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The map label for this gene is sucC [H]

Identifier: 124265265

GI number: 124265265

Start: 66548

End: 67708

Strand: Reverse

Name: sucC [H]

Synonym: Mpe_A0072

Alternate gene names: 124265265

Gene position: 67708-66548 (Counterclockwise)

Preceding gene: 124265267

Following gene: 124265264

Centisome position: 1.67

GC content: 66.15

Gene sequence:

>1161_bases
ATGAAGATCCACGAATACCAAGGCAAAGAGATCCTGCGCCAGTTCGGCGTTCCGGTACCCCGCGGCTATCCGGCGTTCAC
CGGGCAGGAGGCCGTCGAGGCCGCCCAGAAGCTCGGCGGCCCGGTGTGGGTCGTGAAGGCGCAGATCCACGCAGGAGGCC
GCGGCAAGGGCGGCGGCGTGAAGCTCGGCAAGAGCCTGGACGAGGTGAAGGCACTGTCGGGCCAGATCCTGGGCATGCAG
CTCAAGACCCACCAGACCGGCCCCGAGGGCCAGAAGGTGCGGCGCCTGTACATCGAGGAAGGCGCGGACATCAAGAAGGA
ATATTACGTCTCGCTGGTGACCGACCGCGCGACGCAGAAGGTGGCCCTGATCGCCTCGAGCGAAGGCGGCATGGACATCG
AGGAGGTCGCGCACAGCACCCCCGAGAAGATCATCACCGAGGTGATCGATCCGCTGGCCGGCCTCGGCGACGCGCAGGCG
AAGAAGATCGCCGCCGCGATCGGCCTGCCGGAAGGCTCGCACGCCCAGGCGGTGACGCTGCTGCAGAACCTGTACCGCTG
CTACATGGAGACGGATGCCTCGCTGGTCGAGATCAATCCGCTGAACTGCGACAGCAAGGGCAACCTGATCGCGCTCGACG
CGAAGTTCAACTTCGACGCGAACGCCCTGTTCCGGCACCCCGAGATCGTCGCCTACCGCGACCTCGACGAGGAGGACCCG
GCCGAGATCGAGGCCAGCAAGTTCGACCTCGCCTACATCCAGCTCGACGGCAACATTGGCTGCCTGGTCAACGGCGCGGG
CCTGGCGATGGCGACGATGGACACCATCAAGCTGTTCGGCGGCGAGCCGGCCAACTTCCTCGACGTCGGTGGCGGCGCGA
CGGCCGAGAAGGTCACCGAGGCCTTCAAGATCATGCTGAAGAACCCCGAGGTCAAGGCCATCCTGGTCAACATCTTCGGC
GGCATCATGCGCTGCGACACGATCGCCGACGGCGTCGTCACCGCCTCGCGCGCGGTCGGTCTGAAGGTGCCGCTGGTGGT
GCGCATGAAGGGCACCAACGAAGACCTGGGCAAGAAGATCCTGGCCGACTCCGGCCTGCCGATCATCGCCGCCGACACCA
TGGCCGAAGCAGCCACCAAGGTTGTCGCCGCCGTCGCCTGA

Upstream 100 bases:

>100_bases
CTTTTCCCGGCGTGCCACCCGCGCCGTGCCGCCCGCGGGCGGGCGCCGAACCGTCCGACTTCTTCGACTCGAACCACCCA
CCCTCGAATCCAGCGCGACC

Downstream 100 bases:

>100_bases
GCCCTCGAAGGACACCGAACATGAGCATCCTGATCAACAAGAACACCAAGGTCATCACCCAGGGCATCACGGGCAAGACC
GGTCAGTTCCACACGCGCGG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKIHEYQGKEILRQFGVPVPRGYPAFTGQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGVKLGKSLDEVKALSGQILGMQ
LKTHQTGPEGQKVRRLYIEEGADIKKEYYVSLVTDRATQKVALIASSEGGMDIEEVAHSTPEKIITEVIDPLAGLGDAQA
KKIAAAIGLPEGSHAQAVTLLQNLYRCYMETDASLVEINPLNCDSKGNLIALDAKFNFDANALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYIQLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATAEKVTEAFKIMLKNPEVKAILVNIFG
GIMRCDTIADGVVTASRAVGLKVPLVVRMKGTNEDLGKKILADSGLPIIAADTMAEAATKVVAAVA

Sequences:

>Translated_386_residues
MKIHEYQGKEILRQFGVPVPRGYPAFTGQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGVKLGKSLDEVKALSGQILGMQ
LKTHQTGPEGQKVRRLYIEEGADIKKEYYVSLVTDRATQKVALIASSEGGMDIEEVAHSTPEKIITEVIDPLAGLGDAQA
KKIAAAIGLPEGSHAQAVTLLQNLYRCYMETDASLVEINPLNCDSKGNLIALDAKFNFDANALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYIQLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATAEKVTEAFKIMLKNPEVKAILVNIFG
GIMRCDTIADGVVTASRAVGLKVPLVVRMKGTNEDLGKKILADSGLPIIAADTMAEAATKVVAAVA
>Mature_386_residues
MKIHEYQGKEILRQFGVPVPRGYPAFTGQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGVKLGKSLDEVKALSGQILGMQ
LKTHQTGPEGQKVRRLYIEEGADIKKEYYVSLVTDRATQKVALIASSEGGMDIEEVAHSTPEKIITEVIDPLAGLGDAQA
KKIAAAIGLPEGSHAQAVTLLQNLYRCYMETDASLVEINPLNCDSKGNLIALDAKFNFDANALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYIQLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATAEKVTEAFKIMLKNPEVKAILVNIFG
GIMRCDTIADGVVTASRAVGLKVPLVVRMKGTNEDLGKKILADSGLPIIAADTMAEAATKVVAAVA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=48.586118251928, Blast_Score=357, Evalue=1e-98,
Organism=Homo sapiens, GI157779135, Length=378, Percent_Identity=47.8835978835979, Blast_Score=341, Evalue=8e-94,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=47.6323119777159, Blast_Score=324, Evalue=1e-88,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=52.5906735751295, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=45.9390862944162, Blast_Score=337, Evalue=7e-93,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=45.8974358974359, Blast_Score=333, Evalue=8e-92,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=47.1938775510204, Blast_Score=360, Evalue=1e-100,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=47.2727272727273, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=47.2727272727273, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=47.4093264248705, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=47.4093264248705, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI21356231, Length=393, Percent_Identity=45.0381679389313, Blast_Score=323, Evalue=2e-88,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 40940; Mature: 40940

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQGKEILRQFGVPVPRGYPAFTGQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KLGKSLDEVKALSGQILGMQLKTHQTGPEGQKVRRLYIEEGADIKKEYYVSLVTDRATQK
ECCCCHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHEEEEEECCCCCE
VALIASSEGGMDIEEVAHSTPEKIITEVIDPLAGLGDAQAKKIAAAIGLPEGSHAQAVTL
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHH
LQNLYRCYMETDASLVEINPLNCDSKGNLIALDAKFNFDANALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEECCCCHHEECCCCEEEECCCCCCCC
AEIEASKFDLAYIQLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATAEKVTE
CCEECCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFKIMLKNPEVKAILVNIFGGIMRCDTIADGVVTASRAVGLKVPLVVRMKGTNEDLGKKI
HHHHHHCCCCCEEEHEEHHHHHHHHHHHHCCHHHHHHHCCEECEEEEEECCCCHHHHHHH
LADSGLPIIAADTMAEAATKVVAAVA
HHCCCCCEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIHEYQGKEILRQFGVPVPRGYPAFTGQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KLGKSLDEVKALSGQILGMQLKTHQTGPEGQKVRRLYIEEGADIKKEYYVSLVTDRATQK
ECCCCHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHEEEEEECCCCCE
VALIASSEGGMDIEEVAHSTPEKIITEVIDPLAGLGDAQAKKIAAAIGLPEGSHAQAVTL
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHH
LQNLYRCYMETDASLVEINPLNCDSKGNLIALDAKFNFDANALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEEECCCCHHEECCCCEEEECCCCCCCC
AEIEASKFDLAYIQLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATAEKVTE
CCEECCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFKIMLKNPEVKAILVNIFGGIMRCDTIADGVVTASRAVGLKVPLVVRMKGTNEDLGKKI
HHHHHHCCCCCEEEHEEHHHHHHHHHHHHCCHHHHHHHCCEECEEEEEECCCCHHHHHHH
LADSGLPIIAADTMAEAATKVVAAVA
HHCCCCCEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA