCA
TCCCGATCTACGCGAGCGTCAAGGAAGCCGCCGGGCAGACCGGCGCAACGGTGAGCGTGATCTACGTGCCGCCGGCGGGT
GCCGCGGCCGCGATCTGGGAGGCGGTCGAGGCCGACCTCGACCTCGCGATCTGCATCACCGAGGGCATCCCGGTGAAGGA
CATGCTGCTGGTGCGCAACAAGATGAAGGCCAAGGAGGCCGCCGGCGGCAAGAAGACCCTGCTGCTCGGCCCCAACTGTC
CGGGCCTGATCACGCCCGACGAGATCAAGATCGGCATCATGCCCGGCCACATCCACAAGAAGGGTCGCATCGGCGTGGTC
AGCCGCTCCGGCACCCTGACCTACGAGGCGGTGGCCCAGCTCAGCGAACTGGGCCTCGGCCAATCGAGCGCGGTCGGCAT
CGGCGGCGACCCGATCAACGGCCTGAAGCACATCGACGTGATGAGGGCCTTCAACGACGATCCGGACACTGACGCGGTGA
TCATGATCGGCGAGATCGGCGGCCCGGACGAGGCCGAGGCCGCACGCTGGTGCAAGGCGAACATGAAGAAGCCCATCGTC
GGCTTCATCGCCGGCGTGACCGCGCCTCCGGGCAAGCGCATGGGCCATGCCGGCGCGCTGATCTCCGGCGGCGCCGACAC
GGCTGACGCCAAGCTGGCGATCATGGAGGAGTGCGGCTTCACCGTCACCCGCAACCCGTCGGAGATGGGCAAGCTGCTCA
AGGGCCTGCTCTGA

Upstream 100 bases:

>100_bases
TGGCCGACTCCGGCCTGCCGATCATCGCCGCCGACACCATGGCCGAAGCAGCCACCAAGGTTGTCGCCGCCGTCGCCTGA
GCCCTCGAAGGACACCGAAC

Downstream 100 bases:

>100_bases
CCGCAGGCACGGGCGTCGCGCGACGCCCAGACAACTCCGCAAGGCCGCCCCAGGGCGGCCTTGTCCGTTACCGGCGCCGG
GCGGGCGTCGCATGCGTAGT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSILINKNTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASVKEAAGQTGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVKDMLLVRNKMKAKEAAGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHKKGRIGVV
SRSGTLTYEAVAQLSELGLGQSSAVGIGGDPINGLKHIDVMRAFNDDPDTDAVIMIGEIGGPDEAEAARWCKANMKKPIV
GFIAGVTAPPGKRMGHAGALISGGADTADAKLAIMEECGFTVTRNPSEMGKLLKGLL

Sequences:

>Translated_297_residues
MSILINKNTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASVKEAAGQTGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVKDMLLVRNKMKAKEAAGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHKKGRIGVV
SRSGTLTYEAVAQLSELGLGQSSAVGIGGDPINGLKHIDVMRAFNDDPDTDAVIMIGEIGGPDEAEAARWCKANMKKPIV
GFIAGVTAPPGKRMGHAGALISGGADTADAKLAIMEECGFTVTRNPSEMGKLLKGLL
>Mature_296_residues
SILINKNTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASVKEAAGQTGATVSVIYVPPAGA
AAAIWEAVEADLDLAICITEGIPVKDMLLVRNKMKAKEAAGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHKKGRIGVVS
RSGTLTYEAVAQLSELGLGQSSAVGIGGDPINGLKHIDVMRAFNDDPDTDAVIMIGEIGGPDEAEAARWCKANMKKPIVG
FIAGVTAPPGKRMGHAGALISGGADTADAKLAIMEECGFTVTRNPSEMGKLLKGLL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=292, Percent_Identity=54.1095890410959, Blast_Score=258, Evalue=4e-69,
Organism=Homo sapiens, GI38569423, Length=210, Percent_Identity=30.952380952381, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI38569421, Length=210, Percent_Identity=30.952380952381, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786949, Length=297, Percent_Identity=54.2087542087542, Blast_Score=307, Evalue=5e-85,
Organism=Caenorhabditis elegans, GI17550194, Length=293, Percent_Identity=53.5836177474403, Blast_Score=287, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI17553126, Length=301, Percent_Identity=51.4950166112957, Blast_Score=280, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17557344, Length=255, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=25.8823529411765, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324716, Length=300, Percent_Identity=46.6666666666667, Blast_Score=256, Evalue=4e-69,
Organism=Drosophila melanogaster, GI21356559, Length=296, Percent_Identity=49.6621621621622, Blast_Score=280, Evalue=6e-76,
Organism=Drosophila melanogaster, GI28574296, Length=296, Percent_Identity=52.7027027027027, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI281363477, Length=254, Percent_Identity=26.3779527559055, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363475, Length=254, Percent_Identity=26.3779527559055, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363473, Length=254, Percent_Identity=26.3779527559055, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30828; Mature: 30697

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKNTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASV
CEEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCHHHCCCCCCCCEEEEEH
KEAAGQTGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVKDMLLVRNKMKAKEA
HHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
AGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHKKGRIGVVSRSGTLTYEAVAQLSELGLG
CCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCC
QSSAVGIGGDPINGLKHIDVMRAFNDDPDTDAVIMIGEIGGPDEAEAARWCKANMKKPIV
CCCEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCE
GFIAGVTAPPGKRMGHAGALISGGADTADAKLAIMEECGFTVTRNPSEMGKLLKGLL
EHEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEHHCCCEEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SILINKNTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASV
EEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCHHHCCCCCCCCEEEEEH
KEAAGQTGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVKDMLLVRNKMKAKEA
HHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
AGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHKKGRIGVVSRSGTLTYEAVAQLSELGLG
CCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCC
QSSAVGIGGDPINGLKHIDVMRAFNDDPDTDAVIMIGEIGGPDEAEAARWCKANMKKPIV
CCCEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCE
GFIAGVTAPPGKRMGHAGALISGGADTADAKLAIMEECGFTVTRNPSEMGKLLKGLL
EHEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEHHCCCEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]